Browsing Biomedical Engineering (Scholarly Articles) by Title
Now showing items 18-37 of 128
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Computational modelling of ovine critical-sized tibial defects with implanted scaffolds and prediction of the safety of fixator removal
(Elsevier, 2015-01-14)Computational model geometries of tibial defects with two types of implanted tissue engineering scaffolds, β-tricalcium phosphate (β-TCP) and poly-ε-caprolactone (PCL)/β-TCP, are constructed from µ-CT scan images of the ... -
Conceptualizing Industry 4.0 readiness model dimensions: an exploratory sequential mixed-method study
(Emerald, 2021-07-16)Purpose Organizations use Industry 4.0 readiness models to evaluate their preparedness prior to the implementation of Industry 4.0. Though there are many studies on Industry 4.0 readiness models, the dimensions of readiness ... -
Cooperative contractility: the role of stress fibres in the regulation of cell-cell junctions
(Elsevier, 2014-11-27)We present simulations of cell-cell adhesion as reported in a recent study [Liu et al., 2010, PNAS, 107(22), 9944-9] for two cells seeded on an array of micro-posts. The micro-post array allows for the measurement of forces ... -
A critical evaluation and measurement of organisational readiness and adoption for continuous improvement within a medical device manufacturer
(Taylor and Francis Group, 2022-05-24)This research aims to assess the organisational readiness and maturity of continuous improvement (CI) deployment in a medical device manufacturer. A single case study approach was used, in an Irish medical device company ... -
Critical failure factors for continuous improvement methodologies in the Irish MedTech industry
(Emerald, 2022-03-10)The main objective of this study is to investigate what are the critical success factors that exist for continuous improvement (CI) methodology deployment in the Irish medical technology (MedTech) industry. The research ... -
Design and manufacturing of customised maxillofacial prostheses.
(Elsevier, 2003-04-28)Customised implants created by Computer-Assisted Surgery (CAS) techniques and used in maxillofacial reconstruction indicate improved outcomes over conventional techniques. ‘‘Non-functional’’ multistaged procedures are ... -
Designing online delivery of lean education during COVID-19
(Emerald, 2023-08-23)This study describes how two organisations transitioned to teaching Lean online during and post Covid-19. The study aims to establish how Lean teaching and training can be designed and delivered effectively online without ... -
The development of a lean six sigma and BIM framework for enhancing off-site manufacturing
(Emerald, 2023-05-12)This project aims to improve a construction company's overall project delivery by utilising Lean Six sigma methods combined with Business Information Modeling (BIM) to design, modularise and manufacture various building ... -
Differential β3 and β1 integrin expression in bone marrow and cortical bone of estrogen deficient rats
(Wiley, 2015-08-12)Integrin-based (beta(3)) attachments to the extracellular matrix (ECM) on osteocyte cell processes have recently been proposed to play an important role in facilitating osteocyte mechanosensation. However, it is not yet ... -
DNA Immobilization and Detection on Cellulose Paper using a Surface Grown Cationic Polymer via ATRP
(American Chemical Society, 2012-02-02)Cationic polymers with various structures have been widely investigated in the areas of medical diagnostics and molecular, biology because of their unique binding properties and capability to interact with biological ... -
Does making method of alginate hydrogel influence the chondrogenic differentiation of human mesenchymal stem cells?
(Scientific Research Publishing, 2012-10)To overcome cartilage injury, strategies have been developed in the last few years based on tissue engineering to rebuild the defects. Cartilage engineering is principally based on three main biological factors: cells ... -
The effect of grain orientation on fretting fatigue plasticity and life prediction
(Elsevier ScienceDirect, 2014)A study on crystal and J2J2 plasticity prediction of fretting fatigue is presented, using a microstructure-sensitive fatigue parameter for crystal plasticity crack nucleation and a critical-plane (multiaxial) fatigue ... -
Effect of hydroxyapatite on biodegradable scaffolds fabricated by SLS
(Trans Tech Publications Ltd., 2009)Selective laser sintering (SLS) has the potential to fabricate bioresorbable polymer / ceramic composite scaffolds with pre-designed external and internal architecture that can be used for bone tissue engineering applications. ... -
The effect of intraluminal contact mediated guidance signals on axonal mismatch during peripheral nerve repair
(Elsevier, 2012-06-25)The current microsurgical gold standard for repairing long gap nerve injuries is the autograft. Autograft provides a protective environment for repair and a natural internal architecture, which is essential for regeneration. ... -
The effect of medical device regulations on deploying a Lean Six Sigma project
(MDPI, 2022-11-05)This paper investigates the differences in timelines involved in Lean Six Sigma (LSS) project deployment in a regulated industry versus in an unregulated one. Two case studies utilising Lean Six Sigma methods¿in order to ... -
The effect of remodelling and contractility of the actin cytoskeleton on the shear resistance of single cells: a computational and experimental investigation
(The Royal Society Publishing, 2012-07-18)The biomechanisms that govern the response of chondrocytes to mechanical stimuli are poorly understood. In this study, a series of in vitro tests are performed, in which single chondrocytes are subjected to shear deformation ... -
The effect of substrate stiffness, thickness, and cross-linking density on osteogenic cell behavior
(Biophysical Society, 2015-04-07)Osteogenic cells respond to mechanical changes in their environment by altering their spread area, morphology, and gene expression profile. In particular, the bulk modulus of the substrate, as well as its microstructure ... -
Effects of in vitro endochondral priming and pre-vascularisation of human MSC cellular aggregates in vivo
(2015)Introduction: During endochondral ossification, both the production of a cartilage template and the subsequent vascularisation of that template are essential precursors to bone tissue formation. Recent studies have found ... -
Effects of material thickness and processing method on poly(lactic-co-glycolic acid) degradation and mechanical performance
(Springer Verlag, 2016-09-02)In this study, the effects of material thickness and processing method on the degradation rate and the changes in the mechanical properties of poly(lactic-co-glycolic acid) material during simulated physiological degradation ... -
Electro-spinning of pure collagen nano-fibres – Just an expensive way to make gelatin?
(Elsevier, 2008-03-03)Scaffolds manufactured from biological materials promise better clinical functionality, providing that characteristic features are preserved. Collagen, a prominent biopolymer, is used extensively for tissue engineering ...