Browsing Biomedical Engineering (Scholarly Articles) by Title
Now showing items 29-48 of 128
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The effect of grain orientation on fretting fatigue plasticity and life prediction
(Elsevier ScienceDirect, 2014)A study on crystal and J2J2 plasticity prediction of fretting fatigue is presented, using a microstructure-sensitive fatigue parameter for crystal plasticity crack nucleation and a critical-plane (multiaxial) fatigue ... -
Effect of hydroxyapatite on biodegradable scaffolds fabricated by SLS
(Trans Tech Publications Ltd., 2009)Selective laser sintering (SLS) has the potential to fabricate bioresorbable polymer / ceramic composite scaffolds with pre-designed external and internal architecture that can be used for bone tissue engineering applications. ... -
The effect of intraluminal contact mediated guidance signals on axonal mismatch during peripheral nerve repair
(Elsevier, 2012-06-25)The current microsurgical gold standard for repairing long gap nerve injuries is the autograft. Autograft provides a protective environment for repair and a natural internal architecture, which is essential for regeneration. ... -
The effect of medical device regulations on deploying a Lean Six Sigma project
(MDPI, 2022-11-05)This paper investigates the differences in timelines involved in Lean Six Sigma (LSS) project deployment in a regulated industry versus in an unregulated one. Two case studies utilising Lean Six Sigma methods¿in order to ... -
The effect of remodelling and contractility of the actin cytoskeleton on the shear resistance of single cells: a computational and experimental investigation
(The Royal Society Publishing, 2012-07-18)The biomechanisms that govern the response of chondrocytes to mechanical stimuli are poorly understood. In this study, a series of in vitro tests are performed, in which single chondrocytes are subjected to shear deformation ... -
The effect of substrate stiffness, thickness, and cross-linking density on osteogenic cell behavior
(Biophysical Society, 2015-04-07)Osteogenic cells respond to mechanical changes in their environment by altering their spread area, morphology, and gene expression profile. In particular, the bulk modulus of the substrate, as well as its microstructure ... -
Effects of in vitro endochondral priming and pre-vascularisation of human MSC cellular aggregates in vivo
(2015)Introduction: During endochondral ossification, both the production of a cartilage template and the subsequent vascularisation of that template are essential precursors to bone tissue formation. Recent studies have found ... -
Effects of material thickness and processing method on poly(lactic-co-glycolic acid) degradation and mechanical performance
(Springer Verlag, 2016-09-02)In this study, the effects of material thickness and processing method on the degradation rate and the changes in the mechanical properties of poly(lactic-co-glycolic acid) material during simulated physiological degradation ... -
Electro-spinning of pure collagen nano-fibres – Just an expensive way to make gelatin?
(Elsevier, 2008-03-03)Scaffolds manufactured from biological materials promise better clinical functionality, providing that characteristic features are preserved. Collagen, a prominent biopolymer, is used extensively for tissue engineering ... -
Electromechanical properties of dried tendon and isoelectrically focused collagen hydrogels
(Elsevier, 2012-08)Assembling artificial collagenous tissues with structural, functional, and mechanical properties which mimic natural tissues is of vital importance for many tissue engineering applications. While the electro-mechanical ... -
An empirical study into the use of 7 quality control tools in higher education institutions (HEIs)
(Emerald, 2022-09-13)Ireland has developed a highly successful medical device cluster. Most of the industry started from USA multinationals that moved to Ireland in the 1990s. An ecosystem has now developed with strong linkages between ... -
An enhanced phenomenological model to predict surface-based localised corrosion of magnesium alloys for medical use
(Elsevier, 2023-01-05)This study developed an enhanced phenomenological model for the predictions of surface-based localised corrosion of magnesium alloys for use in medical applications. The modelling framework extended previous surface-based ... -
Estrogen deficiency impairs integrin αvβ3-mediated mechanosensation by osteocytes and alters osteoclastogenic paracrine signalling
(Nature Research (part of Springer Nature), 2019-03-15)The integrin alpha(v)beta(3) has been shown to play an important role in osteocyte mechanotransduction. It has been reported that there are fewer beta(3) integrin-containing cells in osteoporotic bone cells. Osteocytes ... -
Evaluating the effect of increasing ceramic content on the mechanical properties, material microstructure and degradation of selective laser sintered PCL/b-TCP materials
(Elsevier, 2015-06-06)Orthopaedic scaffold materials were fabricated from polycaprolactone (PCL) and composite PCL β-tricalcium phosphate (PCL/β-TCP) powders using selective laser sintering (SLS). Incorporating β-TCP particles is ... -
Evaluation of a multiscale modelling methodology to predict the mechanical properties of PCL/β-TCP sintered scaffold materials
(Springer Verlag, 2014-12-02)A multiscale modelling methodology to predict the macroscale stiffness of selective laser sintered polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) materials is evaluated. The relationship between a micromechanics-evaluated ... -
An evaluation of Lean and Six Sigma methodologies in the national health service
(Emerald, 2021-10-18)The purpose of this paper is to conduct an empirical study derived from previous literature from the perspective of benefits, tools and techniques, Continuous Improvement (CI) and Quality Improvement (QI) methodologies, ... -
The evolution and future of lean Six Sigma 4.0
(Emerald, 2022-05-24)Purpose This purpose of this study is to provide an overview of the current state of research on Lean Six Sigma (LSS) and Industry 4.0 and the key aspects of the relationships between them. The research analyses LSS's ... -
The evolution of Ireland’s medical device cluster and its future direction
(MDPI, 2022-08-16)Ireland has developed a highly successful medical device cluster. Most of the industry started from USA multinationals that moved to Ireland in the 1990s. An ecosystem has now developed with strong linkages between ... -
An experimental and computational investigation of the post-yield behaviour of trabecular bone during vertebral device subsidence
(Springer-Verlag, 2013)Interbody fusion device subsidence has been reported clinically. An enhanced understanding of the mechanical behaviour of the surrounding bone would allow for accurate predictions of vertebral subsidence. The multiaxial ... -
Experimental and computational investigation of the role of stress fiber contractility in the resistance of osteoblasts to compression
(2013)The mechanical behavior of the actin cytoskeleton has previously been investigated using both experimental and computational techniques. However, these investigations have not elucidated the role the cytoskeleton plays in ...