Browsing Biomedical Engineering (Scholarly Articles) by Title
Now showing items 106-125 of 128
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Recovery of cardiac function mediated by MSC and interleukin-10 plasmid functionalised scaffold
(2011-11)Stem cell transplantation has been suggested as a treatment for myocardial infarction, but clinical studies have yet to demonstrate conclusive, positive effects. This may be related to poor survival of the transplanted ... -
A review of Lean adoption in the Irish MedTech industry
(MDPI, 2022-02-17)There have been many literature reviews carried out on Lean implementation in larger organisations with specific focus on the automobile industry. Lean implementation in the medical device industry has not been extensively ... -
Revisiting Ishikawa's original seven basic tools of quality control: A global study and some new insights
(Institute of Electrical and Electronics Engineers (IEEE), 2021-07-26)The purpose of this global study is to investigate the validity of Dr. Ishikawa’s statement that “95% of problems in processes can be solved using the 7 Quality Control (QC) tools” in organizations. An online survey ... -
The role of integrin αVβ3 in osteocyte mechanotransduction
(Elsevier, 2014-11-10)Recent in vivo studies have proposed that integrin alpha(v)beta(3) attachments between osteocyte cell processes and the extracellular matrix may facilitate mechanosensation in bone. However the role of these attachments ... -
Selective laser sintering of hydroxyapatite/poly-epsilon-caprolactone scaffolds
(2010)Selective laser sintering (SLS) enables the fabrication of complex geometries with the intricate and controllable internal architecture required in the field of tissue engineering. In this study hydroxyapatite and ... -
Simulation of the Mechanical Response of Cells on Micropost Substrates
(American Society of Mechanical Engineers, 2013-09-20)Experimental studies where cells are seeded on micropost arrays in order to quantify their contractile behavior are becoming increasingly common. Interpretation of the data generated by this experimental technique is ... -
Single Cyclized Molecule Structure from RAFT Homopolymerization of Multi-vinyl Monomers
(2012)We explore a kinetically controlled strategy to suppress the gelation in the homopolymerization of multi-vinyl monomers (MVMs) via RAFT polymerization. We report the generation of 3D single cyclized polymer structures from ... -
Single Cyclized Molecule Versus Single Branched Molecule: A Simple and Efficient 3D "Knot" Polymer Structure for Nonviral Gene Delivery
(American Chemical Society, 2012-02-12)The large research effort focused on enhancing nonviral transfection vectors has clearly demonstrated that their macromolecular structure has a significant effect on their transfection efficacy. The 3D branched polymeric ... -
Six Sigma application in an Irish meat processing plant to improve process yields
(Emerald, 2023-05-22)This study aims to utilise Six Sigma in an Irish-based red meat processor to reduce process variability and improve yields. This is a case study within an Irish meat processor where the structured Define, Measure, Analyse, ... -
Stability enhancement of an atomic force microscope for long-term force measurement including cantilever modification for whole cell deformation
(2012)Atomic force microscopy (AFM) is widely used in the study of both morphology and mechanical properties of living cells under physiologically relevant conditions. However, quantitative experiments on timescales of minutes ... -
Strain amplification in bone mechanobiology: a computational investigation of the in vivo mechanics of osteocytes
(The Royal Society Publishing, 2012-06-06)The osteocyte is believed to act as the main sensor of mechanical stimulus in bone, controlling signalling for bone growth and resorption in response to changes in the mechanical demands placed on our bones throughout life. ... -
A study into the pros and cons of ISO 18404: Viewpoints from leading academics and practitioners
(Emerald, 2021-03-23)Abstract Purpose This paper aims to present and summarise the arguments for and against the ISO 18404 standard and the perceived advantages and disadvantages of implementing it. Design/methodology/approach ... -
A study on Ishikawa’s original basic tools of quality control in healthcare
(Emerald, 2022-08-30)The main objective of this study is to investigate Ishikawa¿s statement that ¿95% of problems in processes can be accomplished using the 7 Quality Control (QC) tools¿ and explore its validity within the healthcare sector. ... -
A study on the Ishikawa's original basic tools of quality control in South American companies: results from a pilot survey and directions for further research
(Emerald, 2021-03-09)The main purpose of this study is to revisit Dr. Ishikawa s statement: 95% of problems in processes can be accomplished using the 7 Quality Control (QC) tools from his book What is Quality Control? . The authors are ... -
The sustainable impact of the use of science based targets in organisations
(Sciendo, 2023-12-06)Due to the increase in gas emissions and the growth of environmental problems globally, companies are striving to reduce their emissions and waste products in order to become more sustainable and preserve the environment. ... -
The tensile ductility of cellular solids: the role of imperfections
(Elsevier, 2016-10-11)Metallic and polymeric foams typically possess a low tensile failure strain of a few percent despite the fact that the parent solid can have high ductility (10% or more). This is remarkable as foams are bending-dominated ... -
Thermally induced osteocyte damage initiates a remodelling signaling cascade
(Public Library of Science, 2015-03-18)Thermal elevations experienced by bone during orthopaedic procedures, such as cutting and drilling, exothermal reactions from bone cement, and thermal therapies such as tumor ablation, can result in thermal damage leading ... -
A thermodynamically motivated model for stress-fiber reorganization
(Springer Verlag, 2015-09-04)We present a model for stress-fiber reorganization and the associated contractility that includes both the kinetics of stress-fiber formation and dissociation as well as the kinetics of stress-fiber remodeling. These ... -
A three-scale finite element investigation into the effects of tissue mineralisation and lamellar organisation in human cortical and trabecular bone
(Elsevier, 2012-03-20)Bone is an exceptional material that is lightweight for efficient movement but also exhibits excellent strength and stiffness imparted by a composite material of organic proteins and mineral crystals that are intricately ... -
A through-process, thermomechanical model for predicting welding-induced microstructure evolution and post-weld high-temperature fatigue response
(Elsevier, 2018-02-11)This paper is concerned with the development of a modelling framework to predict the effects of welding and post-weld heat treatment on thereto-mechanical performance of welded material, as a step towards a design tool for ...