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Now showing items 1531-1540 of 1724
Inventing Liberia: imagining and representing colony and nation in American, Liberian and European writing 1820-1940
(NUI Galway, 2018-10-11)
Liberia, the West African nation, whose name connotes freedom, was the creation of the American Colonisation Society (ACS) whose initial aim was to rid the United States of a growing population of ‘free people of colour.’ ...
Environmental and genetic risk factors in Autism Spectrum Disorder: a stereological study
(NUI Galway, 2020-07-15)
Autism spectrum disorders (ASD), include a group of heterogeneous
neurodevelopmental disorders (NDDs) characterized by impaired social interaction,
and communication with restricted patterns of behaviour. The aetiology ...
Mechanistic insights into novel cellular therapy strategies for the treatment of corneal allograft rejection
(NUI Galway, 2019-02-14)
It has previously been demonstrated by our lab that tolerogenic dendritic cells (tDCs) prolong corneal allograft survival. This study revealed that tDCs had significantly higher levels of sialic acid on the cell surface ...
In vitro, pre-clinical and commercial evaluation of a novel xeno- and serum-free culture system for production of human bone marrow derived mesenchymal stem cells for bone regeneration
(2016-10-21)
The therapeutic potential of mesenchymal stem cells (MSCs) is recognised in treating a wide range of debilitating diseases. For clinical-scale manufacturing, serum-free and xenogenic-free media formulations have been ...
Medieval settlement enclosures and resource management of living trees in Gaelic Ireland
(NUI Galway, 2019-08-23)
The aim of this thesis is to problematise and investigate relationships between living trees and earthen settlement enclosures, mainly termed ráth and commonly used by Gaelic society in medieval Ireland (c. 8th – 17th ...
The role of the liver X receptor in mitotane therapy in adrenocortical carcinoma
(NUI Galway, 2020-08-12)
Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with limited treatment options. The Liver X Receptor α (LXRα) is highly expressed in the adrenal cortex, and functions to regulate cholesterol and lipid ...
A life course perspective: Life course learning for adult learners in Higher Education - an examination of the NUI Diploma in Applied Social Studies and the BA in Applied Social Studies
(NUI Galway, 2018-09-28)
This research study examines the concept of the life course and why it may be considered an issue of critical importance in the context of teaching and learning policy and practice for adult learners in higher education. ...
Using Total Internal Reflection Fluorescence Microscopy (TIRFM) for studying protein-surface interactions
(NUI Galway, 2018-09-10)
Total internal reflection fluorescence microscopy (TIRFM) techniques play an important role in investigating phenomena which occur on transparent dielectric surfaces at nanometre scales in various research fields from ...
Potential and optimisation of agriculture-based anaerobic digestion for environmental mitigation of agriculture-associated pollution
(NUI Galway, 2020-12-10)
The current work has taken a holistic approach to understanding the potential for mitigation of pollution from agriculture using anaerobic digestion (AD), with a particular focus on reduction of pathogen load to the ...
Spatial analysis of rare earth elements and lead in urban soils of Greater London Authority area and development of a new method for assessment of labile rare earth elements in soils
(NUI Galway, 2019-08-30)
Rare earth elements (REEs) are a group of seventeen elements, comprised of the fifteen lanthanides, yttrium (Y) and scandium (Sc), which have been known as ‘industrial vitamins’ due to their important roles in technical ...