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Rehabilitation approaches in dementia: an evaluation of three interventions from an occupational therapy perspective
(2017-01-25)
Dementia is a complex, progressively degenerative condition resulting in loss of cognitive and functional capabilities, along with a significant increase in degree of dependency.
In recent years a number of non-pharmacological ...
The legacy of the Irish Parliamentary Party in Independent Ireland, 1922-49
(2016)
This study provides the first detailed analysis of the influence and persistence of Irish Party individuals, organisations and political culture in independent Ireland (1922-49). While many former followers remained ...
Genetic analysis of ATR, a central regulator of genome stability.
(2016-05-11)
To protect the DNA against the constant assaults of endogenous and environmental agents, cells have developed conserved signaling pathways, known as the DNA damage response. Such responses are important to maintain genome ...
Unemployment inflows and outflows in the UK: a micro economometric analysis
(2016-06-09)
The unemployment rate is a function of both the inflows to unemployment and the outflows from unemployment. Understanding the unemployment rate requires an understanding of the flows that drive the rate. This thesis ...
Multimodal gold nanoprobes for optical imaging and therapy of cancer
(2016-05-20)
In the recent past, there has been an accelerated development in medical modalities for the early diagnosis and treatment of cancer. Tissue conservation of neighbouring healthy tissue and development of a minimally/non-invasive ...
A clinical evaluation of remote ischaemic preconditioning for organ protection
(2016-05-24)
Periprocedural complications are an issue for patients with cardiovascular disease. Remote ischaemic preconditioning (RIPC) may offer periprocedural organ protection. Although the proof of concept data underpinning RIPC ...
Pro-survival pathways in triple negative breast cancer: Focus on the roles of RIP2 and HSPB1
(2016-10-10)
Triple negative breast cancers (TNBC) lack estrogen and progesterone receptors, and HER-2 markers rendering them resistant to current targeted therapies. Most TNBCs show basal-like characteristics and the terms TNBC and ...
Smart biomaterials for cell sheet engineering
(2016-03-23)
The aim of this instigation was to develop thermoresponsive polymer films for cell culture use. Conventional cell detachment methods involve the use of proteolytic enzymes, such as trypsin, or mechanical scrapping. These ...
Experimental characterisation and computational constitutive modelling of high temperature degradation in 9Cr steels including microstructural effects
(2016-04-20)
The transition from base-load to intermittent power plant operation has led to the requirement for increased knowledge and more accurate prediction of the effects of flexible loading on plant components. This thesis is ...
Wave-structure interaction of offshore wave energy converters
(2013-11-04)
With the continuing rise in oil prices and greater concern for the damage to the atmosphere, the world is continually looking for a cleaner and more sustainable form of energy. Ocean wave energy as a renewable source of ...