This study provides the first detailed analysis of the influence and persistence of Irish Party individuals, organisations and political culture in independent Ireland (1922-49). While many former followers remained ...

To protect the DNA against the constant assaults of endogenous and environmental agents, cells have developed conserved signaling pathways, known as the DNA damage response. Such responses are important to maintain genome ...

The unemployment rate is a function of both the inflows to unemployment and the outflows from unemployment. Understanding the unemployment rate requires an understanding of the flows that drive the rate. This thesis ...

In the recent past, there has been an accelerated development in medical modalities for the early diagnosis and treatment of cancer. Tissue conservation of neighbouring healthy tissue and development of a minimally/non-invasive ...

Periprocedural complications are an issue for patients with cardiovascular disease. Remote ischaemic preconditioning (RIPC) may offer periprocedural organ protection. Although the proof of concept data underpinning RIPC ...

Triple negative breast cancers (TNBC) lack estrogen and progesterone receptors, and HER-2 markers rendering them resistant to current targeted therapies. Most TNBCs show basal-like characteristics and the terms TNBC and ...

The aim of this instigation was to develop thermoresponsive polymer films for cell culture use. Conventional cell detachment methods involve the use of proteolytic enzymes, such as trypsin, or mechanical scrapping. These ...

The transition from base-load to intermittent power plant operation has led to the requirement for increased knowledge and more accurate prediction of the effects of flexible loading on plant components. This thesis is ...

This thesis focuses on early modern Barbary captivity narratives which describe Christian encounters with the Islamic world, and gives particular attention to questions of sexuality and gender. From the short fledgling ...

This thesis begins with the premise that freedom of expression is the cornerstone of a democracy and any limitation on it must be prescribed by law, be in support of a legitimate aim and be necessary in a democratic society. ...