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Poynting effect of brain matter in torsion
(Royal Society of Chemistry, 2019-06-13)We investigate experimentally and model theoretically the mechanical behaviour of brain matter in torsion. Using a strain-controlled rheometer, we perform torsion tests on fresh porcine brain samples. We quantify the torque ... -
Metal-based glycoconjugates and their potential in targeted anticancer chemotherapy
(De Gruyter Open, 2016-04-07)Glucose is a key source of energy and an essential nutrient for cell growth. Rapidly dividing cancer cells are well-known to require more nutrients and energy than normal ones to sustain their higher proliferation ... -
Pathogenic bacteria in our oceans' shellfish
(Microbiology Society, 2019-02)Mussels, oysters, clams – some of the most appetising culinary dishes, such as moules-frites, feature shellfish. These foods are considered healthy as they are fresh from the ocean, but looks can be deceiving. -
1064 nm acoustic resolution photoacoustic microscopy
(Wiley, 2018-12-03)Photoacoustic imaging is a noninvasive imaging technique having the advantages of high-optical contrast and good acoustic resolution at improved imaging depths. Light transport in biological tissues is mainly characterized ... -
Influence of initial residual stress on growth and pattern creation for a layered aorta
(Nature Research, 2019-06-03)Residual stress is ubiquitous and indispensable in most biological and artificial materials, where it sustains and optimizes many biological and functional mechanisms. The theory of volume growth, starting from a stress-free ... -
Effect of individual plasma components on the performance of a glucose enzyme electrode based on redox polymer mediation of a flavin adenine dinucleotide-dependent glucose dehydrogenase
(Elsevier, 2019-02-11)The performance of glucose enzyme electrodes, consisting of crosslinked flavin adenine dinucleotide glucose dehydrogenase (FADGDH), an osmium redox polymer and multi-walled carbon nanotubes on graphite electrodes, was ... -
Glucose biosensor based on open-source wireless microfluidic potentiostat
(Elsevier, 2019-02-17)Wireless potentiostats capable of cyclic voltammetry and amperometry that connect to the Internet are emerging as key attributes of future point-of-care devices. This work presents an "integrated microfluidic electrochemical ... -
The influence of surface composition of carbon nanotubes on the photobioelectrochemical activity of thylakoid bioanodes mediated by osmium-complex modified redox polymer
(Elsevier, 2019-04-17)A combination of photosynthetic biocatalysts with high surface area conductive materials mediated by an osmium-complex modified redox polymer (OsRP) holds promising features for the development of sustainable "green" systems ... -
A thermodynamic model of auto-regulated protein assembly by a supramolecular scaffold
(Wiley, 2019-03-12)Ligand-mediated regulation of protein assembly occurs frequently in different cellular contexts. Auto-regulated assembly, where a ligand acts as its own competitive inhibitor, provides a mechanism for exquisite control of ... -
Rivlin's legacy in continuum mechanics and applied mathematics
(The Royal Society, 2019-03-18)Over a long and distinguished career, Ronald Rivlin (figure 1) published more than 200 scientific papers. He was a highly innovative scientist who made seminal contributions in all areas of continuum mechanics. He was one ... -
Tuning the pull-in instability of soft dielectric elastomers through loading protocols
(Elsevier, 2019-03-22)Pull-in (or electro-mechanical) instability occurs when a drastic decrease in the thickness of a dielectric elastomer results in electrical breakdown, which limits the applications of dielectric devices. Here we derive the ... -
Investigation of the formation of drug-drug cocrystals and coamorphous systems of the antidiabetic drug gliclazide
(Elsevier, 2019-02-23)The antidiabetic drug gliclazide (GLZ) has a slow absorption rate and a low bioavailability due to its poor solubility. GLZ is often prescribed along with an antihypertensive, as many diabetic patients have coexistent ... -
Conversion of gel-forming crystal needles to easily processable more equant crystals Using high-shear ultralow attrition agitation: accelerated Ostwald ripening without crystal attrition
(American Chemical Society, 2019-02-01)We demonstrate the first examples of the transformation of gel-forming crystal needles into easily processable more equant crystals by accelerated Ostwald ripening without detectable crystal attrition. Using high solution ... -
Cytotoxicity and ROS production of novel Pt(IV) oxaliplatin derivatives with indole propionic acid
(Elsevier, 2019-04-19)The coordination of biologically active moieties to the axial positions of Pt(IV) derivatives of Pt(II) anticancer drugs allows the co-delivery and simultaneous activation of two pro-drugs for combination therapy. Pt(IV) ... -
Wrinkles in soft dielectric plates
(Elsevier, 2018-07-04)We show that a smooth giant voltage actuation of soft dielectric plates is not easily obtained in practice. In principle one can exploit, through pre-deformation, the snap-through behavior of their loading curve to deliver ... -
Fine tuning the electro-mechanical response of dielectric elastomers
(AIP Publishing, 2018-10-16)We propose a protocol to model accurately the electromechanical behavior of dielectric elastomer membranes using experimental data of stress-stretch and voltage-stretch tests. We show how the relationship between electric ... -
Effects of nerve bundle geometry on neurotrauma evaluation
(Wiley, 2018-06-16)ObjectiveWe confirm that alteration of a neuron structure can induce abnormalities in signal propagation for nervous systems, as observed in brain damage. Here, we investigate the effects of geometrical changes and damage ... -
Finite bending and pattern evolution of the associated instability for a dielectric elastomer slab
(Elsevier, 2018-09-21)We investigate the finite bending and the associated bending instability of an incompressible dielectric slab subject to a combination of applied voltage and axial compression, using nonlinear electro-elasticity theory and ... -
Synthesis of benzoylated beta-D-glucosamine derivatives
(CRC Press / Taylor and Francis Group, 2017-09-19)[No abstract available] -
Ligand design for somatostatin receptor isoforms 4 and 5
(Elsevier, 2018-11-17)The somatostatin receptor (SSTR) isoforms, SSTR-4 and SSTR-5 are targets in numerous disorders and diseases. Although there has been some success in achieving selective isoform inhibition, structure-based drug design and ...