School of Physics
Browse by
Collections in this community
Recent Submissions
-
Characterization of an amplified piezoelectric actuator for multiple reference optical coherence tomography
(Optica, 2018-08-30)The characterization of an amplified piezoelectric actuator (APA) as a new axial scanning method for multiple-reference optical coherence tomography (MR-OCT) is described. MR-OCT is a compact optical imaging device based ... -
Feasibility of correlation mapping optical coherence tomography angiographic technique using a 200 kHz vertical-cavity surface-emitting laser source for in vivo microcirculation imaging applications
(Optica, 2018-08-01)Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow ... -
Interference method for determination of the refractive index and thickness
(Society of Photo-optical Instrumentation Engineers, 2000-09-01)The interference method for simultaneous measurement of the absolute refractive index and the thickness of plane parallel samples is developed. This method enables us to test solid (including optical glasses, crystals, ... -
Functional imaging for regenerative medicine
(BMC, 2016-04-19)In vivo imaging is a platform technology with the power to put function in its natural structural context. With the drive to translate stem cell therapies into pre-clinical and clinical trials, early selection of the right ... -
Synthetic aperture Fourier holographic optical microscopy
(American Physical Society, 2006-10-18)We report a new synthetic aperture optical microscopy in which high-resolution, wide-field amplitude and phase images are synthesized from a set of Fourier holograms. Each hologram records a region of the complex two-dimensional ... -
Microscopic particle discrimination using spatially-resolved Fourier-holographic light scattering angular spectroscopy
(Optica, 2006-11-13)We utilize Fourier-holographic light scattering angular spectroscopy to record the spatially resolved complex angular scattering spectra of samples over wide fields of view in a single or few image captures. Without resolving ... -
Audio frequency in vivo optical coherence elastography
(IOP Publishing, 2009-05-06)We present a new approach to optical coherence elastography (OCE), which probes the local elastic properties of tissue by using optical coherence tomography to measure the effect of an applied stimulus in the audio frequency ... -
High-resolution, wide-field object reconstruction with synthetic aperture Fourier holographic optical microscopy
(Optica, 2009)We utilize synthetic-aperture Fourier holographic microscopy to resolve micrometer-scale microstructure over millimeter-scale fields of view. Multiple holograms are recorded, each registering a different, limited region ... -
Three-dimensional depth-resolved and extended-resolution micro-particle characterization by holographic light scattering spectroscopy
(Optica, 2010)Fourier-holographic light scattering spectroscopy is applied to record complex angular scattering spectra of two- and three-dimensional samples over a wide field of view. We introduce a computational depth sectioning ... -
Real-time quantitative visualization of 3D structural information
(Optica, 2012)We demonstrate a novel approach for the real time visualization and quantification of the 3D spatial frequencies in an image domain. Our approach is based on the spectral encoding of spatial frequency principle and permits ... -
Label-free ultra-sensitive visualization of structure below the diffraction resolution limit
(Wiley, 2018-03-23)For both fundamental study of biological processes and early diagnosis of diseases, information about nanoscale changes in tissue and cell structure is crucial. Nowadays, almost all currently known nanoscopy methods rely ... -
Spectral encoding of spatial frequency approach for characterization of nanoscale structures
(American Institute of Physics, 2012-07-17)An approach to acquire axial structural information at nanoscale is demonstrated. It is based on spectral encoding of spatial frequency principle to reconstruct the structural information about the axial profile of the ... -
Simultaneous en-face imaging of multiple layers with multiple reference optical coherence tomography
(Society of Photo-optical Instrumentation Engineers, 2017-08-22)A technique based on multiple reference optical coherence tomography (MR-OCT) is proposed for simultaneous imaging at multiple depths. The technique has been validated by imaging a reference sample and a fingerprint in-vivo. ... -
Simple characterization scheme for optical coherence tomography systems with application to a commercial and a near-isometric resolution fibre-based system
(2021-12-14)Optical Coherence Tomography (OCT) is a rapidly growing imaging modality in biomedical optics. OCT can perform high-resolution, cross-sectional imaging of the microstructure of biological tissues by measuring the coherent ... -
Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in human milk from Ireland: temporal trends and implications for nursing infant exposure
(OAE Publishing Inc, 2021-11-19)Aim: The elucidation of temporal trends in human exposure to polychlorinated biphenyls (PCBs) and 17 polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) since the previous Irish human milk surveys and to evaluate the ... -
Nanosensitive optical coherence tomography to assess wound healing within the cornea
(Optical Society of America, 2020-05-01)Optical coherence tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though ... -
Noninvasive detection of nanoscale structural changes in cornea associated with cross-linking treatment
(Wiley, 2020-02-17)Corneal cross-linking (CXL) using ultraviolet-A (UVA) irradiation with a riboflavin photosensitizer has grown from an interesting concept to a practical clinical treatment for corneal ectatic diseases globally, such as ... -
Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression
(Society of Photo-optical Instrumentation Engineers, 2021-01-11)Significance: Assessment of disease using optical coherence tomography is an actively investigated problem, owing to many unresolved challenges in early disease detection, diagnosis, and treatment response monitoring. The ... -
Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal
(Nature Research, 2021-08-24)Optical coherence tomography (OCT) is a rapidly evolving technology with a broad range of applications, including biomedical imaging and diagnosis. Conventional intensity-based OCT provides depth-resolved imaging with a ... -
Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography
(Royal Society of Chemistry, 2020-05-25)Approximately 90% of cancers originate in epithelial tissues leading to epithelial thickening, but the ultrastructural changes and underlying architecture are less well known. Depth resolved label free visualization of ...