• Framework for developing an exposure science curriculum as part of the European Exposure Science Strategy 2020–2030 

  Connolly, Alison; Scheepers, Paul T. J.; Coggins, Marie; Vermeire, Theo; van Tongeren, Martie; Heinemeyer, Gerhard; Bridges, James W.; Bredendiek-Kämper, Susanne; Bruinen de Bruin, Yuri; Clayson, Anne; Gerding, Johannes; McCourt, Josephine; Urbanus, Jan; Viegas, Susana; von Goetz, Natalie; Zare-Jeddi, Maryam; Fantke, Peter (Elsevier, 2022-08-20)

  Background Evaluating and managing exposures to chemical, physical and biological stressors, which frequently interplay with psychological stressors as well as social and behavioural aspects, is crucial for protecting ...

• Halogenated flame retardants in Irish waste polymers: Concentrations, Legislative compliance, and preliminary assessment of temporal trends 

  Drage, Daniel; Sharkey, Martin; Al-Omran, Layla Salih; Stubbings, William A.; Berresheim, Harald; Coggins, Marie; Rosa, André Henrique; Harrad, Stuart (Elsevier, 2022-07-20)

  Halogenated flame retardants (HFRs) were measured in 470 waste plastic articles from Ireland between 2019 and 2020. We identified articles containing concentrations of polybrominated diphenyl ethers (PBDEs), hexabromocyclododecane ...

• The invisible barrier to safe textile recycling 

  Sharkey, Martin; Coggins, Marie (Frontiers Media, 2022-06-14)

  Presence of certain chemical additives (e.g. halogenated flame retardants, perfluoroalkyl substances, and phthalates) could hinder textile recycling operations as their presence renders end-of-life materials as “hazardous” ...

• Indoor air quality, thermal comfort and ventilation in deep energy retrofitted Irish dwellings 

  Coggins, Ann Marie; Wemken, Nina; Kumar Mishra, Asit; Sharkey, Martin; Horgan, Liam; Cowie, Hilary; Bourdin, Emmanuel; McIntyre, Brian (Elsevier, 2022-05-28)

  Residential building stock energy retrofits will play a key role in EU climate actions. The impact of these retrofits on indoor air quality (IAQ) and occupant comfort needs to be assessed to inform future renovation ...

• Characterization of an amplified piezoelectric actuator for multiple reference optical coherence tomography 

  O'Gorman, Sean; Neuhaus, Kai; Alexandrov, Sergey; Hogan, Josh; Wilson, Carol; McNamara, Paul M.; Leahy, Martin (Optica, 2018-08-30)

  The characterization of an amplified piezoelectric actuator (APA) as a new axial scanning method for multiple-reference optical coherence tomography (MR-OCT) is described. MR-OCT is a compact optical imaging device based ...

• Feasibility of correlation mapping optical coherence tomography angiographic technique using a 200 kHz vertical-cavity surface-emitting laser source for in vivo microcirculation imaging applications 

  Lal, Cerine; Subhash, Hrebesh M.; Alexandrov, Sergey; Leahy, Martin J. (Optica, 2018-08-01)

  Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow ...

• Interference method for determination of the refractive index and thickness 

  Alexandrov, Sergey; Chernyh, Igor V. (Society of Photo-optical Instrumentation Engineers, 2000-09-01)

  The interference method for simultaneous measurement of the absolute refractive index and the thickness of plane parallel samples is developed. This method enables us to test solid (including optical glasses, crystals, ...

• Functional imaging for regenerative medicine 

  Leahy, Martin; Thompson, Kerry; Zafar, Haroon; Alexandrov, Sergey; Foley, Mark; O’Flatharta, Cathal; Dockery, Peter (BMC, 2016-04-19)

  In vivo imaging is a platform technology with the power to put function in its natural structural context. With the drive to translate stem cell therapies into pre-clinical and clinical trials, early selection of the right ...

• Synthetic aperture Fourier holographic optical microscopy 

  Alexandrov, Sergey; Hillman, Timothy R.; Gutzler, Thomas; Sampson, David D. (American Physical Society, 2006-10-18)

  We report a new synthetic aperture optical microscopy in which high-resolution, wide-field amplitude and phase images are synthesized from a set of Fourier holograms. Each hologram records a region of the complex two-dimensional ...

• Microscopic particle discrimination using spatially-resolved Fourier-holographic light scattering angular spectroscopy 

  Hillman, Timothy R.; Alexandrov, Sergey; Gutzler, Thomas; Sampson, David D. (Optica, 2006-11-13)

  We utilize Fourier-holographic light scattering angular spectroscopy to record the spatially resolved complex angular scattering spectra of samples over wide fields of view in a single or few image captures. Without resolving ...

• Audio frequency in vivo optical coherence elastography 

  Adie, Steven G.; Kennedy, Brendan F.; Armstrong, Julian J.; Alexandrov, Sergey; Sampson, David (IOP Publishing, 2009-05-06)

  We present a new approach to optical coherence elastography (OCE), which probes the local elastic properties of tissue by using optical coherence tomography to measure the effect of an applied stimulus in the audio frequency ...

• High-resolution, wide-field object reconstruction with synthetic aperture Fourier holographic optical microscopy 

  Hillman, Timothy R.; Gutzler, Thomas; Alexandrov, Sergey; Sampson, David (Optica, 2009)

  We utilize synthetic-aperture Fourier holographic microscopy to resolve micrometer-scale microstructure over millimeter-scale fields of view. Multiple holograms are recorded, each registering a different, limited region ...

• Three-dimensional depth-resolved and extended-resolution micro-particle characterization by holographic light scattering spectroscopy 

  Gutzler, Thomas; Hillman, Timothy R.; Alexandrov, Sergey; Sampson, David D. (Optica, 2010)

  Fourier-holographic light scattering spectroscopy is applied to record complex angular scattering spectra of two- and three-dimensional samples over a wide field of view. We introduce a computational depth sectioning ...

• Real-time quantitative visualization of 3D structural information 

  Alexandrov, Sergey; Uttam, Shikhar; Bista, Rajan K.; Zhao, Chengquan; Liu, Yang (Optica, 2012)

  We demonstrate a novel approach for the real time visualization and quantification of the 3D spatial frequencies in an image domain. Our approach is based on the spectral encoding of spatial frequency principle and permits ...

• Label-free ultra-sensitive visualization of structure below the diffraction resolution limit 

  Alexandrov, Sergey; McGrath, James; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Hogan, Josh; Leahy, Martin (Wiley, 2018-03-23)

  For both fundamental study of biological processes and early diagnosis of diseases, information about nanoscale changes in tissue and cell structure is crucial. Nowadays, almost all currently known nanoscopy methods rely ...

• Spectral encoding of spatial frequency approach for characterization of nanoscale structures 

  Alexandrov, Sergey; Uttam, Shikhar; Bista, Rajan K.; Staton, Kevin; Liu, Yang (American Institute of Physics, 2012-07-17)

  An approach to acquire axial structural information at nanoscale is demonstrated. It is based on spectral encoding of spatial frequency principle to reconstruct the structural information about the axial profile of the ...

• Simultaneous en-face imaging of multiple layers with multiple reference optical coherence tomography 

  Neuhaus, Kai; O’Gorman, Seán; McNamara, Paul M.; Alexandrov, Sergey; Hogan, Josh; Wilson, Carol; Leahy, Martin J. (Society of Photo-optical Instrumentation Engineers, 2017-08-22)

  A technique based on multiple reference optical coherence tomography (MR-OCT) is proposed for simultaneous imaging at multiple depths. The technique has been validated by imaging a reference sample and a fingerprint in-vivo. ...

• Simple characterization scheme for optical coherence tomography systems with application to a commercial and a near-isometric resolution fibre-based system 

  Dey, Rajib; Zhou, Yi; Neuhaus, Kai; Alexandrov, Sergey; Nolan, Andrew; Chang, Ting-Chiao; Leahy, Martin (2021-12-14)

  Optical Coherence Tomography (OCT) is a rapidly growing imaging modality in biomedical optics. OCT can perform high-resolution, cross-sectional imaging of the microstructure of biological tissues by measuring the coherent ...

• Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in human milk from Ireland: temporal trends and implications for nursing infant exposure 

  Houlihan, Margarete; Wemken, Nina; Keogh, Myra; O’Riordain, Colman; Noone, Conor; Tierney, Julie; Claire Cellarius, Claire; Cleere, Kathy; Morrison, John J.; Daly, Sean; Harrad, Stuart; Tlustos, Christina; Coggins, Marie Ann (OAE Publishing Inc, 2021-11-19)

  Aim: The elucidation of temporal trends in human exposure to polychlorinated biphenyls (PCBs) and 17 polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) since the previous Irish human milk surveys and to evaluate the ...

• Nanosensitive optical coherence tomography to assess wound healing within the cornea 

  Lal, Cerine; Alexandrov, Sergey; Rani, Sweta; Zhou, Yi; Ritter, Thomas; Leahy, Martin (Optical Society of America, 2020-05-01)

  Optical coherence tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though ...

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