Recent Submissions

  • SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation 

    Onwubiko, Nichodemus O.; Scheffel, Felicia; Tessmer, Ingrid; Nasheuer, Heinz-Peter (Wiley Open Access and Federation of European Biochemical Societies, 2022-01-24)
    The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase ¿-primase (Pol-prim). Since cellular ...
  • Lectin microarray profiling demonstrates equivalent global glycosylation for whey protein ingredients enriched with α-lactalbumin and milk fat globule membrane 

    Le Berre, Marie; Joubran, Yousef; Joshi, Lokesh; O'Regan, Jonathan; Kilcoyne, Michelle (Elsevier, 2022-12-22)
    Human milk fat globule membrane (MFGM) and whey proteins are nutritionally and functionally valuable, with many beneficial bioactivities associated with their glycosylation. However glycosylation of milk components other ...
  • Discovery and recovery of an exceptional accumulation of carboniferous echinoids at Hook Head, Wexford 

    Álvarez-Armada, Nidia; Murray, John; Gatley, Sarah; Ciborowski, T. Jake R.; Parkes, Matthew A. (Royal Irish Academy, 2022-09-30)
    Geoconservation is a burgeoning area of activity within the Earth sciences and the preservation of significant fossil finds remains crucial for the advancement of palaeontological knowledge and protection of geoheritage. ...
  • North Eastern Atlantic cephalopods stock assessment in a data limited framework Surplus Production in a Continuous Time (SPiCT): Annex1to WP.4.2deliverable 

    Larivain, Angela; Petroni, Michael; Iriondo, Ane; Abad, Esther; Valeiras, Julio; Moreno, Ana; Dinis, David; Rocha, Alberto; Laptikovsky, Vladimir; Robin, Jean-Paul; Power, Anne Marie (Cephs and Chefs (Interreg Atlantic Area Community Engagement Publications), 2021)
    The lack of management leaves fishery resources vulnerable to increases in fishing pressure.Although some cephalopods are of commercial importance, most of Northeast Atlantic stocks are non-quota ...
  • Cephalopod recipes 2021: 21 recipes for octopus, cuttlefish and squid from Spain, France, Ireland and Portugal 

    Roumbedakis, C.; Amiero, J.; Pita, C.; Longo, C.; Montero, C.; Mendes, R.; Matos, F.; Monteiro, S.; Larivain, A.; Davoren, Sadie; O'Leary, A.; Lago, R.; Romón, J.; Pierce, G. J.; Power, Anne Marie (Cephs and Chefs (Interreg Atlantic Area Community Engagement Publications), 2021)
    [No abstract available]
  • Examination of oestrus-dependent alterations of bovine cervico-vaginal mucus glycosylation for potential as optimum fertilisation indicators 

    Le Berre, Marie; Gerlach, Jared Q.; Loughrey, Catherine; Creavin, Aileen; Pluta, Katarzyna; Gallagher, Mary; Carrington, Stephen D.; Joshi, Lokesh; Kilcoyne, Michelle (Royal Society of Chemistry, 2021-03-09)
    Oestrus is the period in the sexual cycle of female mammals during which ovulation occurs, where they become most receptive to mating and are most fertile. Efficient detection of oestrus is a key component in successful ...
  • Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia 

    Harold, Denise; Connolly, Siobhan; Riley, Brien P.; Kendler, Kenneth S.; McCarthy, Shane E.; McCombie, William R.; Richards, Alex; Owen, Michael J.; O'Donovan, Michael C.; Walters, James; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Donohoe, Gary; Gill, Michael; Corvin, Aiden; Morris, Derek W. (Wiley, 2019-02-23)
    Genome‐wide association studies (GWASs) are highly effective at identifying common risk variants for schizophrenia. Rare risk variants are also important contributors to schizophrenia etiology but, with the exception of ...
  • A decade to study deep-sea life. 

    Howell, Kerry L.; Hilário, Ana; Allcock, A. Louise; Bailey, David; Baker, Maria; Clark, Malcolm R.; Colaço, Ana; Copley, Jon; Cordes, Erik E.; Danovaro, Roberto; Dissanayake, Awantha; Escobar, Elva; Esquete, Patricia; Gallagher, Austin J.; Gates, Andrew R.; Gaudron, Sylvie M.; German, Christopher R.; Gjerde, Kristina M.; Higgs, Nicholas D.; Le Bris, Nadine; Levin, Lisa A.; Manea, Elisabetta; McClain, Craig; Menot, Lenaick; Mestre, Nelia C.; Metaxas, Anna; Milligan, Rosanna; Muthumbi, Agnes W. N.; Ramalho, Sofia P.; Ramirez-Llodra, Eva; Robson, Laura M.; Rogers, Alex D.; Sellanes, Javier; Sigwart, Julia D.; Sink, Kerry; Snelgrove, Paul V. R.; Stefanoudis, Paris V.; Sumida, Paulo Y; Taylor, Michelle L.; Thurber, Andrew R.; Vieira, Rui; Watanabe, Hiromi K.; Woodall, Lucy C.; Xavier, Joana R.; Narayanaswamy, Bhavani E. (Nature Research, 2020-11-25)
    The United Nations Decade of Ocean Science for Sustainable Development presents an exceptional opportunity to effect positive change in ocean use. We outline what is required of the deep-sea research community to achieve ...
  • The dairy biorefinery: Integrating treatment processes for cheese whey valorisation 

    Asunis, Fabiano; De Gioannis, Giorgia; Dessì, Paolo; Isipato, Marco; Lens, Piet N.L.; Muntoni, Aldo; Polettini, Alessandra; Pomi, Raffaella; Rossi, Andreina; Spiga, Daniela (Elsevier, 2020-08-28)
    With an estimated worldwide production of 190 billion kg per year, and due to its high organic load, cheese whey represents a huge opportunity for bioenergy and biochemicals production. Several physical, chemical and ...
  • Propionate production by bioelectrochemically-assisted lactate fermentation and simultaneous CO2 recycling 

    Isipato, Marco; Dessì, Paolo; Sánchez, Carlos; Mills, Simon; Ijaz, Umer Z.; Asunis, Fabiano; Spiga, Daniela; De Gioannis, Giorgia; Mascia, Michele; Collins, Gavin; Muntoni, Aldo; Lens, Piet N. L. (Frontiers Media, 2020-12-15)
    Production of volatile fatty acids (VFAs), fundamental building blocks for the chemical industry, depends on fossil fuels but organic waste is an emerging alternative substrate. Lactate produced from sugar-containing waste ...
  • Organic waste biorefineries: Looking towards implementation 

    Alibardi, Luca; Astrup, Thomas F.; Asunis, Fabiano; Clarke, William P.; De Gioannis, Giorgia; Dessì, Paolo; Lens, Piet N.L.; Lavagnolo, Maria Cristina; Lombardi, Lidia; Muntoni, Aldo; Pivato, Alberto; Polettini, Alessandra; Pomi, Raffaella; Rossi, Andreina; Spagni, Alessandro; Spiga, Daniela (Elsevier, 2020-07-16)
    The concept of biorefinery expands the possibilities to extract value from organic matter in form of either bespoke crops or organic waste. The viability of biorefinery schemes depends on the recovery of higher-value ...
  • Fermentative hydrogen production from cheese whey with in-line, concentration gradient-driven butyric acid extraction 

    Dessì P, Asunis F, Ravishankar H, Cocco FG, De Gioannis G, Muntoni A, Lens PNL; Dessì, Paolo; Asunis, Fabiano; Ravishankar, Harish; Cocco, Francesco Giuseppe; De Gioannis, Giorgia; Muntoni, Aldo; Lens, Piet N.L. (Elsevier, 2020-08-01)
    Hydrogen (H2) generation from cheese whey with simultaneous production and extraction of volatile fatty acids (VFAs) was studied in UASB reactors at two temperatures (20 and 35 °C) and pH values (5.0 and 4.5). The extraction ...
  • Microbial electrosynthesis: Towards sustainable biorefineries for production of green chemicals from CO2 emissions 

    Dessì, Paolo; Rovira-Alsina, Laura; Sánchez, Carlos; Dinesh, G. Kumaravel; Tong, Wenming; Chatterjee, Pritha; edesco, MicheleT; Farràs, Pau; Hamelers, Hubertus M.V.; Puig, Sebastià (Elsevier, 2020-12-01)
    Decarbonisation of the economy has become a priority at the global level, and the resulting legislative pressure is pushing the chemical and energy industries away from fossil fuels. Microbial electrosynthesis (MES) has ...
  • Carboxylic acids production and electrosynthetic microbial community evolution under different CO2 feeding regimes 

    Dessì, Paolo; Sánchez, Carlos; Mills, Simon; Cocco, Francesco Giuseppe; Isipato, Marco; Ijaz, Umer Z.; Collins, Gavin; Lens, Piet N.L. (Elsevier, 2020-10-15)
    Microbial electrosynthesis (MES) is a potential technology for CO2 recycling, but insufficient information is available on the microbial interactions underpinning electrochemically-assisted reactions. In this study, a MES ...
  • OpenTCC: An open source low-cost temperature-control chamber 

    Sánchez, Carlos; Dessì, Paolo; Duffy, Maeve; Lens, Piet N.L. (Elsevier, 2020-02-24)
    Microbial electrochemical technologies (MET) are emerging systems for environmental applications such as renewable energy production or pollution remediation. MET research often requires stable temperatures and low levels ...
  • The awarding of the first honorary Doctor of Science by the Queen's University in Ireland to William King – a journey of scientific curiosity 

    Murray, John; Dingsdale, Ann; Nasheuer, Heinz-Peter; Harper, David A.T. (Royal Irish Academy, 2020)
    William King (1809 86) was the founding Professor of Mineralogy and Geology at Queen s College Galway (QCG), one of three regional colleges opened in 1849 to provide secular university-level education in Ireland. King came ...
  • Inhibition of human BK polyomavirus replication by small noncoding RNAs 

    Tikhanovich, Irina; Liang, Bo; Seoighe, Cathal; Folk, William R.; Nasheuer, Heinz-Peter (American Society for Microbiology Journals, 2011)
    Small noncoding RNAs regulate a variety of cellular processes, including genomic imprinting, chromatin remodeling, replication, transcription, and translation. Here, we report small replication-regulating RNAs (srRNAs) ...
  • Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy 

    Broderick, Ronan; Ramadurai, Sivaramakrishnan; Tóth, Katalin; Togashi, Denisio M.; Ryder, Alan G.; Langowski, Jörg; Nasheuer, Heinz-Peter (Public Library of Science, 2012-04-19)
    Eukaryotic DNA replication is a dynamic process requiring the co-operation of specific replication proteins. We measured the mobility of eGFP-Cdc45 by Fluorescence Correlation Spectroscopy (FCS) in vivo in asynchronous ...
  • Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage 

    Broderick, Ronan; Rainey, Michael D.; Santocanale, Corrado; Nasheuer, Heinz-Peter (Wiley, 2013-08-02)
    The replication factor Cdc45 has essential functions in the initiation and elongation steps of eukaryotic DNA replication and plays an important role in the intra-S-phase checkpoint. Its interactions with other replication ...
  • Optimizing fluorescent protein expression for quantitative fluorescence microscopy and spectroscopy using herpes simplex thymidine kinase promoter sequences 

    Ali, Rizwan; Ramadurai, Sivaramakrishnan; Barry, Frank; Nasheuer, Heinz-Peter (Wiley, 2018-04-16)
    The modulation of expression levels of fluorescent fusion proteins (FFPs) is central for recombinant DNA technologies in modern biology as overexpression of proteins contributes to artifacts in biological experiments. In ...

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