Browsing Research Institutes and Centres by Author "http://dx.doi.org/10.13039/501100000781"
Now showing items 1-15 of 15
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Association of blood pressure lowering with incident dementia or cognitive impairment: A systematic review and meta-analysis
Hughes, Diarmaid; Judge, Conor; Murphy, Robert; Loughlin, Elaine; Costello, Maria; Whiteley, William; Bosch, Jackie; O'Donnell, Martin J.; Canavan, Michelle (American Medical Association (AMA), 2020-05-19)The benefit of blood pressure lowering for the prevention of dementia or cognitive impairment is unclear. To determine the association of blood pressure lowering with dementia or cognitive impairment. Search of PubMed, ... -
An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica.
Smith, David; Cwiklinski, Krystyna; Jewhurst, Heather; Tikhonova, Irina G.; Dalton, John P. (Nature Research, 2020-11-26)Fasciola hepatica is a global parasite of humans and their livestock. Regulation of parasite-secreted cathepsin L-like cysteine proteases associated with virulence is important to fine-tune parasite-host interaction. We ... -
Bi-Frequency Symmetry Difference (BFSD) EIT in stroke diagnosis
McDermott, Barry; O'Halloran, Martin; Porter, Emily (EIT2019, 2019-07-01)BFSD-EIT can detect deviations in the inherent normal symmetry of the head due to, for example, the presence of a bleed or clot in stroke. We assess the potential of BFSD-EIT to robustly detect lesions under a series of ... -
Bi-frequency symmetry difference EIT - feasibility and limitations of application to stroke diagnosis
McDermott, Barry; O'Halloran, Martin; Avery, James; Porter, Emily (Institute of Electrical and Electronics Engineers (IEEE), 2019-12-19)Objective: Bi-Frequency Symmetry Difference (BFSD)-EIT can detect, localize and identify unilateral perturbations in symmetric scenes. Here, we test the viability and robustness of BFSD-EIT in stroke diagnosis. Methods: A ... -
Bi-frequency symmetry difference electrical impedance tomography a novel technique for perturbation detection in static scenes
McDermott, Barry; Avery, James; O'Halloran, Martin; Aristovich, Kirill Y.; Porter, Emily (IOP Publishing, 2019-02-20)Objective: A novel method for the imaging of static scenes using Electrical Impedance Tomography (EIT) is reported with implementation and validation using numerical and phantom models. The technique is applicable to regions ... -
Brain haemorrhage detection through SVM classification of electrical impedance tomography measurements
McDermott, Barry; Dunne, Eoghan; O’Halloran, Martin; Porter, Emily; Santorelli, Adam (Springer, Cham, 2019-08-28)A brain haemorrhage constitutes a serious medical scenario with a need for rapid, accurate detection to facilitate treatment initiation. Machine learning (ML) techniques applied to such medical diagnostic problems can ... -
Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
Cwiklinski, Krystyna; Robinson, Mark W.; Donnelly, Sheila; Dalton, John P. (BMC, 2021-01-11)Background The major pathogenesis associated with Fasciola hepatica infection results from the extensive tissue damage caused by the tunnelling and feeding activity of immature flukes during their migration, growth and ... -
Diagnosis of sheep fasciolosis caused by Fasciola hepatica using cathepsin L enzyme-linked immunosorbent assays (ELISA)
López Corrales, Jesús; Cwiklinski, Krystyna; De Marco Verissimo, Carolina; Dorey, Amber; Lalor, Richard; Jewhurst, Heather; McEvoy, Amanda; Diskin, Michael; Duffy, Catherine; Cosby, S Louise; Keane, Orla M; Dalton, John Pius (Elsevier, 2021-07-13)Fasciolosis, a global parasitic disease of agricultural livestock, is caused by the liver fluke Fasciola hepatica. Management and strategic control of fasciolosis on farms depends on early assessment of the extent of disease ... -
Dielectric properties of bones for the monitoring of osteoporosis
Amin, Bilal; Elahi, Muhammad Adnan; Shahzad, Atif; Porter, Emily; McDermott, Barry; O’Halloran, Martin (Springer, 2018-08-29)Osteoporosis is one of the most common diseases that leads to bone fractures. Dual-energy X-ray absorptiometry is currently employed to measure the bone mineral density and to diagnose osteoporosis. Alternatively, the ... -
Electric field stimulation for tissue engineering applications
Ryan, Christina N. M.; Doulgkeroglou, Meletios N.; Zeugolis, Dimitrios I. (BMC (part of Springer Nature), 2021-01-05)Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric field stimulation ... -
An empirical dielectric mixing model for biological tissues
Salahuddin, Saqib; McDermott, Barry; Porter, Emily; O’Halloran, Martin; Elahi, Muhammad Adnan; Shahzad, Atif (IEEE, 2019-03-31)Dielectric properties of biological tissues are critically important for various electromagnetic based medical therapeutic and diagnostic technologies. This paper attempts to develop an empirical dielectric mixture model ... -
Linear regression for estimating bladder volume with voltage signals
Dunne, Eoghan; Santorelli, Adam; McGinley, Brian; O'Halloran, Martin; Porter, Emily (IEEE, 2018-11-08)Urinary incontinence is a common condition that can severely impact the lives of those who have it. Bladder volume monitoring solutions that exploit the electrical differences of different tissues in the pelvis have the ... -
Microwave ablation antenna for functional adenomas in the adrenal gland
Farina, Laura; de Marco, A. J.; Bottiglieri, Anna; Ruvio, Giuseppe; Eaton-Evans, Jimmy; Dennedy, Michael C.; Elahi, Adnan; O’Halloran, Martin (IEEE, 2020-03-02)Microwave thermal ablation has been thoroughly investigated in the last decades. However, new challenges for this technology are nowadays represented by specific applications. The present work investigates a promising ... -
Monitoring microwave thermal ablation using electrical impedance tomography: an experimental feasibility study
Bottiglieri, Anna; Dunne, Eoghan; McDermott, Barry; Cavagnaro, Marta; Porter, Emily; Farina, Laura (IEEE, 2020)Low-cost and reliable methods for monitoring the size of the ablation zone during microwave thermal ablation (MTA) are crucial in the oncological clinical practice. The aim of this work is to test the performance of ... -
Multiclass SVM for bladder volume monitoring using electrical impedance measurements
Santorelli, Adam; Dunne, Eoghan; Porter, Emily; O'Halloran, Martin (IEEE, 2018-11-08)Urinary incontinence is a common condition that impacts the quality of life from those who suffer from it. Electrical impedance measurements offer the potential for a non-invasive low-cost solution to monitor changes in ...