Electric field stimulation for tissue engineering applications
Date
2021-01-05Author
Ryan, Christina N. M.
Doulgkeroglou, Meletios N.
Zeugolis, Dimitrios I.
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Ryan, Christina N. M., Doulgkeroglou, Meletios N., & Zeugolis, Dimitrios I. (2021). Electric field stimulation for tissue engineering applications. BMC Biomedical Engineering, 3(1), doi:10.1186/s42490-020-00046-0
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Abstract
Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric field stimulation as a biophysical environmental cue for organised tissue engineering strategies various electric field stimulation systems have been developed. These systems are overall similar in design and have been shown to influence morphology, orientation, migration and phenotype of several different cell types. This review discusses different electric field stimulation setups and their effect on cell response.