Research Institutes and Centres
Browse by
Sub-communities within this community
Recent Submissions
-
Automation, monitoring, and standardization of cell product manufacturing
(Frontiers Media, 2020-07-14)Although regenerative medicine products are at the forefront of scientific research, technological innovation, and clinical translation, their reproducibility and large-scale production are compromised by automation, ... -
Electric field stimulation for tissue engineering applications
(BMC (part of Springer Nature), 2021-01-05)Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric field stimulation ... -
Family support and the media in Ireland: Newspaper content analysis 2014–2017
(Routledge, 2021-01-15)The objective of this paper is to inform a critical analysis of how the media portray family support in Ireland. Findings of a content analysis carried out on national and regional Irish newspapers between 2014 and 2017 ... -
Uncovering semantic bias in neural network models using a knowledge graph
(ACM, 2020-10-19)While neural networks models have shown impressive performance in many NLP tasks, lack of interpretability is often seen as a disadvantage. Individual relevance scores assigned by post-hoc explanation methods are not ... -
The data ethics challenges of explainable AI and their knowledge-based solutions
(IOS Press, 2020-05)Abstract. Explainable AI has recently gained momentum as an approach to overcome some of the more obvious ethical implications of the increasingly widespread application of AI (mostly machine learning). It is however not ... -
Morphological and molecular assessments of bobtail squids (Cephalopoda: Sepiolidae) reveal a hidden history of biodiversity
(Frontiers Media, 2021-01-20)Molecular species delimitation assists taxonomic decisions for challenging species, like cryptic species complexes. Bobtail squids (Family Sepiolidae Leach, 1817) are a very diverse group of benthic and nektonic small to ... -
Adoption Rights Alliance, JFM Research, Clann Project Briefing Notes re. the Final Report of the Mother and Baby Homes Commission of Investigation
(Clann Project, 2021)On Tuesday 12 January 2021, the Irish Government will publish the Report of the Mother and Baby Homes Commission of Investigation (MBHCOI). The Government has stated that the Report is 3,000-4,000 pages long. We will be ... -
The motivational factors and adverse events experienced by healthy volunteers donating bone marrow for research
(Heighten Science Publications Corporation (HSPC), 2019-12-05)Background: With the advancement of cell therapy research, there is an increasing need for healthy volunteers (HV) to donate small volumes (30 ml) of human bone marrow (BM). The BM procedure required to procure small ... -
Exploring the innate human potential for positive adaptation in the ace of impending mortality: Is there a response shift in subjective quality of life over time in a group of patients with lung cancer receiving palliative treatment?
(International Journal of Innovative Research in Medical Science, 2020-05-06)Traditionally changes in quality of life (QoL) are assessed using self report questionnaires. They rely on the assumption that the patient’s point of reference does not change over time. However in reality patients with ... -
A guide to selecting a measurement tool for quality of life assessment
(Medical and Clinical Research, 2019-05-07)Modern approaches to patient treatment and personalized medicine increasingly recognize the importance of the patient’s quality of life outcome. The art of assessing and using quality of life information in routine practice ... -
An intervention using quality of life and symptom information as a clinical tool in patients with advanced cancer
(International Journal of Innovative Research in Medical Science (IJIRMS), 2019-09-07)The Schedule for Evaluation of Individual Quality of Life-Direct Weighting (SEIQoL-DW) recognizes the individuals’ values with no pre-judgement. The objective of this study was to determine if clinician awareness and ... -
‘Count me in’: The Irish Research Nurse Network (IRNN) national clinical research nurse/midwife workforce survey
(Royal College of Surgeons Ireland, 2019-08)[No Abstract availabl] -
Synergy between embedding and protein functional association networks for drug label prediction using harmonic function
(ACM and IEEE, 2020-10-16)Semi-Supervised Learning (SSL) is an approach to machine learning that makes use of unlabeled data for training with a small amount of labeled data. In the context of molecular biology and pharmacology, one can take advantage ... -
Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers
(BMC, 2019-11-19)Background: Renal proximal tubular epithelial cells (RPTEC) are dysfunctional in diabetic kidney disease (DKD). Mesenchymal stromal cells (MSC) may modulate DKD pathogenesis through anti-inflammatory mediators. This study ... -
Plasma dephosphorylated-uncarboxylated Matrix Gla-Protein (dp-ucMGP): reference intervals in Caucasian adults and diabetic kidney disease biomarker potential
(Nature Research, 2019-12-05)Recent studies suggest a possible association between dephosphorylated-uncarboxylated MGP (dp-ucMGP) and glomerular filtration rate (GFR). This study aimed to establish normative data in an adult Caucasian population and ... -
Saving lives and saving the planet: The readiness of Ireland's healthcare manufacturing sector for the circular economy
(Springer, 2020-09-11)Healthcare manufacturing is one of the leading creators of single-use products in Ireland and accounts for 11% of waste generated. Industry and businesses can play a significant role in tackling unsustainable production ... -
Increased weight gain during the long interdialytic period Is associated with minor effects on blood pressure control in clinically stable in-centre haemodialysis patients
(Karger Publishers, 2018-11-09)Background/Aims: Three-day-a-week chronic haemodialysis (cHD) involves 1 long (72 h) and 2 short (48 h) inter-dialytic periods (IDPs), We aimed to determine whether BP control following the long IDP is inferior to the short ... -
Mesenchymal stromal cell–based therapies for acute kidney injury: progress in the last decade
(Elsevier, 2020-01-28)A little over 10 years ago, the therapeutic potential of mesenchymal stromal cells (MSCs) for the treatment of acute kidney injury (AKI) was becoming widely recognized. Since then, there has been further intensive study ... -
Editorial: Innovative biologics and drugs to target renal inflammation
(Frontiers Media, 2020-02-06)[No abstract available] -
Effects of mesenchymal stromal cells on regulatory T cells: Current understanding and clinical relevance
(AlphaMed Press and Wiley, 2020-01-29)The immunomodulatory potential of mesenchymal stromal cells (MSCs) and regulatory T cells (T-reg) is well recognized by translational scientists in the field of regenerative medicine and cellular therapies. A wide range ...