Browsing Medicine (Scholarly Articles) by Title

Now showing items 42-61 of 91

    • Impact of ultra-short pauses between stacked lesions with and without active esophageal cooling 

      Mercado Montoya, Marcela; Gomez Bustamante, Tatiana; Berjano, Enrique; Mickelsen, Steven R.; Hernandez Arango, Pablo; González Suárez, Ana; Schieber, Jay; Kulstad, Erik; Daniels, James D. (Oxford University Press, 2023-05-24)
      Background Placing lesions at the same point (stacking lesions) in the left atrium during radiofrequency (RF) ablation can increase the risk of collateral injury. The use of active esophageal cooling has been shown to ...

    • Indistinguishable NDM-producing escherichia coli isolated from recreational waters, sewage, and a clinical specimen in Ireland, 2016 to 2017 

      Mahon, Bláthnaid M.; Brehony, Carina; McGrath, Elaine; Killeen, James; Cormican, Martin; Hickey, Paul; Keane, Shane; Hanahoe, Belinda; Dolan, Ann; Morris, Dearbháile (European Centre for Disease Prevention and Control, 2017-04-13)
      In this study, New Delhi metallo-beta-lactamase (NDM)-producing Enterobacteriaceae were identified in Irish recreational waters and sewage. Indistinguishable NDM-producing Escherichia coli by pulsed-field gel electrophoresis ...

    • Integrated analyses of microbiome and longitudinal metabolome data reveal microbial-host interactions on sulfur metabolism in Parkinson's disease. 

      Hertel, Johannes; Harms, Amy C.; Heinken, Almut; Baldini, Federico; Thinnes, Cyrille C; Glaab, Enrico; Vasco, Daniel A.; Pietzner, Maik; Stewart, Isobel D.; Wareham, Nicholas J.; Langenberg, Claudia; Trenkwalder, Claudia; Krüger, Rejko; Hankemeier, Thomas; Fleming, Ronan M. T.; Mollenhauer, Brit; Thiele, Ines (Elsevier, 2019-11-12)
      Parkinson's disease (PD) exhibits systemic effects on the human metabolism, with emerging roles for the gut microbiome. Here, we integrate longitudinal metabolome data from 30 drug-naive, de novo PD patients and 30 matched ...

    • Integrated in vitro and in silico modelling delineates the molecular effects of a synbiotic regimen on colorectal cancer-derived cells 

      Greenhalgh, Kacy; Ramiro-Garcia, Javier; Heinken, Almut; Ullmann, Pit; Bintener, Tamara; Pires Pacheco, Maria; Baginska, Joanna; Shah, Pranjul; Frachet, Audrey; Halder, Rashi; Fritz, Joëlle V.; Sauter, Thomas; Thiele, Ines; Haan, Serge; Letellier, Elisabeth; Wilmes, Paul (Cell Press, 2019-04-30)
      By modulating the human gut microbiome, prebiotics and probiotics (combinations of which are called synbiotics) may be used to treat diseases such as colorectal cancer (CRC). Methodological limitations have prevented ...

    • Interns and their smartphones: use for clinical practice 

      O'Connor, Paul; Byrne, Darra; Butt, M.; Lydon, S.; Stewart, Brian; Kerin, M. J. (Medscape, 2014)
      Purpose of the study Smartphone use among healthcare professionals has become widespread and will continue to grow in the coming years.Study design In October 2012, a survey was distributed to 230 interns at two of the ...

    • Investigating the management of diabetes in nursing homes using a mixed methods approach 

      Hurley, Lorna; O'Donnell, Máire; Ó Caoimh, Ronan; Dinneen, Seán F. (Elsevier ScienceDirect, 2017-03-21)
      Aims: As populations age there is an increased demand for nursing home (NH) care and a parallel increase in the prevalence of diabetes. Despite this, there is growing evidence that the management of diabetes in NHs is ...

    • The Irish DAFNE Study Protocol: A cluster randomised trial of group versus individual follow-up after structured education for Type 1 diabetes 

      Dinneen, Seán F.; O' Hara, Mary Clare; Byrne, Molly; Newell, John; Daly, Lisa (2009)
      Background: Structured education programmes for individuals with Type 1 diabetes have become a recognised means of delivering the knowledge and skills necessary for optimal self-management of the condition. The Dose ...

    • Is diabetes self-management education still the Cinderella of diabetes care? 

      Hurley, Lorna; O’Donnell, Máire; O’Hara, Mary Clare; Carey, Marian E.; Willaing, Ingrid; Daly, Heather; Dinneen, Seán F. (Elsevier ScienceDirect, 2017-05-17)
      This paper reflects on the status of diabetes self-management education (DSME) as a branch of diabetology in Europe and discusses some opportunities for better supporting DSME delivery. DSME (also commonly known as Therapeutic ...

    • Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study 

      O’Donnell, Martin; Mente, Andrew; Rangarajan, Sumathy; McQueen, Matthew J.; O’Leary, Neil; Yin, Lu; Liu, Xiaoyun; Swaminathan, Sumathi; Khatib, Rasha; Rosengren, Annika; Ferguson, John; Smyth, Andrew; PURE Investigators (BMJ Publishing Group, 2019-03-13)
      Abstract Objective To evaluate the joint association of sodium and potassium urinary excretion (as surrogate measures of intake) with cardiovascular events and mortality, in the context of current World Health Organization ...

    • Linguistic and Psychometric Validation of the Diabetes-Specific Quality-of-Life Scale in UK English for Adults With Type 1 Diabetes 

      O' Hara, Mary Clare; Dinneen, Sean (American Diabetes Association, 2012-12-18)
      OBJECTIVE-To develop a linguistically and psychometrically validated U.K. English (U.K.! Ireland) version of the Diabetes-Specific Quality-of-Life Scale (DSQOLS) for adults with type 1 diabetes.RESEARCH DESIGN AND METHODS-We ...

    • Lipid lowering therapy, low-density lipoprotein level and risk of intracerebral hemorrhage – a meta-analysis 

      Judge, Conor; Ruttledge, Sarah; Costello, Maria; Murphy, Robert; Loughlin, Elaine; Alvarez-Iglesias, Alberto; Ferguson, John; Gorey, Sarah; Nolan, Aoife; Canavan, Michelle; O'Halloran, Martin; O'Donnell, Martin J. (Elsevier, 2019-03-14)
      The association of lipid lowering therapy and intracerebral hemorrhage risk is controversial. We performed a cumulative meta-analysis of lipid lowering trials that reported intracerebral hemorrhage. Statin, fibrate, ...

    • A longitudinal qualitative study examining the factors impacting on the ability of persons with T1DM to assimilate the Dose Adjustment For Normal Eating (DAFNE) principles into daily living and how these factors change over time 

      Murphy, Kathy; Casey, Dympna; Dinneen, Sean (BioMed Central, 2011-08-30)
      The literature reveals that structured education programmes, such as DAFNE, result in many positive outcomes for people with Type 1 diabetes including a decrease in HbA1c levels and reductions in hypoglycaemia. While there ...

    • A longitudinal survey of antibiotic-resistant enterobacterales in the Irish environment, 2019–2020 

      Hooban, Brigid; Fitzhenry, Kelly; O'Connor, Louise; Miliotis, Georgios; Joyce, Aoife; Chueiri, Alexandra; Farrell, Maeve Louise; DeLappe, Niall; Tuohy, Alma; Cormican, Martin; Morris, Dearbháile (Elsevier, 2022-03-17)
      The natural environment represents a complex reservoir of antibiotic-resistant bacteria as a consequence of different wastewater discharges including anthropogenic and agricultural. Therefore, the aim of this study was to ...

    • Low-frequency electrical conductivity of trabecular bone: Insights from in silico modeling 

      Cervantes, María José; Basiuk, Lucas O.; González-Suárez, Ana; Carlevaro, C. Manuel; Irastorza, Ramiro M.; María José Cervantes (MDPI, 2023-09-23)
      Background: The electrical conductivity of trabecular bone at 100 kHz has recently been reported as a good predictor of bone volume fraction. However, quantifying its relationship with free water (or physiological solution) ...

    • The maternal and fetal impacts of obesity and gestational diabetes on pregnancy outcome 

      Dennedy, Michael Conall; Dunne, Fidelma (2010)
      Obesity has reached pandemic proportions and is of growing concern worldwide. Adverse health outcomes associated with a raised body mass index present the greatest challenge currently facing clinicians across all ...

    • Medical speciality choices: Does personality matter? 

      O'Connor, Paul (Irish Medical Journal, 2015-08-07)
      There has been increasing interest in the personalities of doctors. This study examined whether personality differed based upon gender, level of training or medical speciality among 200 physicians and 134 medical students. ...

    • Mesenchymal stem cell therapy to promote corneal allograft survival: current status and pathway to clinical translation 

      Murphy, Nick; Lynch, Kevin; Lohan, Paul; Treacy, Oliver; Ritter, Thomas (Lippincott, Williams & Wilkins, 2016-12)
      PURPOSE OF REVIEW: This article reviews the literature on the therapeutic potential of mesenchymal stem cells (MSCs) to prolong corneal allograft survival. RECENT FINDINGS: To date, only small numbers studies have ...

    • A meta-analysis of the effectiveness of crew resource management training in acute care domains. 

      O'Dea, Angela; O'Connor, Paul; Keogh, Ivan (2014)
      The healthcare industry has seen an increase in the adoption of team training, such as crew resource management (CRM), to improve teamwork and coordination within acute care medical teams. A meta-analysis was carried out ...

    • Minimum information about T Regulatory Cells: A step toward reproducibility and standardization 

      Fuchs, Anke; Gliwinski, Mateusz; Grageda, Nathali; Spiering, Rachel; Abbas, Abul K.; Appel, Silke; Bacchetta, Rosa; Battaglia, Manuela; Berglund, David; Blazar, Bruce; Bluestone, Jeffrey A.; Bornhaeuser, Martin; ten Brinke, Anja; Brusko, Todd M.; Cools, Nathalie; Cuturi, Maria Cristina; Geissler, Edward; Giannoukakis, Nick; Golab, Karolina; Hafler, David A.; van Ham, S. Marieke; Hester, Joanna; Hippen, Keli; Di Ianni, Mauro; Ilic, Natasa; Isaacs, John; Issa, Fadi; Iwaszkiewicz-Grzes, Dorota; Jaeckel, Elmar; Joosten, Irma; Klatzmann, David; Koenen, Hans; van Kooten, Cees; Korsgren, Olle; Kretschmer, Karsten; Levings, Megan; Marek-Trzonkowska, Natalia Maria; Martinez-Llordella, Marc; Miljkovic, Djordje; Mills, Kingston H. G.; Miranda, Joana P.; Piccirillo, Ciriaco A.; Putnam, Amy L.; Ritter, Thomas; Roncarolo, Maria Grazia; Sakaguchi, Shimon; Sanchez-Ramon, Silvia; Sawitzki, Birgit; Sofronic-Milosavljevic, Ljiljana; Sykes, Megan; Tang, Qizhi; Vives-Pi, Marta; Waldmann, Herman; Witkowski, Piotr; Wood, Kathryn J.; Gregori, Silvia; Hilkens, Catharien M. U.; Lombardi, Giovanna; Lord, Phillip; Martinez-Caceres, Eva M.; Trzonkowski, Piotr (Frontiers Media, 2018-01-15)
      Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing ...

    • Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies 

      Lord, Philip; Spiering, Rachel; Aguillon, Juan C.; Anderson, Amy E.; Appel, Silke; Benitez-Ribas, Daniel; ten Brinke, Anja; Broere, Femke; Cools, Nathalie; Cuturi, María Cristina; Diboll, Julie; Geissler, Edward; Giannoukakis, Nick; Gregori, Silvia; van Ham, Sija Marieke; Lattimer, Staci; Marshall, Lindsay F.; Harry, Rachel A.; Hutchinson, James A.; Isaacs, John D.; Joosten, Irma; van Kooten, Cees; de Cerio, Ascensión López Díaz; Nikolic, Tatjana; Oral, Haluk Barbaros; Sofronic-Milosavljevic, Ljiljana; Ritter, Thomas; Riquelme, Paloma; Thomson, Angus W.; Trucco, Massimo; Vives-Pi, Marta; Martinez-Caceres, Eva M.; Hilkens, Catharien M.U. (PeerJ, 2016-08-30)
      Cellular therapies, with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation The methodologies ...