Recent Submissions

  • Extracellular vesicles as modulators of wound healing 

    Cabral, Joana; Ryan, Aideen E.; Griffin, Matthew D.; Ritter, Thomas (Elsevier, 2018-01-31)
    Impaired healing of cutaneous wounds and ulcers continues to have a major impact on the quality of life of millions of people. In recent years, the capacity for stem and progenitor cells to promote wound repair has been ...
  • Minimum information about T Regulatory Cells: A step toward reproducibility and standardization 

    Fuchs, Anke; Gliwinski, Mateusz; Grageda, Nathali; Spiering, Rachel; Abbas, Abul K.; Appel, Silke; Bacchetta, Rosa; Battaglia, Manuela; Berglund, David; Blazar, Bruce; Bluestone, Jeffrey A.; Bornhaeuser, Martin; ten Brinke, Anja; Brusko, Todd M.; Cools, Nathalie; Cuturi, Maria Cristina; Geissler, Edward; Giannoukakis, Nick; Golab, Karolina; Hafler, David A.; van Ham, S. Marieke; Hester, Joanna; Hippen, Keli; Di Ianni, Mauro; Ilic, Natasa; Isaacs, John; Issa, Fadi; Iwaszkiewicz-Grzes, Dorota; Jaeckel, Elmar; Joosten, Irma; Klatzmann, David; Koenen, Hans; van Kooten, Cees; Korsgren, Olle; Kretschmer, Karsten; Levings, Megan; Marek-Trzonkowska, Natalia Maria; Martinez-Llordella, Marc; Miljkovic, Djordje; Mills, Kingston H. G.; Miranda, Joana P.; Piccirillo, Ciriaco A.; Putnam, Amy L.; Ritter, Thomas; Roncarolo, Maria Grazia; Sakaguchi, Shimon; Sanchez-Ramon, Silvia; Sawitzki, Birgit; Sofronic-Milosavljevic, Ljiljana; Sykes, Megan; Tang, Qizhi; Vives-Pi, Marta; Waldmann, Herman; Witkowski, Piotr; Wood, Kathryn J.; Gregori, Silvia; Hilkens, Catharien M. U.; Lombardi, Giovanna; Lord, Phillip; Martinez-Caceres, Eva M.; Trzonkowski, Piotr (Frontiers Media, 2018-01-15)
    Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing ...
  • Anti-donor immune responses elicited by allogeneic mesenchymal stem cells and their extracellular vesicles: Are we still learning? 

    Lohan, Paul; Treacy, Oliver; Griffin, Matthew D.; Ritter, Thomas; Ryan, Aideen E. (Frontiers Media, 2017-11-24)
    Mesenchymal stromal cells (MSC) have been used to treat a broad range of disease indications such as acute and chronic inflammatory disorders, autoimmune diseases, and transplant rejection due to their potent immunosuppr ...
  • Strength in Numbers: an international consensus conference to develop a novel approach to care delivery for young adults with type 1 diabetes, the D1 Now Study 

    O'Hara, Mary Clare; Hynes, L.; O'Donnell, M.; Keighron, C.; Allen, G.; Caulfield, A.; Duffy, C.; Long, M.; Mallon, M.; Mullins, M.; Tonra, G.; Byrne, Molly; Dinneen, Seán F. (BioMed Central, 2017-12-04)
    Many young adults with type 1 diabetes struggle with the day-to-day management of their condition. They often find it difficult to find the time to attend their clinic appointments and to meet with their diabetes healthcare ...
  • vIL-10-overexpressing human MSCs modulate naïve and activated T lymphocytes following induction of collagenase-induced osteoarthritis 

    Farrell, Eric; Fahy, Niamh; Ryan, Aideen E.; O Flatharta, Cathal; O'Flynn, Lisa; Ritter, Thomas; Murphy, J. Mary; Farrell, Eric; Fahy, Niamh (2016-05-18)
    Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression. We sought to establish the in-vivo immune response in collagenase-induced ...
  • Regulating immunogenicity and tolerogenicity of bone marrow-derived dendritic cells through modulation of cell surface glycosylation by dexamethasone treatment 

    Lynch, Kevin; Treacy, Oliver; Gerlach, Jared Q.; Annuk, Heidi; Lohan, Paul; Cabral, Joana; Joshi, Lokesh; Ryan, Aideen E.; Ritter, Thomas (Frontiers Media, 2017-10-30)
    Dendritic cellular therapies and dendritic cell vaccines show promise for the treatment of autoimmune diseases, the prolongation of graft survival in transplantation, and in educating the immune system to fight cancers. ...
  • Free water elimination and mapping from diffusion tensor imaging (DTI) in chronic schizophrenia 

    Colgan, Niall; O'Reilly, David; Holleran, Laurena; Ahmed, Mohamed; McDonald, Colm; Cannon, Dara M. (NUI Galway, 2017-06-11)
    Diffusion tensor imaging (DTI) acquisitions allows the comparison of diffusion characteristics in vivo and gives a unique insight into tissue structure and pathology. However, a limitation of DTI post-processing is the ...
  • Investigating the management of diabetes in nursing homes using a mixed methods approach 

    Hurley, Lorna; O'Donnell, Máire; Ó Caoimh, Ronan; Dinneen, Seán F. (Elsevier ScienceDirect, 2017-03-21)
    Aims: As populations age there is an increased demand for nursing home (NH) care and a parallel increase in the prevalence of diabetes. Despite this, there is growing evidence that the management of diabetes in NHs is ...
  • Is diabetes self-management education still the Cinderella of diabetes care? 

    Hurley, Lorna; O’Donnell, Máire; O’Hara, Mary Clare; Carey, Marian E.; Willaing, Ingrid; Daly, Heather; Dinneen, Seán F. (Elsevier ScienceDirect, 2017-05-17)
    This paper reflects on the status of diabetes self-management education (DSME) as a branch of diabetology in Europe and discusses some opportunities for better supporting DSME delivery. DSME (also commonly known as Therapeutic ...
  • Structural connectivity and rich-club organization in recent onset psychosis 

    Forcellini, Giulia; O'Donoghue, Stefani; Kenney, Joanne; McInerney, Shane; Scanlon, Cathy; Nabulsi, Leila; McPhilemy, Genevieve; Kilmartin, Liam; O'Hora, Denis; Hallahan, Brian; Cannon, Dara M.; McDonald, Colm (Elsevier, 2017-05-17)
    [No abstract available]
  • Indistinguishable NDM-producing escherichia coli isolated from recreational waters, sewage, and a clinical specimen in Ireland, 2016 to 2017 

    Mahon, Bláthnaid M.; Brehony, Carina; McGrath, Elaine; Killeen, James; Cormican, Martin; Hickey, Paul; Keane, Shane; Hanahoe, Belinda; Dolan, Ann; Morris, Dearbháile (European Centre for Disease Prevention and Control, 2017-04-13)
    In this study, New Delhi metallo-beta-lactamase (NDM)-producing Enterobacteriaceae were identified in Irish recreational waters and sewage. Indistinguishable NDM-producing Escherichia coli by pulsed-field gel electrophoresis ...
  • Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies 

    Lord, Philip; Spiering, Rachel; Aguillon, Juan C.; Anderson, Amy E.; Appel, Silke; Benitez-Ribas, Daniel; ten Brinke, Anja; Broere, Femke; Cools, Nathalie; Cuturi, María Cristina; Diboll, Julie; Geissler, Edward; Giannoukakis, Nick; Gregori, Silvia; van Ham, Sija Marieke; Lattimer, Staci; Marshall, Lindsay F.; Harry, Rachel A.; Hutchinson, James A.; Isaacs, John D.; Joosten, Irma; van Kooten, Cees; de Cerio, Ascensión López Díaz; Nikolic, Tatjana; Oral, Haluk Barbaros; Sofronic-Milosavljevic, Ljiljana; Ritter, Thomas; Riquelme, Paloma; Thomson, Angus W.; Trucco, Massimo; Vives-Pi, Marta; Martinez-Caceres, Eva M.; Hilkens, Catharien M.U. (PeerJ, 2016-08-30)
    Cellular therapies, with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation The methodologies ...
  • Mesenchymal stem cell therapy to promote corneal allograft survival: current status and pathway to clinical translation 

    Murphy, Nick; Lynch, Kevin; Lohan, Paul; Treacy, Oliver; Ritter, Thomas (Lippincott, Williams & Wilkins, 2016-12)
    PURPOSE OF REVIEW: This article reviews the literature on the therapeutic potential of mesenchymal stem cells (MSCs) to prolong corneal allograft survival. RECENT FINDINGS: To date, only small numbers studies have ...
  • Application of video-based methods for competitive swimming analysis: a systematic review 

    Quinlan, Leo; Ó Laighin, Gearóid; Mooney, Robert; Corley, Gavin (2015)
    This paper explores the application of video-based methods for the analysis of com- petitive swimming performance. A systematic search of the existing literature was conducted using the following keywords: swim*, performance, ...
  • Signaling pathways in mouse embryo stem cell self-renewal 

    Quinlan, Leo (In Tech, 2011)
    At the pre-implantation blastocyst stage of development, the mammalian embryo is composed of a unique collection of cells of which three major populations predominate. The outermost layer the trophectoderm (TE) gives ...
  • Medical speciality choices: Does personality matter? 

    O'Connor, Paul (Irish Medical Journal, 2015-08-07)
    There has been increasing interest in the personalities of doctors. This study examined whether personality differed based upon gender, level of training or medical speciality among 200 physicians and 134 medical students. ...
  • Distribution of tract deficits in schizophrenia 

    Cannon, Dara (BioMed Central, 2014-04-02)
    Background: Gray and white matter brain changes have been found in schizophrenia but the anatomical organizing process underlying these changes remains unknown. We aimed to identify gray and white matter volumetric changes ...
  • Gender-specific abnormalities in the serotonin transporter system in panic disorder 

    Cannon, Dara (Cambridge University Press, 2013)
    The central serotonergic system has been implicated in the pathophysiology of panic disorder (PD) by evidence of abnormally elevated serotonin-turnover, reduced pre- and post-synaptic 5-HT(1A-)receptor sensitivity and ...
  • Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [C-11]DASB 

    Cannon, Dara (2010)
    In a previous study we showed that genetic variation in HTR2A, which encodes the serotonin 2A receptor, influenced outcome of citalopram treatment in patients with major depressive disorder. Since chronic administration ...
  • Curriculum development for sustainable civic engagement 

    Boland, Josephine (Educational Developers of Ireland Network, 2013)
    Capacity building both for students and for community partners is an explicit goal for one particular teaching and learning innovation in Irish higher education. In addition to offering the opportunity to apply ...

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