Browsing Medicine (Scholarly Articles) by Issue Date
Now showing items 1-20 of 79
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Effects of Gamma Irradiation and Pasteurization on the Nutritive Composition of Commercially Available Animal Diets
(2008)Gamma radiation is used to sterilize diets for specific pathogen-free (SPF) animals. Because a gamma-irradiated diet was linked to leukoencephalomyelopathy in SPF cats, we investigated the effects of 'typical' (28.9-34.3 ... -
The Irish DAFNE Study Protocol: A cluster randomised trial of group versus individual follow-up after structured education for Type 1 diabetes
(2009)Background: Structured education programmes for individuals with Type 1 diabetes have become a recognised means of delivering the knowledge and skills necessary for optimal self-management of the condition. The Dose ... -
ATLANTIC DIP: pregnancy outcome for women with pregestational diabetes along the Irish Atlantic seaboard.
(2009)OBJECTIVE Prospective evaluation of pregnancy outcomes in pregestational diabetes along the Atlantic seaboard 2006¿2007. RESEARCH DESIGN AND METHODS The Atlantic Diabetes in Pregnancy group, representing five antenatal ... -
Teaching and learning through civic engagement: prospects for sustainability in teacher education
(2010)This paper considers the prospects for sustainable service/community based learning as an element of a civic engagement strategy within the context of teacher education. It draws on findings of a study of the policy, ... -
Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [C-11]DASB
(2010)In a previous study we showed that genetic variation in HTR2A, which encodes the serotonin 2A receptor, influenced outcome of citalopram treatment in patients with major depressive disorder. Since chronic administration ... -
The maternal and fetal impacts of obesity and gestational diabetes on pregnancy outcome
(2010)Obesity has reached pandemic proportions and is of growing concern worldwide. Adverse health outcomes associated with a raised body mass index present the greatest challenge currently facing clinicians across all ... -
Antimicrobial management and appropriateness of treatment of urinary tract infection in general practice in Ireland
(2011)ABSTRACT: BACKGROUND: Urinary tract infections (UTIs) are the second most common bacterial infections in general practice and a frequent indication for prescription of antimicrobials. Increasing concern about the association ... -
Participants' perceptions of the factors that influence Diabetes Self-Management Following a Structured Education (DAFNE) programme
(Wiley, 2011-04-15)Aim.The aim of this study was to understand the experience of participants in the Dose Adjustment for Normal Eating programme and to identify factors that influence participants' implementation of the self-management ... -
Identifying and addressing the limitations of safety climate surveys.
(Elsevier, 2011-06)This paper reports the descriptive analysis of a large sample of safety climate survey data (n = 110,014) collected over 10 years from U.S. Naval aircrew using the Command Safety Assessment Survey (CSAS). -
A longitudinal qualitative study examining the factors impacting on the ability of persons with T1DM to assimilate the Dose Adjustment For Normal Eating (DAFNE) principles into daily living and how these factors change over time
(BioMed Central, 2011-08-30)The literature reveals that structured education programmes, such as DAFNE, result in many positive outcomes for people with Type 1 diabetes including a decrease in HbA1c levels and reductions in hypoglycaemia. While there ... -
Effects of arterial cannulation stress on regional cerebral blood flow in major depressive disorder
(Nature Publishing Group, 2012)Individuals with major depressive disorder (MDD) display abnormal neurophysiological responses to psychological stress but little is known about their neurophysiological responses to physiological stressors. Using [O-15]-H2O ... -
Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the rat hypothalamus following an immunological stressor
(2012)The endocannabinoid system is an important regulator of the nervous, neuroendocrine and immune systems, thus representing a novel therapeutic target for stress-related neuroinflammatory and psychiatric disorders. However, ... -
The association of white matter volume in psychotic disorders with genotypic variation in NRG1, MOG and CNP: a voxel-based analysis in affected individuals and their unaffected relatives
(Nature Publishing Group, 2012)We investigated the role of variation in putative psychosis genes coding for elements of the white matter system by examining the contribution of genotypic variation in three single-nucleotide polymorphisms (SNPs) neuregulin ... -
Predictors of quality of life gains among people with type 1 diabetes participating in the Dose Adjustment for Normal Eating (DAFNE) structured education programme
(Elsevier, 2012-11)Aims: To examine predictors of quality of life gains among people with type 1 diabetes following the Dose Adjustment for Normal Eating (DAFNE) self-management training programme.Methods: Clinical and questionnaire data ... -
Linguistic and Psychometric Validation of the Diabetes-Specific Quality-of-Life Scale in UK English for Adults With Type 1 Diabetes
(American Diabetes Association, 2012-12-18)OBJECTIVE-To develop a linguistically and psychometrically validated U.K. English (U.K.! Ireland) version of the Diabetes-Specific Quality-of-Life Scale (DSQOLS) for adults with type 1 diabetes.RESEARCH DESIGN AND METHODS-We ... -
Gender-specific abnormalities in the serotonin transporter system in panic disorder
(Cambridge University Press, 2013)The central serotonergic system has been implicated in the pathophysiology of panic disorder (PD) by evidence of abnormally elevated serotonin-turnover, reduced pre- and post-synaptic 5-HT(1A-)receptor sensitivity and ... -
The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy
(2013)Objective: To study 5-HT transport and 5-HT1A receptors in temporal lobe epilepsy (TLE) and depression.Methods: Thirteen patients had PET with [C-11]DASB for 5-HTT and [F-18]FCWAY for 5-HT1A receptor binding, MRI, and ...