Inhomogeneous deformation of brain tissue during tension tests

View/ Open
Date
2012Author
Destrade, Michel
Gilchrist, Michael
Metadata
Show full item recordUsage
This item's downloads: 535 (view details)
Recommended Citation
Rashid, Badar; Destrade, Michel; Gilchrist, Michael (2012) 'Inhomogeneous deformation of brain tissue during tension tests'. Computational Materials Science, 64 :295-300.
Published Version
Abstract
Mechanical characterization of brain tissue has been investigated
extensively by various research groups over the past 50 years. These properties
are particularly important for modeling Traumatic Brain Injury (TBI). In this
research, we present the design and calibration of a High Rate Tension Device
(HRTD) capable of performing tests up to a maximum strain rate of 90/s. We use
experimental and numerical methods to investigate the effects of inhomogeneous
deformation of porcine brain tissue during tension at different specimen
thicknesses (4.0 14.0 mm), by performing tension tests at a strain rate of 30/s.
One-term Ogden material parameters (μ = 4395.0 Pa, α = −2.8)
were derived by performing an inverse finite element analysis to model all
experimental data. A similar procedure was adopted to determine Young s modulus
(E = 11200 Pa) of the linear elastic regime. Based on this analysis,
brain specimens of aspect ratio (diameter/thickness) S /1.0 are
required to minimise the effects of inhomogeneous deformation during tension
tests.