Browsing School of Natural Sciences by Title
Now showing items 140-159 of 166
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Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae
(2008)Expansions of trinucleotide repeats cause at least 15 heritable human diseases. Single-stranded triplet repeat DNA in vitro forms stable hairpins in a sequence-dependent manner that correlates with expansion risk in vivo. ... -
Reproducible, high-yielding, biological caproate production from food waste using a single-phase anaerobic reactor system
(BMC (part of Springer Nature), 2018-03-11)Background: Nowadays, the vast majority of chemicals are either synthesised from fossil fuels or are extracted from agricultural commodities. However, these production approaches are not environmentally and economically ... -
Response of farmland biodiversity to the introduction of bioenergy crops: effects of local factors and surrounding landscape context
(Wiley Open Access, 2013-07-19)The recent growth in bioenergy crop cultivation, stimulated by the need to implement measures to reduce net CO2 emissions, is driving major land-use changes with consequences for biodiversity and ecosystem service provision. ... -
Restriction of human polyomavirus BK virus DNA replication in murine cells and extracts
(2009)BK virus (BKV) causes persistent and asymptomatic infections in most humans and is the etiologic agent of polyomavirus-associated nephropathy (PVAN) and other pathologies. Unfortunately, there are no animal models with ... -
A review of the Rotokawa Geothermal Field, New Zealand
(Elsevier, 2015-07-29)The Rotokawa Geothermal Field of New Zealand has seen significant development over the last 20 years and has been the study site for new and innovative geological and geothermal research. This includes the one of the first ... -
A review of the shortcomings in the testing methods used and reporting of data in the literature on antimicrobial susceptibility
(European Association of Fish Pathologists, 2020-06-02)The susceptibility test protocols used in 186 published papers that reported 203 studies of the antimicrobial susceptibility of non-cholera Vibrio spp were examined. Only a very small percentage of the studies provided ... -
RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells
(Elsevier, 2018-02-06)Receptor-interacting protein 2 (RIP2) is an essential mediator of inflammation and innate immunity, but little is known about its role outside the immune system. Recently, RIP2 has been linked to chemoresistance of triple ... -
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster
(eLife Sciences Publications, 2019-11-05)Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that ... -
Rock properties of Greywacke Basement hosting geothermal reservoirs, New Zealand: preliminary results
(Stanford University, 2014-02-24)Geothermal resources in New Zealand are known to be hosted in greywacke basement rocks. Fluid flow in these reservoirs and the wells that access them is controlled by fracture networks. As such it is of vital importance ... -
Role of alginate lyase in cell detachment of Pseudomonas aeruginosa
(American Society for Microbiology, 1994-07)The exopolysaccharide alginate of Pseudomonas aeruginosa was shown to be important in determining the degree of cell detachment from an agar surface. Nonmucoid strain 8822 gave rise to 50-fold more sloughed cells than ... -
Role of mitochondria in neuronal apoptosis
(Karger Publishers, 2000-12)Apoptosis is a controlled form of cell death that participates in the demise of neuronal cells during development, neurodegenerative disorders and exposure to neurotoxic agents. In recent years, the mitochondria have emerged ... -
Setting epidemiological cut-off values for bacteria isolated from aquatic animals: a toolbox for designing a 96-well plate for microdilution MIC assays
(European Association of Fish Pathologists, 2020-06-02)A workshop was held at the EAFP meeting in Porto to initiate discussion on the design of studies that could generate the data needed to set epidemiological cut-off values appropriate for application to antimicrobial ... -
Snake venom potency and yield are associated with prey‐evolution, predator metabolism and habitat structure
(Wiley, 2019-01-07)Snake venom is well known for its ability to incapacitate and kill prey. Yet, potency and the amount of venom available varies greatly across species, ranging from the seemingly harmless to those capable of killing vast ... -
Specificity and sensitivity evaluation of novel and existing Bacteroidales and Bifidobacteria-specific PCR assays on feces and sewage samples and their application for microbial source tracking in Ireland
(Elsevier, 2009)Three novel ruminant-specific PCR assays, an existing ruminant-specific PCR assay and five existing human-specific PCR assays, which target 16S rDNA from Bacteroidales or Bifidobacteria, were evaluated. The assays were ... -
Standard protocols for antimicrobial susceptibility testing of Vibrionaceae isolated from aquatic animals
(European Association of Fish Pathologists, 2018-07-18)A review of the relevant literature has shown that it is safe to recommend that the antimicrobial susceptibility of the species of the Vibrionaceae most commonly isolated from aquatic animals can be established using ... -
Statistical corrections of fracture sampling bias in boreholes from acoustic televiewer logs
(New Zealand Geothermal Workshop, 2012)Targeting structurally controlled permeability remains a challenge in high temperature geothermal fields, because of the difficulties in characterising faults and fractures and their behaviour within the reservoir. The ... -
Stress management at the ER: regulators of ER stress-induced apoptosis.
(Elsevier, 2012-02-17)The endoplasmic reticulum (ER) is an elaborate cellular organelle essential for cell function and survival. Conditions that interfere with ER function lead to the accumulation and aggregation of unfolded proteins which are ... -
SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation
(Wiley Open Access and Federation of European Biochemical Societies, 2022-01-24)The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase ¿-primase (Pol-prim). Since cellular ... -
SV40 T antigen interactions with ssDNA and replication protein A: a regulatory role of T antigen monomers in lagging strand DNA replication
(Oxford University Press (OUP), 2020-03-04)DNA replication is a central process in all living organisms. Polyomavirus DNA replication serves as a model system for eukaryotic DNA replication and has considerably contributed to our understanding of basic replication ... -
Systems-based approaches to unravel multi-species microbial community functioning
(Research Network of Computational and Structural Biotechnology, 2014-12-03)Some of the most transformative discoveries promising to enable the resolution of this century's grand societal challenges will most likely arise from environmental science and particularly environmental microbiology ...