Browsing School of Chemistry by Author "Cheung, David L."
Now showing items 1-20 of 32
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Adsorption and conformations of lysozyme and α-lactalbumin at a water-octane interface
Cheung, David L. (AIP Publishing, 2017-11)As proteins contain both hydrophobic and hydrophilic amino acids, they will readily adsorb onto interfaces between water and hydrophobic fluids such as oil. This adsorption normally causes changes in the protein structure, ... -
Adsorption of the natural protein surfactant Rsn-2 onto liquid interfaces
Brandani, Giovanni B.; Vance, Steven J.; Schor, Marieke; Cooper, Alan; Kennedy, Malcolm W.; Smith, Brian O.; MacPhee, Cait E.; Cheung, David L. (Royal Society of Chemistry, 2017-02-27)To stabilize foams, droplets, and films at liquid interfaces nature has evolved a range of protein biosurfactants. Compared to synthetic surfactants, these combine surface activity with biocompatibility and low solution ... -
Aggregation of nanoparticles on one and two-component bilayer membranes
Cheung, David L. (AIP Publishing, 2014)Using dissipative particle dynamics simulations the aggregation of nanoparticles on single and two-component bilayers is investigated. For a uniform bilayer the aggregation of nanoparticlesdepends strongly on the location ... -
The air-water interface stabilizes α-helical conformations of the insulin B-chain
Cheung, David L. (AIP Publishing, 2019-08-09)Adsorption of proteins onto liquid interfaces, such as the air-water interface, often leads to changes in the protein conformation. This can lead to changes in protein assembly behaviour, with aggregation and fibrillation ... -
The air-water interface stabilizes α-helical conformations of the insulin B-chain
Cheung, David L. (NUI Galway, 2019-09-16)Dataset to accompany article: Cheung, David L. (2019). The air-water interface stabilizes α-helical conformations of the insulin B-chain. The Journal of Chemical Physics, 151(6), 064706. doi: 10.1063/1.5100253 -
Atomistic study of zwitterionic peptoid antifouling brushes
Cheung, David L.; Lau, King Hang Aaron (NUI Galway, 2018-09-03)Simulation files, analysis scripts, and output data to accompany article: Cheung, David L., & Lau, King Hang Aaron. (2018). Atomistic Study of Zwitterionic Peptoid Antifouling Brushes. Langmuir. doi: 10.1021/acs.langm ... -
Atomistic study of zwitterionic peptoid antifouling brushes
Cheung, David L.; Lau, King Hang Aaron (American Chemical Society, 2018-08-24)Using molecular dynamics (MD) simulations, we study the molecular behavior and hydration properties of a set of zwitterionic peptoid brushes, grafted on a rutile surface, that has been previously reported to exhibit ... -
CO2-responsive polyacrylamide copolymer vesicles with acid-sensitive morpholine moieties and large hydrophobic RAFT end-group
Chalmers, Benjamin A.; Magee, Christopher; Cheung, David L.; Zetterlund, Per B.; Aldabbagh, Fawaz (Elsevier, 2017-10-07)Sequential Reversible Addition Fragmentation Chain Transfer (RAFT) polymerizations using 2,2′-azobis[2-(2-imidazolin-2-yl)propane]dihydrochloride (VA-044) and 2-(dodecylthiocarbonothioylthio)-2-methylpropionic acid ... -
Conformations of myoglobin-derived peptides at the air-water interface
Cheung, David L. (NUI Galway, 2016-12-12)Simulation files, analysis scripts, and output data to accompany article: Cheung, David L. (2016). Conformations of Myoglobin-Derived Peptides at the Air–Water Interface. Langmuir, 32(18), 4405-4414. doi: 10.1021/acs.la ... -
Conformations of myoglobin-derived peptides at the air-water interface
Cheung, David L. (American Chemical Society, 2016-04-14)The conformational change exhibited by proteins at liquid interfaces, such as the air-water and oil-water interfaces, has long been of interest, both for understanding protein structure outside of native environments and ... -
Design principles for the formation of ordered patterns in binary mixtures of colloidal particles on spherical droplets
Fortuna, Sara; Cheung, David L. (Elsevier, 2017-03-11)We elucidate the design principles for the formation of ordered structures formed by binary mixtures of particles on spherical surfaces, such as emulsion droplets, polymer vesicles, and col- loidal nanoparticles. Using ... -
Effect of substrate geometry on liquid-crystal-mediated nanocylinder-substrate interactions
Cheung, David L.; Allen, Michael P. (American Institute of Physics, 2008)Using classical density functional theory, the liquid crystal (LC)-mediated interaction between a cylindrical nanoparticle and a structured substrate is studied. The surface is structured by cutting a rectangular groove ... -
Effect of surface chemistry on islet amyloid polypeptide conformation
Cheung, David L. (American Institute of Physics, 2020-09-04)The formation of dense, linear arrays (fibrils) by biomolecules is the hallmark of a number of degenerative diseases, such as Alzheimer s and type-2 diabetes. Protein fibrils have also attracted interest as building blocks ... -
Effect of surface structure on peptide adsorption on soft surfaces
Cheung, David L. (Elsevier, 2020-08-28)Understanding protein adsorption onto material surfaces is a major challenge in the design of biomaterials. While this has been long studied, knowledge of how the nanoscale surface structure affects protein adsorption is ... -
Effect of the air–water interface on the conformation of amyloid beta
Samantray, Suman; Cheung, David L. (American Institute of Physics, 2020-12-17)ABSTRACT It has long been recognized that liquid interfaces, such as the air water interface (AWI), can enhance the formation of protein fibrils. This makes liquid interfaces attractive templates for fibril formation but ... -
Experimental and computational examination of anastellin (FnIII1c)-polymer interactions
Mallinson, David; Cheung, David L.; Simionesie, Dorin; Mullen, Alexander B.; Zhang, Zhenyu J.; Lamprou, Dimitrios A. (Wiley, 2016-10-24)Using a combination of experimental and computational approaches, the interaction between anastellin, a recombinant fragment of fibronectin, and representative biomaterial surfaces has been examined. Anastellin and ... -
How stable are amphiphilic dendrimers at the liquid liquid interface?
Cheung, David L.; Carbone, Paola (Royal Society of Chemistry, 2013)By means of molecular dynamics simulations the free energy of adsorption of model dendrimer characterized by monomers of different chemical affinity is predicted as a function of the number and position of the monomers. ... -
Interaction of nanoparticles with ideal liquid-liquid interfaces
Cheung, David L. (2009)Using molecular simulations the interaction between a noncharged nanoparticle and an ideal liquid-liquid interface is studied. The free energy profile as function of nanoparticle-interface separation is determined using ... -
Liquid-crystal-mediated force between a cylindrical nanoparticle and substrate
Cheung, David L. (American Physical Society, 2007-10-25)Using classical density functional theory, the structure of a molecular fluid around a cylindrical nanoparticle near a solid substrate is studied. The solvent-mediated force between the nanoparticle and the substrate is ... -
Mechanochemical tuning of the binaphthyl conformation at the air water interface
Cheung, David L. (Wiley, 2015-06-12)Gradual and reversible tuning of the torsion angle of an amphiphilic chiral binaphthyl, from −90° to −80°, was achieved by application of a mechanical force to its molecular monolayer at the air–water interface. This 2D ...