Browsing School of Chemistry by Title
Now showing items 1-20 of 218
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Additive tuning redox potential in metallacarboranes by sequencial halogen substitution
(Wiley, 2010-04-21)The first artificially made set of electron acceptors is presented that are derived from a unique platform Cs[3,3′-Co(C2B9H11)2], for which the redox potential of each differs from its predecessor by a fixed amount. The ... -
Adsorption and conformations of lysozyme and α-lactalbumin at a water-octane interface
(AIP Publishing, 2017-11)As proteins contain both hydrophobic and hydrophilic amino acids, they will readily adsorb onto interfaces between water and hydrophobic fluids such as oil. This adsorption normally causes changes in the protein structure, ... -
Adsorption of the natural protein surfactant Rsn-2 onto liquid interfaces
(Royal Society of Chemistry, 2017-02-27)To stabilize foams, droplets, and films at liquid interfaces nature has evolved a range of protein biosurfactants. Compared to synthetic surfactants, these combine surface activity with biocompatibility and low solution ... -
Aggregation of nanoparticles on one and two-component bilayer membranes
(AIP Publishing, 2014)Using dissipative particle dynamics simulations the aggregation of nanoparticles on single and two-component bilayers is investigated. For a uniform bilayer the aggregation of nanoparticlesdepends strongly on the location ... -
Allelopathic interactions between the brown algal genus lobophora (dictyotales, phaeophyceae) and scleractinian corals
(Nature Publishing Group, 2016-01-05)Allelopathy has been recently suggested as a mechanism by which macroalgae may outcompete corals in damaged reefs. Members of the brown algal genus Lobophora are commonly observed in close contact with scleractinian corals ... -
Allylic azide rearrangement in tandem with Huisgen cycloaddition for stereoselective annulation: synthesis of C-Glycosyl iminosugars
(American Chemical Society, 2015-12-09)Allylic azide rearrangement is used. in,tandem with. intramolecular azide-alkene cycloaddition to give a triazoline that when subsequently decomposed in the presence of a nucleophile gives piperidines. The tandem reaction ... -
Allylic azide rearrangement in tandem with intramolecular Huisgen cycloaddition for iminosugar and glycomimetic synthesis. Functionalized piperidine, pyrrolidine and pyrrolotriazoles from D-mannose
(Thieme Publishing, 2017-04-20)Intramolecular Huisgen azide-alkene cycloaddition reaction of 7-azido-hepta-1,5-diene-3,4-diols, prepared from methyl α-d-mannopyranoside, were carried out. Allylic azide rearrangement to secondary azides occurred ... -
Alternating bimetallic Na/Mn covalent and ionic chains
(RSC, 2010-07-30)The first coordination polymers constructed using the 2,2'-biphenol ligand are described along with their ionic supramolecular counterparts. -
Analysis of hydrocarbon bearing fluid inclusions HCFI) using time-resolved fluorescence spectroscopy
(Society of Photo-optical Instrumentation Engineers, 2005)Hydrocarbon-bearing fluid inclusions (HCFI) are microscopic cavities within rocks that are filled with petroleum oil, the composition of which may not have changed since the trapping event. Thus, the composition of that ... -
Anisotropy resolved multidimensional emission spectroscopy (ARMES): A new tool for protein analysis
(Elsevier, 2015-07-30)Structural analysis of proteins using the emission of intrinsic fluorophores is complicated by spectral overlap. Anisotropy resolved multidimensional emission spectroscopy (ARMES) overcame the overlap problem by the use ... -
Antitumor platinum(IV) derivatives of carboplatin and the histone deacetylase inhibitor 4-phenylbutyric acid
(Elsevier, 2017-09-10)Five new platinum(IV) derivatives of carboplatin each incorporating the histone deacetylase inhibitor 4-phenylbutyrate in axial position were synthesized and characterized by 1H and 195Pt NMR spectroscopy, electrospray ... -
Application of vibrational spectroscopy to study solid-state transformations of pharmaceuticals
(2016-09-01)Understanding the properties, stability and transformations of the solid-state forms of an active pharmaceutical ingredient (API) in the development pipeline is of crucial importance for process-development, formulation ... -
Applications of raman spectroscopy in biopharmaceutical manufacturing: A short review
(Sage Publications, 2017-05-23)The production of active pharmaceutical ingredients (APIs) is currently undergoing its biggest transformation in a century. The changes are based on the rapid and dramatic introduction of protein- and macromolecule-based ... -
Assessing the predictions of a NOx kinetic mechanism on recent hydrogen and syngas experimental data
(Elsevier, 2017-05-02)A detailed chemical kinetic mechanism has been developed to describe the pyrolysis and oxidation of the hydrogen/NOx and syngas/NOx systems. The thermodynamic data of nitrogenous compounds have been updated based on the ... -
Autoignition of ethanol in a rapid compression machine
(Elsevier, 2013-12-09)Ethanol is a renewable source of energy and significant attention has been directed to the development of a validated chemical kinetic mechanism for this fuel. The experimental data for the autoignition of ethanol in the ... -
Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins
(Royal Society of Chemistry, 2015-02-17)Emerging insights into the functional spectrum of tissue lectins leads to identification of new targets for the custom-made design of potent inhibitors, providing a challenge for synthetic chemistry. The affinity and ... -
Bi- to tetravalent glycoclusters: synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity.
(Royal Society of Chemistry, 2012-06-29)The emerging functional versatility of cellular glycans makes research on the design of synthetic inhibitors a timely topic. In detail, the combination of ligand (or headgroup or contact site) structure with spatial ... -
Bodipy-ruthenium(II) tris-bipyridyl dyads for homogeneous photochemical oxidations
(Elsevier, 2014-10-28)Two Bodipy-ruthenium(II) tris-bipyridyl dyads were synthesized for use as sensitizers in photochemical oxidation reactions of organic substrates. The synthetic strategy involved the use of a simple ‘click’ CuAAC reaction ... -
Cell cycle-dependent mobility of Cdc45 in living cells determined by fluorescence correlation spectroscopy.
(Public Library of Science, 2012)Eukaryotic DNA replication is a dynamic process requiring the co-operation of specific replication proteins. We measured the mobility of eGFP-Cdc45 by Fluorescence Correlation Spectroscopy (FCS) in vivo in asynchronous ... -
Chain transfer to solvent in the radical polymerization of structurally diverse acrylamide monomers using straight-chain and branched alcohols as solvents
(Royal Society of Chemistry, 2014-01-02)Chain transfer to solvent in conventional radical polymerizations of N-tert-butylacrylamide (TBAM) and N-(2-morpholin-4-ylethyl) acrylamide (MEA) in a range of alcohol solvents is investigated. Mayo analysis of polymerization ...