Browsing School of Chemistry by Author "Fresch, B."
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A Cu(II) complex targeting the translocator protein: in vitro and in vivo antitumor potential and mechanistic insights
Montagner, D.; Fresch, B.; Browne, K.; Gandin, V.; Erxleben, Andrea (Royal Society of Chemistry, 2016-12-01)A new Cu-based anticancer metallodrug which targets the translocator protein is reported. [CuBr2(TZ6)] elicits a remarkable in vitro cytotoxicity in sensitive and multidrug resistant cell lines and induces a 98% reduction ...