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Bovine kappa-casein gene promoter haplotypes with potential implications for milk protein expression
(Elsevier ScienceDirect, 2007-05-25)
Genetic analysis of the kappa-casein gene (CSN3) promoter regions of 42 cattle representing 9 different breeds revealed that 2 distinct haplotypes (A and B) exist at this locus, differing from each other by single base ...
Scale-up of bileaflet mechanical heart valve for enhanced resolution of the unsteady flow field
(University of Limerick, 2009-01-30)
Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats
(Blackwell, 2008-10)
The endogenous cannabinoid system plays an important role in regulating the immune system. Modulation of endogenous cannabinoids represents an attractive alternative for the treatment of inflammatory disorders. This study ...
Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury
(BioMed Central Ltd., 2008-07-08)
Background:
Hypertonic saline (HTS) reduces the severity of lung injury in ischemia-reperfusion, endotoxin-induced and ventilation-induced lung injury. However, the potential for HTS to modulate the resolution of lung ...
Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin
(BioMed Central, 2009-01-08)
Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are not ...
Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models
(2004-03-05)
This work explores a new approach to gene-prediction, based on the Self-Organizing Map, which has the ability to automatically identify multiple gene models within a genome. The current implementation, named RescueNet, ...
Global gene expression analysis of the effects of Vinblastine on endothelial cells, when eluted from a thermo-responsive polymer
(Wiley Online Library, 2006-06-30)
In-stent restenosis remains a significant problem associated with bare metal stents. This drawback has prompted research into improving stent design and the development of novel coatings, including drug-eluting stents. A ...
Human chorionic gonadotrophin relaxation of human pregnant myometrium and activation of the BKCa channel
(2003)
The uterorelaxant effect of human chorionic gonadotropin (hCG) is regarded as an important mediator in maintenance of uterine quiescence during pregnancy with clinical potential for tocolysis, the mechanisms of which are ...
Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction
(Society for Reproduction and Fertility, 2006-07-01)
Pre eclampsia represents a state of increased or prolonged vasoconstriction, partially linked to the potent vasocontractile effect of isoprostanes. The process of Rho A-mediated calcium sensitisation is inherent to a state ...