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Occupational therapy interventions for multiple sclerosis: A scoping review
(Taylor & Francis (Routledge), 2020-07-09)
We reviewed the evidence regarding the effectiveness of occupational therapy interventions in improving outcomes for adults with multiple sclerosis.
Method
We completed a scoping review of literature in the area of ...
Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots
(Public Library of Science, 2019-12-05)
Our aim was to assess the utility of a novel machine learning software (Orbit Image Analysis) in the histological quantification of acute ischemic stroke (AIS) clots. We analyzed 50 AIS blood clots retrieved using mechanical ...
Estimating the health-care costs of wound care in Ireland
(Mark Allen Healthcare, 2019-06-05)
Objective: To estimate the cost of wound care to the Irish health-care system.Methods: A bottom-up, prevalence-based analysis was undertaken using a decision analytic model to estimate costs. Health-care resource activity ...
The profile of patients with venous leg ulcers: A systematic review and global perspective
(Elsevier, 2020-08-13)
A holistic profile that includes demographic, medical history and wound characteristics of individuals with venous leg ulceration is lacking. Lack of such a profile negatively impacts the ability to develop interventions ...
A qualitative investigation of reasoning behind decisions to decline participation in a research intervention: A study-within-a-trial
(SAGE Publications, 2021-08-06)
The current study-within-a-trial explored individuals’ decisions to decline participation in research trialling a chronic illness-focused therapy (i.e. multiple sclerosis). Four themes were identified from seven semi-structured ...
Exploring the impact of ineligibility on individuals expressing interest in a trial aimed at improving daily functioning regarding perceptions of self, research and likelihood of future participation
(BMC, 2021-11-27)
Background
Eligibility guidelines in research trials are necessary to minimise confounds and reduce bias in the interpretation of potential treatment effects. There is limited extant research investigating how being deemed ...
Does prior administration of rtPA influence acute ischemic stroke clot composition? Findings from the analysis of clots retrieved with mechanical thrombectomy from the RESTORE registry
(Springer, 2021-08-20)
Background and purpose
There is still much debate whether bridging-therapy [intravenous thrombolysis (IVT) prior to mechanical thrombectomy (MT)] might be beneficial compared to MT alone. We investigated the effect of IVT ...
The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does not influence revascularization outcome
(Springer, 2020-09-16)
Both intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are evidence-based treatments for acute ischemic stroke (AIS) in selected cases. Recanalization may occur following IVT without the necessity of further ...
Potential biomarkers of acute ischemic stroke etiology revealed by mass spectrometry based proteomic characterization of formalin-fixed paraffin-embedded blood clots
(Frontiers Media, 2022-04-19)
Background and Aims: Besides the crucial role in the treatment of acute ischemic stroke (AIS), mechanical thrombectomy represents a unique opportunity for researchers to study the retrieved clots, with the possibility of ...
A standardized aspiration-first approach for thrombectomy to increase speed and improve recanalization rates
(American Society of Neuroradiology, 2019-08-14)
BACKGROUND AND PURPOSE: Direct aspiration is a recognized technique for revascularization in large-vessel ischemic strokes. There is ongoing debate regarding its efficacy compared with stent retrievers. Every delay in ...