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FAAH inhibition attenuates TLR3-mediated hyperthermia, nociceptive- and anxiety-like behaviour in female rats
(Elsevier, 2018-06-25)
Aberrant activation of toll-like receptor (TLR)s results in persistent and prolonged neuroinflammation and has been implicated in the pathogenesis and exacerbation of psychiatric and neurodegenerative disorders. TLR3 ...
Patterns of occupational engagement among community-dwelling older adults in Singapore: An exploratory mixed method study
(SAGE Publications, 2021-05-04)
Introduction
The aim of this study is to understand the patterns of occupations among community-dwelling older adults in Singapore. The objectives are to describe their occupational engagement using the Activity Card Sort ...
Subconjunctival administration of low-dose murine allogeneic mesenchymal stromal cells promotes corneal allograft survival in mice
(BMC, 2021-04-06)
Systemic administration of mesenchymal stromal cells (MSCs) has been efficacious in many inflammatory disease settings; however, little data are available on the potential immunomodulatory effects following local MSC ...
Salt and cardiovascular disease: insufficient evidence to recommend low sodium intake
(Oxford University Press, 2020-10-04)
Several blood pressure guidelines recommend low sodium intake (<2.3 g/day, 100 mmol, 5.8 g/day of salt) for the entire population, on the premise that reductions in sodium intake, irrespective of the levels, will lower ...
Examining the utility of the DESCARTE model for case study research
(Slack, 2021-03-01)
The DESCARTE model aims to guide health care researchers on the design, conduct, and reporting of case studies. The current article critically appraises the utility of the model and provides an example of its application ...
“Stuck between a rock and a hard place”: How mental health nurses’ experience psychosocial interventions in Irish mental health care settings
(Wiley, 2020-10-19)
4.1 Description
The paper will report on the interview data of trained MHNs experiences of using PSI within the Irish context. This observational data will be reported elsewhere (Smyth et al. 2020 under review).
4.2 ...
Research interrupted: The impact of the COVID-19 pandemic on multiple sclerosis research in the field of rehabilitation and quality of life
(SAGE Publications, 2021-08-26)
Background
The COVID-19 pandemic has likely had a negative impact on rehabilitation and quality of life (QoL) research in multiple sclerosis (MS).
Method
We explored perceived barriers to research among 87 researchers, ...
The perceptions of people with dementia and key stakeholders regarding the use and impact of the social robot MARIO
(MDPI, 2020-11-20)
People with dementia often experience loneliness and social isolation. This can result in increased cognitive decline which, in turn, has a negative impact on quality of life. This paper explores the use of the social ...
The discursive construction of HIV stigma in Irish print media
(SAGE Publications, 2021-08-23)
As interlocutors in national level discourse with the power to influence public opinion and inform policy, the news media are an important data source in understanding the
constitutive roles played by culture and discourse ...
Prevalence of burnout among Irish general practitioners: a cross-sectional study
(Springer, 2016-01-23)
Burnout constitutes a significant problem among physicians which impacts negatively upon both the doctor and their patients. Previous research has indicated that burnout is prevalent among primary care physicians in other ...