NUI Galway Theses (PhD Theses)
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On the application of analytical techniques to mobile network CDRs for the characterisation and modelling of subscriber behaviour
(NUI Galway, 2018-06-13)This thesis describes work completed on the characterisation and modelling of the behaviour of subscribers in mobile phone networks implementing dynamic pricing by means of Call Detail Records (CDR) datasets analysis. The ... -
Characterisation of triple negative breast carcinoma and identification of the value of immunohistochemical markers and stromal tumour infiltrating lymphocytes
(NUI Galway, 2017-10)Breast cancer is a complex disease that encompasses multiple molecular subtypes that have different clinical behavior. The behavior can be influenced by both the characteristics of the cancer cells as well as the surrounding ... -
Contributions to the measurement of depth in consumer imaging
(NUI Galway, 2018-06-12)This thesis aims to examine and investigate methods that could potentially utilize images captured by consumer cameras such as smartphones to estimate depth and generate a 3D structure. After more than a century of ... -
ATR mediated regulation of the abscission checkpoint
(NUI Galway, 2018-05-30)Unperturbed mitotic cell division is essential for survival. For cells to complete mitosis, genetic material must be distributed equally between the new cells before the final abscission. Failure to complete chromosome ... -
From Gaelic lordships to English counties: the Tudor transition in Leix and Offaly, c.1547-1603
(NUI Galway, 2018-05-29)This study evaluates whether or not successive Tudor regimes effectively transformed the Gaelic lordships of Leix and Offaly into English counties and as a direct consequence, administered these territories through the ... -
Pro-inflammatory cytokine licensing as a strategy to enhance the efficacy of syngeneic mesenchymal stem cells for corneal transplantation
(NUI Galway, 2018-05-11)It has previously been demonstrated by our lab that allogeneic MSCs prolong corneal allograft survival however syngeneic MSCs fail to do so. The aim of this study was to investigate if pre-treating syngeneic MSCs with ... -
Aspects of modeling and application of survival-type data
(NUI Galway, 2018-02)Survival analysis is collection of methods for analyzing data where the outcome of interest is the time to an event and some of the observations are censored. Survival data can arise naturally from studies on, machines' ... -
An investigation of reading abilities and the impact of programmed instruction on reading outcomes in children with autism specrtum disorder
(NUI Galway, 2018-05-11)This thesis investigates reading abilities and programmed instruction, i.e., instruction that is scripted and sequenced, with explicit learning goals, based on the principles of Applied Behaviour Analysis, in children with ... -
Estimating the value of the benefits of the Marine Strategy Framework Directive
(NUI Galway, 2018-05-11)The European Union introduced the Marine Strategy Framework Directive (MSFD) to ensure that Europe's seas are healthy, clean and productive. To meet these goals, decisions will have to be made and cost and benefits weighed ... -
Genomic integrity of human norovirus and F-RNA bacteriophage as detected by RT-qPCR and its relationship to infectivity before and after UV-treatment
(NUI Galway, 2018-05-10)A long-range RT (loRT) qPCR assay described to estimate levels of infectious virus was identified in the literature and applied to human norovirus (HuNoV) genogroups I and II (GI and GII), and the surrogate virus F-RNA ... -
An examination of the antecedents and outcomes of career capital development during international assignments: A study of repatriates
(NUI Galway, 2017-11-09)This study focuses on individual development, characterised as career capital, in the context of traditional international assignments (IAs). Individual development is a key concern for multinational enterprises. Similarly, ... -
Transcriptome analysis in Hydractinia echinata reveals species-specific and phylum-wide gene loss
(NUI Galway, 2018-05-04)The advances and subsequent widespread use of next-generation sequencing, in particular transcriptomics, has allowed biologists to approach questions and study many more powerful and previously underappreciated model animals ... -
In their own words. Factors impacting on the higher education (HE) experiences of black and minority ethnic (BME) students in Ireland
(NUI Galway, 2017-09-30)This study examines the experiences of black and minority ethnic (BME) groups in Irish higher education (HE). While the HE and wider experiences of this group are the focus of research and policy internationally, this study ... -
Bone marrow stromal cell transplantation ameliorates cytopenias caused by depletion of FAP-α expressing cells
(NUI Galway, 2018-05-03)Mesenchymal stromal cell (MSC) therapies are being successfully developed for immune-mediated inflammatory diseases as phase 3 clinical trials have demonstrated. However, the en-dogenous roles of stromal cells (SSCs) are ... -
Trends in the incidence and outcomes of end stage kidney disease from specific causes and the ability of measures of kidney function to predict mortality in community dwelling individuals
(NUI Galway, 2018-03-09)Summary of Contents There are two broad themes in this research thesis. The first is an exploration of the ability of measures of kidney function and urinary protein excretion to predict death based on non-parametric ... -
Genesis of the Moly Brook molybdenum-copper deposit, Newfoundland, Canada: Geological and geochemical constraints on fluid evolution, links with adjacent tungsten mineralization, and the role of Late Devonian granitic intrusions
(NUI Galway, 2017-08-25)An integrated geological, structural and geochemical study of the Moly Brook Mo-Cu deposit, southern Newfoundland (Canada), is presented. The role of subordinate leucogranite as progenitor to the mineralizing components ... -
Examining the legitimation strategies of sustainability-oriented entrepreneurs
(NUI Galway, 2018-03-29)The idea that business plays a crucial role in the sustainable development of our world has grown within the corporate sustainability literature and in global sustainability discourse generally. There is also a growing ... -
Amorphous pharmaceuticals and composites
(NUI Galway, 2018-04-27)An attractive, yet challenging approach to overcome poor water solubility is to convert a crystalline Active Pharmaceutical Ingredient (API) into its more soluble amorphous form.1-3 Nevertheless, the use of amorphous drug ... -
Online community success - A study of success criteria and user behaviour in online communities
(NUI Galway, 2017-10-27)In a world where online users form communities for various purposes and around many different topics of interest, it has become of social and economic importance for owners, providers and managers of online communities to ... -
Confocal microwave imaging and artifact removal algorithms for the early detection of breast cancer
(NUI Galway, 2018-03-29)Microwave imaging is an emerging imaging modality for the early detection of breast cancer. Early-time artifact removal and imaging algorithm are the two most important signal processing components of any Confocal Microwave ...