NUI Galway Theses (PhD Theses)
Browse by
Recent Submissions
-
Metastatic breast cancer: Patterns of metastasis and novel biomarkers
(NUI Galway, 2018-05-25)Breast cancer is a heterogeneous disease and is the leading cause of cancer-related deaths among women, with metastatic disease the principle cause of mortality. In recent years great advances have been made in stratifying ... -
Paediatric rotavirus gastroenteritis - regional prevalent serotypes, correlation with disease severity, nosocomial acquisition, viral co-infection and the impact of rotavirus vaccine in one region of Ireland
(NUI Galway, 2019-09-13)Background: Rotavirus is the primary cause of gastroenteritis in children worldwide and a leading cause of gastroenteritis in children younger than three years, with a significant burden both globally and in Ireland. ... -
Silent noise: A textual study of John McGahern's The Dark and a novel: Copybook
(NUI Galway, 2019-09-13)The following submission represents the work of four years as a PhD Practice and Research student at NUIG in the department of English. The General Introduction describes the process from conception to application and ... -
Novel strategies for exploitation of milk glycoproteins for food ingredient applications
(NUI Galway, 2019-08-02)This thesis sets out to explore the potential bioactivities associated with the bovine milk proteome with a view to improving our understanding of the roles bovine milk proteins may play in human health promotion. The ... -
Examining the role of a novel stromal cell protein CD362/Syndecan-2 in the breast tumour microenvironment.
(NUI Galway, 2019-09-04)Tumour-associated stromal cells play a key role in initiating and sustaining tumour growth, metastasis, immune control and chemo-resistance. Thus, identifying stromal proteins that contribute to carcinogenesis may open new ... -
Investigation of biological factors that may contribute to bioactivity in Haliclona (Porifera, Haplosclerida)
(NUI Galway, 2019-09-06)Sponges (phylum Porifera) are considered the most prolific source of bioactive compounds of marine origin. These molecules have varied chemical nature and have been shown to possess several properties, e.g. antibacterial, ... -
The influence of silvicultural practices on mechanical properties of softwood timber
(NUI Galway, 2019-06)The increase in the use of structural timber in construction over recent years has been one of the main drivers behind the renewed interest in optimizing forest management for timber quality. Past research and forest ... -
The decoration of the litterae notabiliores in the Cathach of Columcille
(NUI Galway, 2019-09-02)The aim of this study is to examine the litterae notabiliores of what is known as the Cathach of Colum Cille (RIA MS. 12 R 33), the manuscript of a fragment of a psalter said to have been written in the late sixth century ... -
Medieval settlement enclosures and resource management of living trees in Gaelic Ireland
(NUI Galway, 2019-08-23)The aim of this thesis is to problematise and investigate relationships between living trees and earthen settlement enclosures, mainly termed ráth and commonly used by Gaelic society in medieval Ireland (c. 8th – 17th ... -
Zhu reduction theory for vertex operator algebras on Riemann surfaces
(NUI Galway, 2019-08-21)In this thesis we first develop a recursive relation for $n$-point functions for Vertex Operator Super Algebras (VOSAs) on a genus two Riemann surface constructed by sewing two tori. This relation is used to develop formal ... -
Professional women’s entrepreneurship in Amman City, Jordan: Drivers and impacts
(NUI Galway, 2019-08-20)Women entrepreneurs took more than 30 years to be identified as an individual group. Yet, early work on women’s entrepreneurship can be branded as mostly descriptive, examining. Women’s entrepreneurship has been used as ... -
Development of drugs targeting the human tRNA ligase RtcB in breast cancer
(NUI Galway, 2019-02-15)The RNA ligase RtcB has been shown to regulate RNA function by direct exon ligation of spliced XBP1 messenger RNA cleaved by the endoplasmic reticulum (ER) stress sensor IRE1α. Ligation by RtcB leads to the expression of ... -
The life-cycle of methanogenic granular biofilms
(NUI Galway, 2019-08-19)Anaerobic granules, sometimes referred to as methanogenic granules, underpin the sustainable treatment of wastewater in high-rate anaerobic bioreactors. They are spontaneously-forming self-immobilised biofilm aggregates ... -
The multi-spectral signal properties of multiple reference optical coherence tomography
(NUI Galway, 2019-07-05)Efforts to reduce the size and costs of optical coherence tomography systems (OCT) for consumer applications, in general, focus on Fourier-domain OCT, due to its potential to be integrated on an optical chip, implementing ... -
The application of machine learning to optimise live migration in cloud data centres
(NUI Galway, 2019-08-06)Cloud computing providers utilise large-scale data centres to provide computing resource to users’ worldwide. However, an ongoing challenge facing cloud providers is to ensure that the required resource is available to ... -
A new business model for cell-based therapeutics
(NUI Galway, 2011-06)Cell-based therapeutics have attracted large amounts of investment as they may offer effective treatments for a wide variety of health problems. In spite of extensive research relatively few examples of successful ... -
Nitrogen removal using partial nitritation-anammox process
(NUI Galway, 2019-07-26)The partial nitritation-anammox (PN-A) process is a promising biological nitrogen-removal process. Compared with the conventional autotrophic nitrification-heterotrophic denitrification process, it requires no organic ... -
Application of electrodialysis into nutrient recovery and antibiotics removal for pig manure management
(NUI Galway, 2019-07-25)Animal manure should be regarded as a resource rather than a waste as it contains abundant nutrients (nitrogen and phosphorus) available for plants. Land spreading of animal manure is a common practice while it has to be ... -
The influence of prior knowledge and distributional justice messaging on recipient cognition
(NUI Galway, 2019-06-18)This thesis examines how recipient cognition is influenced by prior knowledge when presented with a distributional justice message. It is hypothesised the cognitive response of high prior knowledge recipients to the advocacy ... -
Between authorities: Exercises and experiments in literary appreciation
(NUI Galway, 2019-07-16)Literary criticism, of the type that follows in this project, is a series of experiments with and about the matter of authority: about how much authority a critic should want to have or be willing to give up, and how much ...