NUI Galway Theses (PhD Theses)
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Macro- and micro-scale modelling of material inhomogeneity for the premature failure of welded 9Cr steels in power plants
(NUI Galway, 2019-02-15)Chromium-molybdenum steel pipe (9Cr-1Mo steel) is an important high temperature construction material for welded steam piping networks in gas-fired power plants. A major global problem of such materials is the premature ... -
Mechanistic insights into novel cellular therapy strategies for the treatment of corneal allograft rejection
(NUI Galway, 2019-02-14)It has previously been demonstrated by our lab that tolerogenic dendritic cells (tDCs) prolong corneal allograft survival. This study revealed that tDCs had significantly higher levels of sialic acid on the cell surface ... -
A transportable distributional semantics architecture
(NUI Galway, 2019-02-13)Distributional semantics is built upon the assumption that the context surrounding a given word in text provides important information about its meaning (Distributional hypothesis). A rephrasing of the distributional ... -
Provoking performance: challenging the people, the state and the patriarchy in 1980s Irish Theatre
(NUI Galway, 2018-08-28)Summary of Contents: Provoking Performance: Challenging the People, the State and the Patriarchy in 1980s Irish Theatre This thesis offers new perspectives and knowledge to the discipline of Irish theatre studies and ... -
Investigating the temporal and phase relations of oscillatory mechanisms involved in auditory binding
(NUI Galway, 2019-02-11)Abstract Introduction: Auditory binding refers to the integration of the components of a sound to form a wholistic percept. The present research explores similarities within visual and auditory binding mechanisms by testing ... -
Shakespeare, gender, and contemporary Ireland: performing and recreating national identities
(NUI Galway, 2019-02-11)This dissertation explores the performance of Shakespeare by Irish theatre practitioners in Ireland and England at a time of significant biopolitical, social, and legislative change (2014-2018), and as such, approaches ... -
Anisotropy resolved multidimensional emission spectroscopy (ARMES) for the analysis and resolution of insulin oligomer emission
(NUI Galway, 2018-11-14)Protein aggregation is one of the biggest challenges affecting the manufacture and safe use of biopharmaceuticals. Despite efforts made to enhance protein stability [1], aggregation still remains a critical factor in ... -
How adults tell: messages for society and policy makers regarding disclosure of childhood sexual abuse
(NUI Galway, 2019-02-08)The social work profession in Ireland plays a significant role in the assessment of child sexual abuse referrals. Somewhat unique in an international context, this role encompasses assessment of disclosures by current ... -
Immunomodulation in mesenchymal stem cell therapy for osteoarthritis: mechanistic insights on the role of cell death and engraftment
(NUI Galway, 2018-11-02)Osteoarthritis (OA) is a degenerative pathology of the articular cartilage causing chronic pain and disability in millions of individuals. In OA synovia, resident macrophages and infiltrated lymphocytes contribute to the ... -
Applications of image processing for performance assessment of wastewater treatment plants
(NUI Galway, 2018-09-13)This thesis is concerned with the development of methodologies for automatically assessing fluid properties in wastewater treatment plants, and to monitor plant performance and efficiency. Reliable performance metrics are ... -
Coming 'Home': place, belonging and second-generation return migration from England to Ireland
(NUI Galway, 2018-09-28)This thesis contributes to the growing academic interest in the second-generation of migrants and the connections they maintain with their parental places of origin. It focuses on the children of the Irish emigrants to ... -
Study of silyl protecting groups in anomerisation reactions: Total synthesis of a glycolipid from Plakortis simplex and its mimetics
(NUI Galway, 2019-02-04)This thesis deals with anomerisation, which is, in other words, epimerisation at the anomeric centre, usually interpreted as being from the equatorial to the axial anomer. An objective was to enhance the knowledge of this ... -
Optimised energy management for energy harvesting powered wireless sensors
(NUI Galway, 2019-01-30)Energy harvesting provides a promising opportunity as the power source for wireless sensors for the Internet of Things (IoT) related applications (e.g. smart buildings, autonomous cars). However there are issues encountered ... -
An experimental and computational investigation of the high temperature behaviour of MarBN steel with application to effects of manufacturing
(NUI Galway, 2018-10-30)The key step for next generation power plants is the development of advanced materials capable of achieving high flexibility and efficiency at increased steam temperatures and pressures. Such operating conditions will cause ... -
Home Rule from a transnational perspective: The Irish Parliamentary Party and the United Irish League of America, 1901-1918
(NUI Galway, 2019-02-04)When John Redmond was elected chairman of the reunited Irish Parliamentary Party (IPP) in 1900, he quickly identified a pressing need to re-engage Irish America. Ireland’s largest diaspora had grown weary of constitutional ... -
Resistance and mobilization of power: the case of Irish senior citizens
(NUI Galway, 2019-01-31)In October 2008, the Irish pensioners engaged in nation-wide public campaign of dissent in response to the government decision to abolish the universal access to medical card for the over-70s, which culminated in the largest ... -
Stem cell modelling for the role of NRXN1 deletion in Autism Spectrum Disorder
(NUI Galway, 2018-12-21)Autism spectrum disorder (ASD), a multi-factorial disease, often has co-morbidity with epilepsy, which is associated with excessive neuronal firing. The pre-synaptic protein Neurexin1 (NRXN1) signals bi-directionally through ... -
Development of a high time resolution optical polarimeter for astronomy
(NUI Galway, 2018-12-17)This work started in September, 2014 and initially started as an investigation of the characterisation issues associated with using Electron Multiplying Charge- Coupled Devices (EMCCDs) in a two beam polarimeter. It was ... -
Macromolecular crowding for chondrogenic phenotype maintenance and stem cell differentiation
(NUI Galway, 2019-01-31)Chondrocyte-based tissue engineering therapies require in vitro cell expansion, which is associated with loss of phenotype, decrease in synthesis of collagen type II and increase in synthesis of collagen type I. Another ... -
Carbohydrates in the synthesis of macrocycles and glycoclusters
(NUI Galway, 2019-01-28)This thesis deals with efforts to generate new bioactive organic compounds. The main focus has been on the use of carbohydrate building blocks for synthesis of both macrocyclic compounds and glycoclusters for biological ...