Introduction: ARDS is a syndrome of acute respiratory failure that presents with progressive arterial hypoxemia, dyspnea, and a marked increase in the work of breathing. Mechanical ventilation is necessary to support life ...

Glycogen Synthase Kinase 3 (GSK3) is involved in a myriad of signalling pathways and has recently received considerable interest due to its conflicting roles tumourigenesis. Though it has classically been regarded as a ...

Bipolar Disorder (BD) is a major psychotic illness characterized by cyclic mood dysregulation. The dysconnectivity hypothesis suggests that psychotic illnesses arise not from regionally specific focal pathophysiology, but ...

Background Stroke is the most common cause of disability in the western World. Approximately 176,000 new individuals in the United Kingdom and Ireland are diagnosed with stroke annually with up to one third experiencing ...

Breast cancer is a heterogeneous group of diseases survival from which depends on stage at diagnosis. The development of blood-based biomarkers which may facilitate earlier detection and possibly subtype delineation remains ...

Introduction: Involuntary admission is often a traumatic experience for patients and it is associated with negative attitudes which can persist after the episode of illness has abated. Aims: The aims of the study were ...

Diabetic ulcer healing is a major problem in health care. Impaired circulation has long been associated with diabetes resulting in an increased risk of foot ulceration and making an increase in blood flow an excellent ...

The ability to experience pain is essential for survival, and to prevent potential tissue damage upon exposure to noxious stimuli. The periaqueductal grey - rostral ventromedial medulla – dorsal horn of the spinal cord ...

Breast cancer is the most frequently diagnosed female malignancy worldwide, causing the majority of cancer-related deaths amongst women. While the management of this disease has transformed dramatically in recent years, ...

A well-functioning Arteriovenous Fistula (AVF) has been shown to be the best modality for access in patients with end-stage kidney disease going for dialysis. Maturation of AVF is complex and depends on various biomechanical ...