Browsing School of Chemistry by Title
Now showing items 256-275 of 360
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Performance Monitoring of a Mammalian Cell Based Bioprocess using Raman spectroscopy.
(2013)Being able to predict the final product yield at all stages in long-running, industrial, mammalian cell culture processes is vital for both operational efficiency, process consistency, and the implementation of Quality by ... -
Phosphate diester cleavage, DNA interaction and cytotoxic Activity of a bimetallic bis(1,4,7-triazacyclononane) zinc complex
(Wiley, 2014-06-24)The dinuclear zinc complex [Zn-2{bcmp(-H)}(mu-Cl)](ClO4)(2)center dot H2O {bcmp = 2,6-bis(1,4,7-triazacyclonon-1-ylmethyl)-4-methylphenol} has been synthesized and structurally characterized. The DNA binding affinity was ... -
A phosphate-targeted dinuclear Cu(II) complex combining major groove binding and oxidative DNA cleavage
(Oxford University Press, 2018-09-17)Free radical generation is an inevitable consequence of aerobic existence and is implicated in a wide variety of pathological conditions including cancer, cardiovascular disease, ageing and neurodegenerative disorder. Free ... -
Planar [Ni-7] discs as double-bowl, pseudo metallacalix[6]arene host cavities
(RSC, 2010-09-19)We report three heptanuclear[Ni-7] complexes with planar disc-like cores, akin to double-bowl metallocalix[6]arenes, which form molecular H-bonded host cavities. -
Prediction of Cell Culture Media Performance Using Fluorescence Spectroscopy
(2010)Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ... -
Prediction of Cell Culture Media performance using Fluorescence Spectroscopy
(ACS Publications, 2010)Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ... -
Prediction of cell culture media performance using fluorescence spectroscopy.
(American Chemical Society, 2010)Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ... -
Prediction of pK(a) values of nido-carboranes by density functional theory methods
(American Chemical Society, 2006-08-25)A great parallel exists between metal complexes of cyclopentadienyl and arene ligands on one side and metal complexes of the nido derivatives of the icosahedral o-carborane clusters. With few exceptions, the metal complexation ... -
Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes
(Cell Press, 2021-01-22)The small 3-O-sulfated galactose head group of sulfatides, an abundant glycosphingolipid class, poses the (sphinx-like) riddle on involvement of glycan bridging by tissue lectins (sugar code). First, synthesis of head group ... -
Probing the antagonistic effect of toluene as a component in surrogate fuel models at low temperatures and high pressures. A case study of toluene/dimethyl ether mixtures
(Elsevier, 2016-07-12)There is a dearth of experimental data which examine the fundamental low-temperature ignition (T < 900 K) behavior of toluene resulting in a lack of data for the construction, validation, and interpretation of chemical ... -
Probing the low-temperature chemistry of ethanol via the addition of dimethyl ether
(Elsevier, 2017-11-28)Considering the importance of ethanol (EtOH) as an engine fuel and a key component of surrogate fuels, the further understanding of its auto-ignition and oxidation characteristics at engine-relevant conditions (high pressures ... -
Progressive Decoration of a Pentanuclear Cu(II) 12-Metallocrown-4 Towards Targeted 1- and 2-D Extended Networks
(RSC, 2013-07-05)The synthesis, structures and magnetic characterisation of a family of discrete planar pentanuclear Cu(II) 12-MC-4 metallacrowns of formulae [Cu5(L1)4(MeOH)4](ClO4)2 (1), [Cu5(L1)4(py)2](ClO4)2·py (2), [Cu5(L1)4(py)6](ClO4)2 ... -
The pyrolysis of 2-methylfuran: a quantum chemical, statistical rate theory and kinetic modelling study
(Royal Society of Chemistry, 2014-01-27)Due to the rapidly growing interest in the use of biomass derived furanic compounds as potential platform chemicals and fossil fuel replacements, there is a simultaneous need to understand the pyrolysis and combustion ... -
Pyrolysis of n-pentane, n-hexane and n-heptane in a single pulse shock tube
(Elsevier, 2017-08-16)The pyrolysis of n-pentane, n-hexane and n-heptane have been studied behind reflected shock waves at pressures of 1.0-2.5 atm and at temperatures of 1000-1500 K. A single-pulse shock tube (SPST) was used to measure reactant, ... -
A pyrolysis study of allylic hydrocarbon fuels
(Wiley, 2020-08-17)The pyrolysis of selected C3 C5 allylic hydrocarbons has been studied using a single-pulse shock tube. A new single-pulse shock tube has been designed and constructed by recommissioning an existing conventional shock ... -
Quantitative analysis of cocaine in solid mixtures using Raman spectroscopy and chemometric methods
(Wiley, 2000)Near-infrared (785 mn) excitation was used to obtain Raman spectra from a series of 33 solid mixtures containing cocaine, caffeine and glucose (9.8-80.6% by weight cocaine), which were then analysed using chemometric ... -
Quantitative analysis of cocaine in solid mixtures using Raman spectroscopy and chemometric methods
(Wiley, 2000-04-27)Near-infrared (785 mn) excitation was used to obtain Raman spectra from a series of 33 solid mixtures containing cocaine, caffeine and glucose (9.8-80.6% by weight cocaine), which were then analysed using chemometric ... -
Quantitative analysis of weakly bound insulin oligomers in solution using polarized multidimensional fluorescence spectroscopy
(Elsevier, 2020-09-08)Being able to measure the size and distribution of oligomers in solution is a critical issue in the manufacture and stability of insulin and other protein formulations. Measuring oligomers reliably can however be complicated, ... -
Quantitative polymorph contaminant analysis in tablets using Raman and near infra-red spectroscopies
(2013)The detection and quantification of alternate polymorphs of active pharmaceutical ingredients (APIs), particularly at low concentrations is a key issue for the manufacture and analysis of solid-state formulations. Each ...