Browsing by Subject "induction"
Now showing items 1-20 of 22
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Antioxidant-mediated inhibition of the heat shock response leads to apoptosis
(Wiley-Blackwell, 1999-02-19) -
Biological activities of lipopolysaccharides are determined by the shape of their lipid a portion
(Wiley-Blackwell, 2000-04-01)Lipopolysaccharide (LPS) represents a major virulence factor of Gram-negative bacteria ('endotoxin') that can cause septic shock in mammals including man. The lipid anchor of LPS to the outer membrane, lipid A, has a ... -
Biological characterization ofcampylobacter fetuslipopolysaccharides
(Oxford University Press (OUP), 1996-08-01)Lipopolysaccharides (LPS) of three strains of Campylobacter fetus (subspp. fetus and venerealis, and serotypes A and B), a bacterium of veterinary importance but also a cause of various infections in humans, were assessed ... -
Cytokine-induced β-cell apoptosis is no-dependent, mitochondria-mediated and inhibited by bcl-xl
(Wiley-Blackwell, 2008-04-01)Pro-inflammatory cytokines are implicated as the main mediators of beta-cell death during type 1 diabetes but the exact mechanisms remain unknown. This study examined the effects of interleukin-1 beta (IL-1 beta), ... -
Determinable and non-determinable parameters of galvanic distortion in magnetotellurics
(Oxford University Press (OUP), 2005-12-01)Galvanic distortion has long been recognized as an obstacle in the interpretation of magnetotelluric (MT) data. One fundamental problem for distortion removal is that the equations that describe the effects of galvanic ... -
Donor bone marrow–derived dendritic cells prolong corneal allograft survival and promote an intragraft immunoregulatory milieu
(Elsevier BV, 2013-11-01)Investigations into cell therapies for application in organ transplantation have grown. Here, we describe the ex vivo generation of donor bone marrow-derived dendritic cells (BMDCs) and glucocorticoid-treated BMDCs with ... -
Effect of helicobacter pylori lipopolysaccharide (lps) and lps derivatives on the production of tissue factor and plasminogen activator inhibitor type 2 by human blood mononuclear cells
(Oxford University Press (OUP), 1996-12-01)Different Helicobacter pylori lipopolysaccharides (LPSs) and LPS-derivatives were studied for their ability to induce the production of procoagulant activity (PCA) and plasminogen activator inhibitor type 2 (PAI-2) by human ... -
Engineering exosomes for cancer therapy
(MDPI AG, 2017-05-24)There remains an urgent need for novel therapeutic strategies to treat metastatic cancer, which results in over 8 million deaths annually worldwide. Following secretion, exosomes are naturally taken up by cells, and capable ... -
Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos
(UPV/EHU Press, 2010-01-01)The insulin-like growth factor (IGF) family is essential for normal embryonic growth and development and it is highly conserved through vertebrate evolution. However, the roles that the individual members of the IGF family ... -
Involvement of capsaicin-sensitive afferent nerves and cholecystokinin 2/gastrin receptors in gastroprotection and adaptation of gastric mucosa to helicobacter pylori-lipopolysaccharide
(American Society for Pharmacology & Experimental Therapeutics (ASPET), 2004-04-02)Lipopolysaccharide (LPS) is one of the virulence factors in the Helicobacter pylori (Hp)-infected stomach, but it remains unknown whether single and prolonged pretreatment with HpLPS can affect the course of gastric damage ... -
Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - a step closer to physiologically relevant in vitro organogenesis
(Springer Nature, 2016-08-01)Modular tissue engineering is based on the cells' innate ability to create bottom-up supramolecular assemblies with efficiency and efficacy still unmatched by man-made devices. Although the regenerative potential of such ... -
Macrophages behavior on different nipam-based thermoresponsive substrates
(Wiley-Blackwell, 2013-09-25) -
Mesenchymal stem cell inhibition of t-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin e2 via the ep4 receptor
(Wiley-Blackwell, 2011-08-30)Mesenchymal stem cells (MSCs) inhibit T-cell activation and proliferation but their effects on individual T-cell-effector pathways and on memory versus naive T cells remain unclear. MSC influence on the differentiation of ... -
Mesenchymal stem cell therapy promotes corneal allograft survival in rats by local and systemic immunomodulation
(Wiley-Blackwell, 2014-08-06)Mesenchymal stemcells (MSCs) are being investigated extensively due to their ability to dampen immune responses. Here, we tested the ability of MSCs from three distinct sources to prolong rat corneal allograft survival. A ... -
N-glycosylation of mouse trail-r and human trail-r1 enhances trail-induced death
(Springer Nature, 2017-02-10)APO2L/TRAIL (TNF-related apoptosis-inducing ligand) induces death of tumor cells through two agonist receptors, TRAIL-R1 and TRAIL-R2. We demonstrate here that N-linked glycosylation (N-glyc) plays also an important ... -
Nitrous oxide/oxygen mixture and the prevention of pain during injection of propofol
(Ovid Technologies (Wolters Kluwer Health), 2003-02-01)Background and objective: The incidence of pain associated with the injection of propofol still remains a problem. This study sought to examine the analgesic effects of inhaled nitrous oxide in oxygen on the prevention of ... -
Nonviral methods for inducing pluripotency to cells
(Hindawi Limited, 2013-01-01)The concept of inducing pluripotency to adult somatic cells by introducing reprogramming factors to them is one that has recently emerged, gained widespread acclaim and garnered much attention among the scientific community. ... -
Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome
(Wiley-Blackwell, 2009-02-01)Objective. Tumor necrosis factor receptor (TNFR) -associated periodic syndrome (TRAPS) is an autosomal-dominant autoinflammatory condition caused by mutations in the TNFRSFIA gene. Unlike other autoinflammatory diseases ... -
Regulating immunogenicity and tolerogenicity of bone marrow-derived dendritic cells through modulation of cell surface glycosylation by dexamethasone treatment
(Frontiers Media SA, 2017-10-30)Dendritic cellular therapies and dendritic cell vaccines show promise for the treatment of autoimmune diseases, the prolongation of graft survival in transplantation, and in educating the immune system to fight cancers. ... -
Role of lentivirus-mediated overexpression of programmed death-ligand 1 on corneal allograft survival
(Wiley-Blackwell, 2012-02-02)To investigate the role of lentivirus-mediated overexpression of programmed death-ligand 1 (PD-L1) on rat corneal allograft survival. A fully allogeneic rat cornea transplant model was used for in vivo studies. Lentiviral ...