Browsing Research Institutes and Centres by Author "Sallent, Ignacio"
Now showing items 1-3 of 3
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Biophysics rules the cell culture but has yet to reach the clinic: Why is that?
Guillaumin, Salomé; Sallent, Ignacio; Zeugolis, Dimitrios I. (Lippincott, Williams & Wilkins, 2017-07)Musculoskeletal injuries are the leading cause of physical disability worldwide, with associated annual direct and indirect healthcare expenditure in excess of $874 billion in the United States alone.1 Current treatments ... -
Production and characterization of chemically cross-linked collagen scaffolds
Sallent, Ignacio; Capella-Monsonís, Héctor; Zeugolis, Dimitrios I. (Humana Press, 2019-03-07)Chemical cross-linking of collagen-based devices is used as a means of increasing the mechanical stability and control the degradation rate upon implantation. Herein, we describe techniques to produce cross-linked with ... -
The synergistic effect of low oxygen tension and macromolecular crowding in the development of extracellular matrix-rich tendon equivalents
Tsiapalis, Dimitrios; De Pieri, Andrea; Spanoudes, Kyriakos; Sallent, Ignacio; Kearns, Stephen; Kelly, Jack L.; Raghunath, Michael; Zeugolis, Dimitrios I. (IOP Publishing, 2020-02-26)Cellular therapies play an important role in tendon tissue engineering, with tenocytes being the most prominent and potent cell population available. However, for the development of a rich extracellular matrix tenocyte-assembled ...