Browsing Research Institutes and Centres by Author "Khan, Yasar"

Now showing items 1-15 of 15

    • Abstract A27: A linked data approach to discover HPV oncoprotiens and RB1 induced mutation associations for the retinoblastoma research 

      Jha, Alokkumar; Khan, Yasar; Rebholz-Schumann, Dietrich; Sahay, Ratnesh (American Association for Cancer Research, 2017-01)
      Background: LOSS or GAIN in tumor suppressor gene RB1 play a significant role as in case of loss low penetrance where only 39% of eye at risk develops in retinoblastoma. This research covers the multiple mutation types and ...

    • Deep convolution neural network model to predict relapse in breast cancer 

      Jha, Alokkumar; Verma, Ghanshyam; Khan, Yasar; Mehmood, Qaiser; Rebholz-Schuhmann, Dietrich; Sahay, Ratnesh (IEEE, 2018-12-17)
      A mishap in anti-cancer drug distribution is critical in breast cancer patients due to poor prediction model to identify the treatment regime in ER+ve and ER-ve (Estrogen Receptor (ER)) patients. The traditional method for ...

    • Demonstrating a linked data platform for finite element biosimulations of cochlear mechanics 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Hasapis, Panagiotis; Sahay, Ratnesh (CEUR-WS.org, 2015-10-11)
      Biosimulations employ Finite Element Method (FEM) to simulate complex biological systems in order to understand different aspects of human organs. The applications of FEM biosimulations range from human ear cochlear mechanics, ...

    • Demonstrating a linked data visualiser for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Raza, Saleem; Hasapis, Panagiotis; Sahay, Ratnesh (IEEE, 2016-02-04)
      Healthcare experts have recently turned towards the use of Biosimulation models to understand the multiple or different causative factors that cause impairment in human organs. The applications of biosimulations have been ...

    • Detecting inner-ear anatomical and clinical datasets in the linked open data (LOD) cloud 

      Mehdi, Muntazir; Iqbal, Aftab; Khan, Yasar; Decker, Stefan; Sahay, Ratnesh (CEUR-WS.org, 2015-10-15)
      Linked Open Data (LOD) Cloud is a mesh of open datasets coming from different domains. Among these datasets, a notable amount of datasets belong to the life sciences domain linked together forming an interlinked “Life ...

    • An evaluation of SPARQL federation engines over multiple endpoints 

      Saleem, Muhammad; Khan, Yasar; Hasnain, Ali; Ermilov, Ivan; Ngonga Ngomo, Axel-Cyrille (NUI Galway, 2018-04-23)
      Due to decentralized and linked architecture underlying Linking Data, running complex queries often require collecting data from multiple RDF datasets. The optimization of the runtime of such queries, called federated ...

    • Extending inner-ear anatomical concepts in the Foundational Model of Anatomy (FMA) ontology 

      Khan, Yasar; Mehdi, Muntazir; Jha, Alokkumar; Raza, Saleem; Freitas, Andre; Jones, Marggie; Sahay, Ratnesh (IEEE, 2015-11-02)
      The inner ear is physically inaccessible in living humans, which leads to unique difficulties in studying its normal function and pathology as in other human organs. Recently, biosimulation model has gained a significant ...

    • Linked data cased multi-omics integration and visualization for cancer decision networks 

      Jha, Alokkumar; Khan, Yasar; Mehmood, Qaiser; Rebholz-Schuhmann, Dietrich; Sahay, Ratnesh (Springer Verlag, 2018-12-30)
      Visualization of Gene Expression (GE) is a challenging task since the number of genes and their associations are difficult to predict in various set of biological studies. GE could be used to understand tissue-gene-protein ...

    • A linked data platform for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Decker, Stefan; Sahay, Ratnesh (ACM, 2015-09-16)
      Biosimulation models have been recently introduced to understand the exact causative factors that give rise to impairment in human organs. Finite Element Method (FEM) provides a mathematical framework to simulate dynamic ...

    • A linked data visualiser for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Raza, Saleem; Hasapis, Panagiotis; Sahay, Ratnesh (IEEE, 2016-02-04)
      Biosimulation models are used to understand the multiple or different causative factors that cause impairment in human organs. Finite Element Method (FEM) provide a mathematical framework to simulate dynamic biological ...

    • A linked data visualiser for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Jares, Joao; Freitas, Andre; Jha, Alok Kumar; Sakellarios, Antonis; Sahay, Ratnesh (World Scientific Publishing, 2016)
      Biosimulation models are used to understand the multiple or different causative factors that cause impairment in human organs. Finite Element Method (FEM) provide a mathematical framework to simulate dynamic biological ...

    • Linked functional annotation for differentially expressed gene (DEG) demonstrated using Illumina Body Map 2.0 

      Jha, Alokkumar; Khan, Yasar; Iqbal, Aftab; Zappa, Achille; Mehdi, Muntazir; Sahay, Ratnesh; Rebholz-Schuhmann, Dietrich (CEUR-WS.org, 2015-12-09)
      Semantic Web technologies are core for the integration of disparate data resources. It can be used to exploit data from next generation sequencing (NGS) for therapeutic decisions regarding cancer. In this manuscript, ...

    • One size does not fit all: querying web polystores 

      Khan, Yasar; Zimmermann, Antoine; Jha, Alokkumar; Gadepally, Vijay; d'Aquin, Mathieu; Sahay, Ratnesh (IEEE, 2019-01-17)
      Data retrieval systems are facing a paradigm shift due to the proliferation of specialized data storage engines (SQL, NoSQL, Column Stores, MapReduce, Data Stream, and Graph) supported by varied data models (CSV, JSON, ...

    • SAFE: SPARQL federation over RDF data cubes with access control 

      Khan, Yasar; Saleem, Muhammad; Mehdi, Muntazir; Hogan, Aidan; Mehmood, Qaiser; Rebholz-Schuhmann, Dietrich; Sahay, Ratnesh (BioMed Central, 2017-02-01)
      Several query federation engines have been proposed for accessing public Linked Open Data sources. However, in many domains, resources are sensitive and access to these resources is tightly controlled by stakeholders; ...

    • Towards precision medicine: discovering novel gynecological cancer biomarkers and pathways using linked data 

      Jha, Alokkumar; Khan, Yasar; Mehdi, Muntazir; Karim, Md Rezaul; Mehmood, Qaiser; Zappa, Achille; Rebholz-Schuhmann, Dietrich; Sahay, Ratnesh (BioMed Central, 2017-09-19)
      Next Generation Sequencing (NGS) is playing a key role in therapeutic decision making for the cancer prognosis and treatment. The NGS technologies are producing a massive amount of sequencing datasets. Often, these datasets ...