Abstract A27: A linked data approach to discover HPV oncoprotiens and RB1 induced mutation associations for the retinoblastoma research
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2017-01Author
Jha, Alokkumar
Khan, Yasar
Rebholz-Schumann, Dietrich
Sahay, Ratnesh
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Jha, Alokkumar, Khan, Yasar, Rebholz-Schumann, Dietrich, & Sahay, Ratnesh. (2017). Abstract A27: A linked data approach to discover HPV oncoprotiens and RB1 induced mutation associations for the retinoblastoma research. Cancer Research, 77(2 Supplement), A27-A27. doi: 10.1158/1538-7445.epso16-a27
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Abstract
Background: LOSS or GAIN in tumor suppressor gene RB1 play a significant role as in case of loss low penetrance where only 39% of eye at risk develops in retinoblastoma. This research covers the multiple mutation types and its effects and identification of major type of mutation involved in retinoblastoma because of HPV and RB1.