Browsing University of Galway Theses (PhD Theses) by Subject "MRSA"
Now showing items 1-6 of 6
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Ctrl-atl-delete: Re-thinking the mechanisms of biofilm formation by staphylococci
(2015-04-07)Biofilm formation by staphylococci on implanted medical devices represents a major virulence mechanism and a serious threat to hospital patients. Staphylococcus aureus strains including, methicillin-resistant S. aureus ... -
Exploiting homogeneous oxacillin resistance in methicillin resistant staphylococcus aureus to Identify novel anti-virulence therapeutic targets
(2017-06-08)The number of antibiotic-resistant bacterial infections have continued to increase in recent years and have drawn global concern to the potential future of living in a post-antibiotic era. These infections are of major ... -
From the membrane to central metabolism: New insights into the diverse mechanisms controlling β-lactam resistance in MRSA
(NUI Galway, 2022-01-07)Staphylococcus aureus is an important human pathogen, with the ability to colonise and cause disease, ranging in severity from superficial skin infections to life threatening invasive disease. The emergence of healthcare ... -
Pathogen genomics of methicillin resistant staphylococcus aureus and leishmania
(2017-02-15)Infectious diseases caused by the single-celled eukaryotic parasite Leishmania and the methicillin-resistant Staphylococcus aureus (MRSA) bacterium are major public health problems in many countries. In this thesis, I use ... -
A study into two pillars of staphylococcal pathogenicity: biofilm and antibiotic resistance
(NUI Galway, 2018-10-22)Biofilm formation on inserted medical devices by the opportunistic pathogen, Staphylococcus epidermidis, continues to be constant threat in clinical health-care settings. Once established, biofilms are almost impossible ... -
The X Factor(s): New antibiotic resistance mechanisms in community-associated methicillin resistant Staphylococcus aureus
(2017-03-31)Methicillin-resistant Staphylococcus aureus (MRSA) strains typically express low-level heterogeneous (HeR) resistance from which high-level homogeneously resistant (HoR) mutants can be isolated following oxacillin exposure. ...