Browsing University of Galway Theses (PhD Theses) by Author "Dennedy, Michael Conall"

Now showing items 1-3 of 3

    • An investigation of the immunometabolic interactions of obesity 

      Dennedy, Michael Conall (2013-09-04)
      Human monocytes are classified as classical, intermediate and non-classical according to their surface expression of CD14 and CD16. They also represent precursors to atherogenic foam cells and macrophages in metabolically ...

    • The role of the liver X receptor in mitotane therapy in adrenocortical carcinoma 

      Warde, Kate (NUI Galway, 2020-08-12)
      Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with limited treatment options. The Liver X Receptor α (LXRα) is highly expressed in the adrenal cortex, and functions to regulate cholesterol and lipid ...

    • Subtotal ablation and hyperthermia in the adrenal cortex 

      Donlon, Padraig (NUI Galway, 2021-08)
      Primary aldosteronism (PA) accounts for 5–12% of all hypertension and confers a higher risk for cardiovascular and cerebrovascular complications compared to age and blood pressure (BP) matched essential hypertension. PA ...