Browsing NUI Galway Theses (PhD Theses) by Subject "Carbohydrates"
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The anomerisation of glycosyl thiols and synthesis of multivalent GlcNAc and GalNAc glycoclusters
(2015-04-29)There are several published procedures available for the synthesis of b-thiopyranoses such as gluco- or galacto-pyranoses. Given the ease with which one can access such b -thiopyranoses, the development of a reproducible ... -
Development and Application of a Computational Method for Determining the Specificity of Glycan-binding Proteins
(2013-09-25)Changes in cell-surface glycan patterns are markers for the presence of many different disease and cancer types, offering a relatively untapped niche for glycan-targeting reagents and therapeutics in diagnosis and treatment. ... -
Synthesis of S-glycolipids and peptidomimetics
(2011-08-19)Chapters one and two of this thesis describe the synthesis of two novel glycosphingolipid derivatives. Glycosphingolipids are amphiphilic molecules consisting of a carbohydrate head group glycosidically linked to a sphingoid ...