Browsing University of Galway Theses (PhD Theses) by Subject "Angiogenesis"
Now showing items 1-5 of 5
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Biological characterization of a human mesenchymal stromal cell product
(2016-07-21)The translation of stem cell research into a therapeutic setting presents with it many scientific, logistic, financial and regulatory challenges for academic scientists. This thesis identifies some key areas that one must ... -
Development of a microgel-based cell delivery platform for critical limb ischemia
(2017-05-05)Peripheral Arterial Diseases (PAD) is a chronic and debilitating disease caused due to narrowing and hardening of arteries, that results in progressive deterioration of blood flow to the limbs. PAD commonly occurs in the ... -
Elastin-like polypeptide mediated proangiogenic and anti-inflammatory gene therapy for critical limb ischemia
(2014-12-17)Critical limb ischemia is a major clinical problem. Despite rigorous treatment regimes, there has been modest success in reducing the rate of amputations in these patients. Reduced level of blood flow and enhanced inflammation ... -
A multi-modal collagen nucleic acid delivery system for the modulation of inflammation and promotion of angiogenesis
(2014-12-15)Tissue engineered organs and implants hold promise for the replacement of damaged and diseased organs. However, the foreign body response (FBR) is a major obstacle that compromises the function of tissue engineered constructs, ... -
Vascular plasticity and target for therapy in Duchenne muscular dystrophy
(NUI Galway, 2023-06-13)Angiogenesis is the growth of new blood vessels from pre-existing vessels, necessary for the growth and maintenance of homeostasis. Duchenne muscular dystrophy (DMD) is a debilitating disease of the musculoskeletal ...