Browsing University of Galway Theses (PhD Theses) by Subject "chemotherapic drugs"
Now showing items 1-1 of 1
-
Dissecting the evolution of resistance to microtubule hyper-stabilization
(NUI Galway, 2024-01-31)When microtubules are hyper-stabilized, they do not provide the proper tension at the kinetochore of the metaphase chromosomes. Low tension leads to the activation of the spindle assembly checkpoint which stops cells ...