Browsing University of Galway Theses (PhD Theses) by Author "van Vuuren, Chelly"
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A refined model of nucleolar formation derived from the analysis of UBF variants and the hierarchical silencing of human nucleolar organizer regions
van Vuuren, Chelly (NUI Galway, 2017-03-23)The nucleolus, the largest sub-nuclear structure, forms around arrays of ribosomal RNA genes, termed nucleolar organizer regions (NORs). As the site of ribosome biogenesis, nucleolar function is intrinsically linked to ...