Browsing University of Galway Theses (PhD Theses) by Author "Schlosser, Gerhard"
Now showing items 1-4 of 4
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Dissecting the pan-placodal gene regulatory network reveals novel interactions driving sense organ development in vertebrates
Riddiford, Nick (2016-02-17)The genes encoding the transcription factor Six1, and its co-factor Eya1 together mark the embryonic territory - the pan-placodal ectoderm (PPE) - that gives rise to most cranial sense organs in vertebrates. Mutation of ... -
Investigating the roles of MARCKS and MARCKS-like 1 proteins in Xenopus laevis spinal cord development and regeneration
El Amri, Mohamed (NUI Galway, 2024-02-12)The identification and characterisation of key molecules that can promote or suppress regeneration has been an elusive, long-sought objective for researchers in spinal cord injury. The myristoylated alanine-rich C-kinase ... -
Regulation of Six1 and Eya1 during the formation of the preplacodal ectoderm in xenopus - towards a gene regulatory network of the developing neural plate border
Maharana, Santosh (2017-01-06)Cranial placodes are ectodermal thickenings in vertebrate embryos that give rise to many sense organs and ganglia. All placodes arise from a common precursor, the pre-placodal ectoderm (PPE). The latter develops during ... -
The role of Eya1 in otic neurogenesis in Xenopus laevis
Almasoudi, Suad (NUI Galway, 2021-07-26)Cranial placodes are specialized areas of thickening of the early embryonic ectoderm at the head and give rise to sensory organs and ganglia. In vertebrates, the inner ear is derived from one of these placodes, the otic ...