Browsing University of Galway Theses (PhD Theses) by Author "Lowndes, Noel Francis"
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Analysis of Saccharomyces cerevisiae Mec1 and Rad9 functions in the DNA Damage Response
De Castro Abreu, Carla Manuela (2012-10-01)The maintenance of genome integrity is critical for cell proliferation and survival of all organisms. Central to the DNA Damage Response are signal-transduction pathways, termed DNA damage checkpoints, conserved from ... -
Characterisation of novel ATM-interacting factors involved in double-strand break repair
Pessina, Fabio (2012-10-22)Ataxia-telangiectasia (A-T) is a rare human disease characterized by cerebellar degeneration, immune system defects and cancer predisposition. The disease has been the subject of intense scientific scrutiny, particularly ...