Browsing University of Galway Theses (PhD Theses) by Author "Halpin-McCormick, Anna"
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Identifying novel strategies to re-engage the apoptotic pathway for the treatment of cancer
Halpin-McCormick, Anna (2014-09-30)In chapter two we demonstrate that in non-transformed cells multiple signalling pathways control TRAIL resistance and they act in a redundant manner. This is contrary, however, to the resistance mechanisms found in tumour ...