Browsing University of Galway Theses (PhD Theses) by Author "Gupta, Sanjeev"
Now showing items 1-4 of 4
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Management of chemotherapy-induced neutropenia in cancer patients
Abbasi, Benazir (NUI Galway, 2023-03-06)Chemotherapy is widely used as a successful treatment option for cancer patients, showing a higher success rate in hematological cancers than solid tumours. Chemotherapy-induced neutropenia (CIN), defined as “a reduction ... -
PERK-dependent molecular mechanisms in breast cancer progression and treatment
Sultana, Afrin (NUI Galway, 2023-06-16)Stressful conditions of the tumour microenvironment, which overwhelm the folding capacity of the endoplasmic reticulum (EnR), activate an evolutionarily conserved signalling pathway known as the unfolded protein response ... -
Regulation of cell fate by microRNAs during unfolded protein response and its role in cancer
Arabkari, Vahid (NUI Galway, 2018-12-20)The endoplasmic reticulum (EnR) stress is a common phenomenon in various cancers such as breast, colorectal, skin and hepatocellular carcinoma. Several pathophysiological events (e.g., radiation, aneuploidy, oncogenic ... -
Role of MicroRNAs and unfolded protein response in breast cancer
Hossain, Muhammad Mosaraf (2017-11-24)Stressful conditions of the tumour microenvironment which overwhelm the folding capacity of the endoplasmic reticulum (EnR) activate an evolutionary conserved signalling pathway known as the unfolded protein response (UPR). ...