Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 654-673 of 2245
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Enhancing knowledge graph completion models and selected biological applications
(NUI Galway, 2020-06-18)Knowledge completion is the task of extending knowledge graphs to enhance the quality of systems relying on them. In recent years, various knowledge completion techniques were developed to model knowledge graphs using ... -
Enhancing spectrum sensing performance for the cognitive radio based internet of things
(NUI Galway, 2021-12-26)In cognitive radio based internet of things (CR-IoT) networks spectrum sensing and decision making processes to determine whether the primary user (PU) signal is present or absent in the network are very important and ... -
Enhancing the bioavailability of active pharmaceutical ingredients through cocrystallization and coamorphization
(NUI Galway, 2019-12-19)During drug research and development, improving the solubility of poorly water soluble drugs without chemically modifying the drug molecule is one of the biggest challenges for the pharmaceutical industry. Most medicines ... -
Enhancing the efficacy and therapeutic potential of human mesenchymal stromal cells (hMSCs) in clinically relevant sepsis models
(NUI Galway, 2022-08-30)Rationale: Sepsis is a systemic inflammatory process produced by the reaction of the immune system against a pathogen. This inflammatory process produces tissue damage leading into vital organ malfunction and, if not ... -
Enhancing the immunomodulatory capacity and therapeutic potential of mesenchymal stromal cell-derived small extracellular vesicles through cytokine licensing
(NUI Galway, 2023-09-12)The immunomodulatory capacity of mesenchymal stromal cells (MSCs) is well established, and is being explored as a cellular therapy for the treatment of various inflammatory-based conditions. In recent years, the role of ... -
Enhancing the immunomodulatory efficacy of allogeneic mesenchymal stromal cells through pro-inflammatory cytokine licensing
(NUI Galway, 2024-04-17)The therapeutic efficacy and immunomodulatory potential of mesenchymal stromal cells (MSCs) is well established. MSCs have been employed as cellular therapies to treat various inflammatory-based conditions. MSC potency can ... -
Enhancing the situational awareness of the active distribution network
(NUI Galway, 2022-06-21)Power distribution system operation has become increasingly complex with the large-scale integration of Distributed Energy Resources (DERs). This has led to a paradigm shift in the operation and planning of the power ... -
Enhancing trust in detecting security threats using machine learning approaches and its application in the Internet of Things
(NUI Galway, 2022-12-13)Identifying network attacks is a very crucial task for network security. The increasing amount of network devices is creating a massive amount of data and opening new security vulnerabilities that malicious users can ... -
Enhancing willingness to whistleblow internally: The role of leaders and work culture
(NUI Galway, 2021-03-30)Whistleblowing research shows that leaders play an essential role in steering ethical behaviour and work culture. This thesis investigates the factors that enhance employee willingness to internal speak up and how leadership ... -
Enterprise education in post-primary schools: An exploration of the antecedent and contextual factors that impact on successful provision
(NUI Galway, 2020-04-30)Enterprise education is universally lauded as a means to enabling an enterprising capacity in young citizens who benefit the local and national economy while also being one of the eight European Union key competences. ... -
Entity summarisation for entity-centric publish/subscribe systems
(NUI Galway, 2021-12-21)The Internet of Things (IoT) has contributed to physical devices generating entity-centric data (e.g. smart buildings). To bridge the gap between the devices’ data and the users’ interests, Publish/Subscribe systems (Pub/Sub) ... -
Entrepreneurial networking and the development of marketing capabilities in SMEs. A study of Irish entrepreneurs
(2016-09-16)It is widely accepted across the marketing, entrepreneurship and strategic management literatures that relationships and networks are instrumental for the growth and performance of SMEs. In particular, in the entrepreneurial ... -
Entrepreneurial self-efficacy (ESE): a business model approach
(2016-04-07)Researchers of entrepreneurship lack a general, yet distinct, conceptual framework that both describes how entrepreneurial action occurs and predicts who does it. Some scholars have noted that the emerging concept of ... -
Entry pattern matrices
(NUI Galway, 2019-03-29)An entry pattern matrix (EPM for short) is a rectangular matrix in which each entry is an indeterminate. The same indeterminate may appear in multiple positions, but different indeterminates are independent. For a field ... -
Environmental and genetic risk factors in Autism Spectrum Disorder: a stereological study
(NUI Galway, 2020-07-15)Autism spectrum disorders (ASD), include a group of heterogeneous neurodevelopmental disorders (NDDs) characterized by impaired social interaction, and communication with restricted patterns of behaviour. The aetiology ... -
Environmental aqueous geochemistry of arsenic in groundwater: occurrence, speciation and biogeochemical processes
(NUI Galway, 2020-04-27)The presence of arsenic and other trace elements within groundwater has become a global concern due to the health risks from drinking water associated with elevated concentrations in the last three decades. Whilst ample ... -
Environmental assessment of freshwater aquaculture in Ireland
(NUI Galway, 2020-12-11)Aquaculture is the fastest growing food production activity in the world and has been for the last several decades. With over 60% of wild fish stocks at or below their maximum sustainable yield, it is expected that to ... -
Enzymes in the World of Computational Chemistry - Computational Studies on Structures, Dynamics, Mechanisms, and Specificity of Five Biologically Important Enzymes
(2012-10-30)The thesis demonstrates computational chemical methodology applied to some biologically important enzymes. Five enzymes have been studied, i.e. sortase A (SrtA), 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase ... -
Epigenetic regulation of germline stem cell fate by Centromere Protein C
(NUI Galway, 2021-01-21)Germline stem cells (GSCs) divide asymmetrically to produce one new daughter stem cell and one daughter cell that will subsequently undergo meiosis and differentiate to generate the mature gamete. The ‘silent sister ... -
Epigenetic regulation of NOD-like receptor activity and expression
(NUI Galway, 2018-11-19)NOD-like receptors (NLRs) are a family of intracellular pathogen recognition receptors involved in the innate immune response. NOD1 and NOD2 are the best characterised members of this family, and so are the focus of this ...