Browsing College of Science by Subject "CANCER"
Now showing items 1-3 of 3
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A Cu(II) complex targeting the translocator protein: in vitro and in vivo antitumor potential and mechanistic insights
(Royal Society of Chemistry, 2016-12-01)A new Cu-based anticancer metallodrug which targets the translocator protein is reported. [CuBr2(TZ6)] elicits a remarkable in vitro cytotoxicity in sensitive and multidrug resistant cell lines and induces a 98% reduction ... -
Cytotoxicity and ROS production of novel Pt(IV) oxaliplatin derivatives with indole propionic acid
(Elsevier, 2019-04-19)The coordination of biologically active moieties to the axial positions of Pt(IV) derivatives of Pt(II) anticancer drugs allows the co-delivery and simultaneous activation of two pro-drugs for combination therapy. Pt(IV) ... -
Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation
(2013)We present depth-resolved spatial-domain low-coherence quantitative phase microscopy, a simple approach that utilizes coherence gating to construct a depth-resolved structural feature vector quantifying sub-resolution axial ...