Browsing College of Science by Author "College of Science, National University of Ireland, Galway"
Now showing items 1-5 of 5
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Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function
Flynn, Mairéad; Whitton, Laura; Donohoe, Gary; Morrison, Ciaran G.; Morris, Derek W. (Oxford University Press (OUP), 2019-12-23)Mutations in genes that encode centrosomal/ciliary proteins cause severe cognitive deficits, while common single-nucleotide polymorphisms in these genes are associated with schizophrenia (SZ) and cognition in genome-wide ... -
A Bpp-based dinuclear ruthenium photocatalyst for visible light-driven oxidation reactions
Hennessey, Seán; Farràs, Pau; Benet-Buchholz, Jordi; Llobet, Antoni (Royal Society of Chemistry, 2019-11-05)A diruthenium dyad molecule consisting of a 2,2-(1H-pyrazole-3,5-diyl)dipyridine (Hbpp) bridging ligand with the formula out-/in-[(bpy)2Ru(bpp)Ru(L)(tpy)]n+ (bpy = 2,2′-bipyridine, tpy = 2,2′:6′,2′′-terpyridine, L = Cl, ... -
Building blocks from monosaccharides for synthesis of scaffolds, including macrocycles. Application of allylic azide rearrangement, azide-alkyne cycloaddition and ring closing metathesis
Fox, Karen A.; Chadda, Rekha; Cardona, Francisco; Barron, Stephen; McArdle, Patrick; Murphy, Paul V. (Elsevier, 2020-09-18)Synthesis of compounds with characteristics of natural products are required to increase the diversity and biological relevance of compounds for screening. These include new frameworks/scaffolds, with multiple stereogenic ... -
Effect of individual plasma components on the performance of a glucose enzyme electrode based on redox polymer mediation of a flavin adenine dinucleotide-dependent glucose dehydrogenase
Bennett, Richard; Blochouse, Estelle; Leech, Dónal (Elsevier, 2019-02-11)The performance of glucose enzyme electrodes, consisting of crosslinked flavin adenine dinucleotide glucose dehydrogenase (FADGDH), an osmium redox polymer and multi-walled carbon nanotubes on graphite electrodes, was ... -
Proton resonance frequency shift thermometry: A review of modern clinical practices
Blackwell, James; Kraśny, Marcin J.; O'Brien, Aoife; Ashkan, Keyoumars; Galligan, Josette; Destrade, Michel; Colgan, Niall (Wiley, 2020-11-20)Magnetic resonance imaging (MRI) has become a popular modality in guiding minimally invasive thermal therapies, due to its advanced, nonionizing, imaging capabilities and its ability to record changes in temperature. A ...