Browsing College of Science by Title
Now showing items 578-597 of 976
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Multiwavelength Observations of Markarian 421 in March 2001: an Unprecedented View on the X-ray/TeV Correlated Variability
(2007)(Abridged) We present a detailed analysis of week-long simultaneous observations of the blazar Mrk421 at 2-60 keV X-rays (RXTE) and TeV gamma-rays (Whipple and HEGRA) in 2001. The unprecedented quality of this dataset ... -
Multiwavelength observations of Mrk 501 in 2008
(EDP Sciences, 2015-12-17)Context. Blazars are variable sources on various timescales over a broad energy range spanning from radio to very high energy (>100 GeV, hereafter VHE). Mrk 501 is one of the brightest blazars at TeV energies and has been ... -
Multiwavelength Observations of the Previously Unidentified Blazar RX J0648.7+1516
(2011)We report on the VERITAS discovery of very-high-energy (VHE) gamma- ray emission above 200 GeV from the high-frequency-peaked BL Lac object RXJ0648.7+1516 (GBJ0648+1516), associated with 1FGLJ0648.8+1516. The photon spectrum ... -
Multiwavelength Observations of the VHE Blazar 1ES 2344+514
(2011)Multiwavelength observations of the high-frequency-peaked blazar 1ES2344+514 were performed from 2007 October to 2008 January. The campaign represents the first contemporaneous data on the object at very high energy (VHE, ... -
Multiwavelength study of quiescent states of MRK 421 with unprecedented hard x-ray coverage provided by NuSTAR in 2013
(IOP Publishing, 2016)We present coordinated multiwavelength observations of the bright, nearby BL Lacertae object Mrk 421 taken in 2013 January-March, involving GASP-WEBT, Swift, NuSTAR, Fermi-LAT, MAGIC, VERITAS, and other collaborations and ... -
N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines
(Elsevier, 2018-12-04)1,5-Dideoxy-1,5-imino-l-fucitol (1-deoxyfuconojirimycin, DFJ) is an iminosugar that inhibits fucosidases. Herein, N-alkyl DFJs have been synthesised and tested against the ¿-fucosidases of T. maritima (bacterial origin) ... -
N=2 and N=4 subalgebras of super vertex operator algebras
(IOP Publishing, 2018-01-10)We develop criteria to decide if an N=2 or N=4 super conformal algebra is a subalgebra of a super vertex operator algebra in general, and of a super lattice theory in particular. We give some specific examples. -
Nano-sensitive optical coherence tomography
(Royal Society of Chemistry, 2014)Depth resolved label-free detection of structural changes with nanoscale sensitivity is an outstanding problem in the biological and physical sciences and has significant applications in both the fundamental research and ... -
Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography
(Royal Society of Chemistry, 2020-05-25)Approximately 90% of cancers originate in epithelial tissues leading to epithelial thickening, but the ultrastructural changes and underlying architecture are less well known. Depth resolved label free visualization of ... -
Nanosensitive optical coherence tomography for the study of changes in static and dynamic structures
(IOP Science, 2014-03-06)We briefly discuss the principle of image formation in Fourier domain optical coherence tomography (OCT). The theory of a new approach to improve dramatically the sensitivity of conventional OCT is described. The approach ... -
Nanosensitive optical coherence tomography to assess wound healing within the cornea
(Optical Society of America, 2020-05-01)Optical coherence tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though ... -
Nash Equilibria in certain two-choice multi-player games played on the ladder graph
(World Scientific Publishing, 2021-01-16)In this paper, we compute analytically the number of Nash Equilibria (NE) for a two-choice game played on a (circular) ladder graph with 2n players. We consider a set of games with generic payoff parameters, with the only ... -
The natural bile acid surfactant sodium taurocholate (NaTC) as a coformer in coamorphous systems: Enhanced physical stability and dissolution behavior of coamorphous drug-NaTc systems
(Elsevier, 2018-10-28)The amorphization of 18 different drugs on milling with one mole equivalent sodium taurocholate (NaTC) was investigated. In all cases the X-ray powder pattern showed an amorphous halo after milling at room temperature or ... -
The nature of fracture permeability in the basement greywacke at Kawerau Geothermal Field, New Zealand
(Stanford University, 2012-01-30)The Mesozoic basement at Kawerau Geothermal Field comprises well indurated, inter-bedded sandstones and argillites with a complex structural history. These rocks have very low matrix porosity but nonetheless host both ... -
Nerve growth factor (NGF)-mediated regulation of p75(NTR) expression contributes to chemotherapeutic resistance in triple negative breast cancer cells
(Elsevier, 2016)Triple negative breast cancer [TNBC] cells are reported to secrete the neurotrophin nerve growth factor [NGF] and express its receptors, p75 neurotrophin receptor [p75(NTR)] and TrkA, leading to NGF-activated pro-survival ... -
Nerve Growth Factor in Cancer Cell Death and Survival
(MDPI, 2011-02)One of the major challenges for cancer therapeutics is the resistance of many tumor cells to induction of cell death due to pro-survival signaling in the cancer cells. Here we review the growing literature which shows that ... -
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
(Nature Publishing Group, 2014-05-01)Nerve growth factor (NGF) is well characterised as an important pro-survival factor in neuronal cells that can inhibit apoptotic cell death upstream of mitochondrial outer membrane permeabilisation. Here we addressed the ... -
Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
(Wiley, 2008-06-27)Neuronal cell death plays a role in many chronic neurodegenerative diseases with the loss of particular subsets of neurons. The loss of the neurons occurs during a period of many years, which can make the mode(s) of cell ... -
Neurotrophins and B-cell malignancies
(Springer Verlag, 2015-09-23)Neurotrophins and their receptors act as important proliferative and pro-survival factors in a variety of cell types. Neurotrophins are produced by multiple cell types in both pro and mature forms, and can act in an autocrine ... -
A new era for homolytic aromatic substitution: replacing Bu3SnH with efficient light-induced chain reactions
(Royal Society of Chemistry, 2016-04-01)Herein is a pertinent review of recent photochemical homolytic aromatic substitution (HAS) literature. Issues with using the reductant Bu3SnH in an oxidative process where the net loss of a hydrogen atom occurs is discussed. ...