Browsing College of Science by Title
Now showing items 558-577 of 938
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N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines
(Elsevier, 2018-12-04)1,5-Dideoxy-1,5-imino-l-fucitol (1-deoxyfuconojirimycin, DFJ) is an iminosugar that inhibits fucosidases. Herein, N-alkyl DFJs have been synthesised and tested against the ¿-fucosidases of T. maritima (bacterial origin) ... -
N=2 and N=4 subalgebras of super vertex operator algebras
(IOP Publishing, 2018-01-10)We develop criteria to decide if an N=2 or N=4 super conformal algebra is a subalgebra of a super vertex operator algebra in general, and of a super lattice theory in particular. We give some specific examples. -
Nano-sensitive optical coherence tomography
(Royal Society of Chemistry, 2014)Depth resolved label-free detection of structural changes with nanoscale sensitivity is an outstanding problem in the biological and physical sciences and has significant applications in both the fundamental research and ... -
Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography
(Royal Society of Chemistry, 2020-05-25)Approximately 90% of cancers originate in epithelial tissues leading to epithelial thickening, but the ultrastructural changes and underlying architecture are less well known. Depth resolved label free visualization of ... -
Nanosensitive optical coherence tomography for the study of changes in static and dynamic structures
(IOP Science, 2014-03-06)We briefly discuss the principle of image formation in Fourier domain optical coherence tomography (OCT). The theory of a new approach to improve dramatically the sensitivity of conventional OCT is described. The approach ... -
Nanosensitive optical coherence tomography to assess wound healing within the cornea
(Optical Society of America, 2020-05-01)Optical coherence tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though ... -
Nash Equilibria in certain two-choice multi-player games played on the ladder graph
(World Scientific Publishing, 2021-01-16)In this paper, we compute analytically the number of Nash Equilibria (NE) for a two-choice game played on a (circular) ladder graph with 2n players. We consider a set of games with generic payoff parameters, with the only ... -
The natural bile acid surfactant sodium taurocholate (NaTC) as a coformer in coamorphous systems: Enhanced physical stability and dissolution behavior of coamorphous drug-NaTc systems
(Elsevier, 2018-10-28)The amorphization of 18 different drugs on milling with one mole equivalent sodium taurocholate (NaTC) was investigated. In all cases the X-ray powder pattern showed an amorphous halo after milling at room temperature or ... -
The nature of fracture permeability in the basement greywacke at Kawerau Geothermal Field, New Zealand
(Stanford University, 2012-01-30)The Mesozoic basement at Kawerau Geothermal Field comprises well indurated, inter-bedded sandstones and argillites with a complex structural history. These rocks have very low matrix porosity but nonetheless host both ... -
Nerve growth factor (NGF)-mediated regulation of p75(NTR) expression contributes to chemotherapeutic resistance in triple negative breast cancer cells
(Elsevier, 2016)Triple negative breast cancer [TNBC] cells are reported to secrete the neurotrophin nerve growth factor [NGF] and express its receptors, p75 neurotrophin receptor [p75(NTR)] and TrkA, leading to NGF-activated pro-survival ... -
Nerve Growth Factor in Cancer Cell Death and Survival
(MDPI, 2011-02)One of the major challenges for cancer therapeutics is the resistance of many tumor cells to induction of cell death due to pro-survival signaling in the cancer cells. Here we review the growing literature which shows that ... -
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
(Nature Publishing Group, 2014-05-01)Nerve growth factor (NGF) is well characterised as an important pro-survival factor in neuronal cells that can inhibit apoptotic cell death upstream of mitochondrial outer membrane permeabilisation. Here we addressed the ... -
Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
(Wiley, 2008-06-27)Neuronal cell death plays a role in many chronic neurodegenerative diseases with the loss of particular subsets of neurons. The loss of the neurons occurs during a period of many years, which can make the mode(s) of cell ... -
Neurotrophins and B-cell malignancies
(Springer Verlag, 2015-09-23)Neurotrophins and their receptors act as important proliferative and pro-survival factors in a variety of cell types. Neurotrophins are produced by multiple cell types in both pro and mature forms, and can act in an autocrine ... -
A new era for homolytic aromatic substitution: replacing Bu3SnH with efficient light-induced chain reactions
(Royal Society of Chemistry, 2016-04-01)Herein is a pertinent review of recent photochemical homolytic aromatic substitution (HAS) literature. Issues with using the reductant Bu3SnH in an oxidative process where the net loss of a hydrogen atom occurs is discussed. ... -
New experimental insights into acetylene oxidation through novel ignition delay times, laminar burning velocities and chemical kinetic modelling
(Elsevier, 2018-08-03)The oxidation of acetylene is central to the oxidation of virtually all hydrocarbon fuels. It is also important for commercial industry, due to its wide range of applications such as flame photometry, atomic absorption, ... -
New Zealand geothermal power plants as critical facilities: an active fault avoidance study in the Wairakei Geothermal Field, New Zealand
(International Geothermal Association, 2015-04-19)Active faults in rifts commonly provide high crustal permeability and control geothermal fluid pathways. However, active faults can also pose surface deformation hazards to geothermal power plants and associated infrastructure. ... -
NHDC and PHDC: Non-propagating and propagating heat diffusion classifiers
(12th International Conference on Neural Information Processing, 2005)Abstract - By imitating the way that heat flows in a medium with a geometric structure, we propose two novel classification algorithms, Non-propagating Heat Diffusion Classifier (NHDC) and Propagating Heat Diffusion ... -
Non-invasive evaluation of skin tension lines with elastic waves
(Wiley, 2017-11-20)Background: Since their discovery by Karl Langer in the 19th Century, Skin Tension Lines (STLs) have been used by surgeons to decide the location and orientation of an incision. Although these lines are patient-specific, ... -
Non-principal surface waves in deformed incompressible materials
(Elsevier, 2005)The Stroh formalism is applied to the analysis of infinitesimal surface wave propagation in a statically, finitely and homogeneously deformed isotropic half-space. The free surface is assumed to coincide with one of the ...