Browsing College of Science by Author "http://dx.doi.org/10.13039/100010269"
Now showing items 1-5 of 5
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Functional responses and adaptation of mesophilic microbial communities to psychrophilic anaerobic digestion
Gunnigle, Eoin; Nielsen, Jeppe L.; Fuszard, Matthew; Botting, Catherine H.; Sheahan, Jerome; O'Flaherty, Vincent; Abram, Florence (Oxford University Press, 2015-10-27)Psychrophilic (<20°C) anaerobic digestion (AD) represents an attractive alternative to mesophilic wastewater treatment. In order to investigate the AD microbiome response to temperature change, with particular emphasis on ... -
An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis
Morris, Derek W. (Oxford University Press (OUP), 2014-01-28)Identifying rare, highly penetrant risk mutations may be an important step in dissecting the molecular etiology of schizophrenia. We conducted a gene-based analysis of large (>100 kb), rare copy-number variants (CNVs) in ... -
Linking microbial community structure and function during the acidified anaerobic digestion of grass
Joyce, Aoife; Ijaz, Umer Z.; Nzeteu, Corine; Vaughan, Aoife; Shirran, Sally L.; Botting, Catherine H.; Quince, Christopher; O’Flaherty, Vincent; Abram, Florence (Frontiers Media, 2018-03-21)Harvesting valuable bioproducts from various renewable feedstocks is necessary for the critical development of a sustainable bioeconomy. Anaerobic digestion is a well-established technology for the conversion of wastewater ... -
Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, Denise; Connolly, Siobhan; Riley, Brien P.; Kendler, Kenneth S.; McCarthy, Shane E.; McCombie, William R.; Richards, Alex; Owen, Michael J.; O'Donovan, Michael C.; Walters, James; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Donohoe, Gary; Gill, Michael; Corvin, Aiden; Morris, Derek W. (Wiley, 2019-02-23)Genome‐wide association studies (GWASs) are highly effective at identifying common risk variants for schizophrenia. Rare risk variants are also important contributors to schizophrenia etiology but, with the exception of ... -
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster
Mills, Wilbur Kyle; Lee, Yuh Chwen G.; Kochendoerfer, Antje M.; Dunleavy, Elaine M.; Karpen, Gary H. (eLife Sciences Publications, 2019-11-05)Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that ...