Browsing School of Chemistry (Scholarly Articles) by Author "Gordon, Fiona"
Now showing items 1-3 of 3
-
Advanced spectroscopy and APBS modeling for determination of the role of His190 and Trp103 in mouse thymidylate synthase interaction with selected dUMP analogues
Prokopowicz, Małgorzata; Jarmuła, Adam; Casamayou-Boucau, Yannick; Gordon, Fiona; Ryder, Alan; Sobich, Justyna; Maj, Piotr; Cieśla, Joanna; Zieliński, Zbigniew; Fita, Piotr; Rode, Wojciech (MDPI, 2021-03-06)A homo-dimeric enzyme, thymidylate synthase (TS), has been a long-standing molecular target in chemotherapy. To further elucidate properties and interactions with ligands of wild-type mouse thymidylate synthase (mTS) and ... -
Evaluating the interaction of human serum albumin (HSA) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes in different aqueous environments using anisotropy resolved multi-dimensional emission spectroscopy (ARMES)
Gordon, Fiona; Casamayou-Boucau, Yannick; Ryder, Alan G. (Elsevier, 2022-01-07)Studying the interaction between plasma proteins and liposomes is critical, particularly for their use as drug delivery systems. Here, the efficacy of anisotropy resolved multidimensional emission spectroscopy (ARMES) for ... -
Modelling Förster resonance energy transfer (FRET) using anisotropy resolved multi-dimensional emission spectroscopy (ARMES)
Gordon, Fiona; Elcoroaristizabal, Saioa; Ryder, Alan G. (Elsevier, 2020-11-16)Background Förster Resonance Energy Transfer (FRET) is widely used to study the structure and dynamics of biomolecular systems and also causes the non-linear fluorescence response observed in multi-fluorophore proteins. ...