Browsing School of Chemistry by Author "Leech, Dónal"
Now showing items 1-13 of 13
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Amperometric flow injection analysis of glucose and galactose based on engineered pyranose 2-oxidases and osmium polymers for biosensor applications
Kurbanoglu, Sevinc; Zafar, Muhammed Nadeem; Tasca, Federico; Aslam, Iqra; Spadiut, Oliver; Leech, Dónal; Haltrich, Dietmar; Gorton, Lo (Wiley, 2018-04-25)In the present study, wild type and three mutants of pyranose 2-oxidase (PyOx-WT, PyOx-MT1, PyOx-MT2, PyOx-MT3), which showed improved properties for D-galactose oxidation, were investigated for their oxidising ability ... -
Bioelectrochemical Haber-Bosch process: An ammonia-producing H-2/N-2 fuel cell
Milton, Ross D.; Cai, Rong; Abdellaoui, Sofiene; Leech, Dónal; De Lacey, Antonio L.; Pita, Marcos; Minteer, Shelley D. (Wiley, 2017-02-03)Nitrogenases are the only enzymes known to reduce molecular nitrogen (N-2) to ammonia (NH3). By using methyl viologen (N, N'-dimethyl-4,4'-bipyridinium) to shuttle electrons to nitrogenase, N-2 reduction to NH3 can be ... -
Comparison of performance of an earthen plate and nafion as membrane separators in dual chamber microbial fuel cells
Jana, Partha Sarathi; Ghangrekar, Makarand Madhao; Leech, Dónal (Universitatea Tehnica "Gheorghe Asachi" Iasi. Editura Politehnium, Romania, 2018-02)The performance of microbial fuel cells (MFC) employing an earthen plate as a membrane separator is compared to that using Nafion 117 in an identical up-flow dual-chambered cylindrical cell configuration. The MFC configuration ... -
Cost-effective wireless microcontroller for internet connectivity of open-source chemical devices
Mercer, Conan; Leech, Dónal (American Chemical Society, 2018-06-04)This paper presents a system for remote monitoring of turbidity data that can detect light intensity and temperature using a microcontroller and the Internet of Things. The system comprises a light dependent resistor and ... -
Design of experiments approach to provide enhanced glucose-oxidising enzyme electrode for membrane-less enzymatic fuel cells operating in human physiological fluids
Bennett, Richard; Osadebe, Isioma; Kumar, Rakesh; Ó Conghaile, Peter; Leech, Dónal (Wiley, 2018-03-30)Graphite electrodes are modified with a redox polymer, [Os(4,4-dimethoxy-2,2-bipyridine)(2)(polyvinylimidazole)(10)Cl](+) (E degrees=-0.02V vs Ag/AgCl (3M KCl), crosslinked with a flavin adenine dinucleotide glucose ... -
Effect of individual plasma components on the performance of a glucose enzyme electrode based on redox polymer mediation of a flavin adenine dinucleotide-dependent glucose dehydrogenase
Bennett, Richard; Blochouse, Estelle; Leech, Dónal (Elsevier, 2019-02-11)The performance of glucose enzyme electrodes, consisting of crosslinked flavin adenine dinucleotide glucose dehydrogenase (FADGDH), an osmium redox polymer and multi-walled carbon nanotubes on graphite electrodes, was ... -
Electrochemical glucose biosensor based on an osmium redox polymer and glucose oxidase grafted to carbon nanotubes: A design-of-experiments optimisation of current density and stability
Jayakumar, Kavita; Bennett, Richard; Leech, Dónal (Elsevier, 2021-01-25)Enzymatic glucose electrodes based on mediated electron transfer have potential for application as semi-implantable or implantable sensors. Enzyme electrodes consisting of adsorbed osmium-based redox polymer crosslinked ... -
Extracellular electron transfer by the gram-positive bacterium enterococcus faecalis
Pankratova, Galina; Leech, Dónal; Gorton, Lo; Hederstedt, Lars (American Chemical Society, 2018-07-10)Extracellular electron transfer (EET) in microbial cells is essential for certain biotechnological applications and contributes to the biogeochemical cycling of elements and syntrophic microbial metabolism in complex natural ... -
Glucose biosensor based on open-source wireless microfluidic potentiostat
Mercer, Conan; Bennett, Richard; Ó Conghaile, Peter; Rusling, James F.; Leech, Dónal (Elsevier, 2019-02-17)Wireless potentiostats capable of cyclic voltammetry and amperometry that connect to the Internet are emerging as key attributes of future point-of-care devices. This work presents an "integrated microfluidic electrochemical ... -
The in vivo potential-regulated protective protein of nitrogenase in azotobacter vinelandii supports aerobic bioelectrochemical dinitrogen reduction in vitro
Milton, Ross D.; Cai, Rong; Sahin, Selmihan; Abdellaoui, Sofiene; Alkotaini, Bassam; Leech, Dónal; Minteer, Shelley D. (American Chemical Society, 2017-06-08)Nitrogenase, the only enzyme known to be able to reduce dinitrogen (N-2) to ammonia (NH3), is irreversibly damaged upon exposure to molecular oxygen (O-2). Several microbes, however, are able to grow aerobically and ... -
The influence of surface composition of carbon nanotubes on the photobioelectrochemical activity of thylakoid bioanodes mediated by osmium-complex modified redox polymer
Pankratov, Dmitry; Zhao, Jianming; Nur, Mohammed Ahmed; Shen, Fei; Leech, Dónal; Chi, Qijin; Pankratova, Galina; Gorton, Lo (Elsevier, 2019-04-17)A combination of photosynthetic biocatalysts with high surface area conductive materials mediated by an osmium-complex modified redox polymer (OsRP) holds promising features for the development of sustainable "green" systems ... -
Multiplexed electrochemical cancer diagnostics with automated microfluidics
Mercer, Conan; Jones, Abby; Rusling, James F.; Leech, Dónal (Wiley, 2018-11-27)Microfluidic platforms can lead to miniaturisation, increased throughput and reduced reagent consumption, particularly when the processes are automated. Here, a programmable microcontroller is used for automation of a ... -
Powering fuel cells through biocatalysis
Leech, Dónal; Pellissier, Marie; Barrière, Frédéric (Academic Press, 2007-11-27)[No abstract available]