Browsing School of Chemistry by Author "|~|6201984|~|"
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Anisotropy resolved multidimensional emission spectroscopy (ARMES): A new tool for protein analysis
Groza, Radu Constantin; Ryder, Alan G.; Li, Boyan (Elsevier, 2015-07-30)Structural analysis of proteins using the emission of intrinsic fluorophores is complicated by spectral overlap. Anisotropy resolved multidimensional emission spectroscopy (ARMES) overcame the overlap problem by the use ... -
CO2-responsive polyacrylamide copolymer vesicles with acid-sensitive morpholine moieties and large hydrophobic RAFT end-group
Chalmers, Benjamin A.; Magee, Christopher; Cheung, David L.; Zetterlund, Per B.; Aldabbagh, Fawaz (Elsevier, 2017-10-07)Sequential Reversible Addition Fragmentation Chain Transfer (RAFT) polymerizations using 2,2′-azobis[2-(2-imidazolin-2-yl)propane]dihydrochloride (VA-044) and 2-(dodecylthiocarbonothioylthio)-2-methylpropionic acid ... -
Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition
Sweeney, Martin; Coyle, Robert; Kavanagh, Paul; Berezin, Andrey A.; Lo Re, Daniele; Zissimou, Georgia A.; Koutentis, Panayiotis A.; Carty, Michael P.; Aldabbagh, Fawaz (Elsevier, 2016-05-30)The thioredoxin (Trx)-thioredoxin reductase (TrxR) system plays a key role in maintaining the cellular redox balance with Trx being over-expressed in a number of cancers. Inhibition of TrxR is an important strategy for ...