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Electrochemiluminescent array to detect oxidative damage in ds-dna using [os(bpy)2(phen-benz-cooh)]2+/nafion/graphene films
(American Chemical Society (ACS), 2016-03-25)
Reactive oxygen species (ROS) oxidize guanosines in DNA to form 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG), a biomarker for oxidative stress. Herein we describe a novel 64-microwell electrochemiluminescent (ECL) array ...
Electrochemiluminescence arrays for studies of metabolite-related toxicity
(Wiley-Blackwell, 2016-06-01)
This article reviews recent progress from our laboratory in electrochemiluminescence (ECL) arrays designed for screening toxicity-related chemistry of chemical and drug candidates. Cytochrome P450s and metabolic bioconjugation ...
Electrochemiluminescence at bare and dna-coated graphite electrodes in 3d-printed fluidic devices
(American Chemical Society (ACS), 2016-02-26)
Clear plastic fluidic devices with ports for incorporating electrodes to enable electrochemiluminescence (ECL) measurements were prepared using a low-cost, desktop three-dimensional (3D) printer based on stereolithography. ...
Multiplex immunosensor arrays for electrochemical detection of cancer biomarker proteins
(Wiley-Blackwell, 2016-06-07)
Measuring panels of protein biomarkers offer a new personalized approach to early cancer detection, disease monitoring and patients' response to therapy. Multiplex electrochemical methods are uniquely positioned to provide ...